Patents by Inventor Aleksandr Valerevich GRACHEV

Aleksandr Valerevich GRACHEV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Trispecific antibodies against IL-17A, IL-17F and other pro-inflammatory molecule
    Patent number: 11453717
    Abstract: The present invention relates to the field of biotechnology and provides monoclonal tri-specific binding molecules that specifically bind to human IL-17A, human IL-17F, and a human pro-inflammatory molecule (in particular, TNF?) with high affinity. The invention also relates to DNA constructs encoding said binding molecules, related expression vectors and methods of production, and methods of treatment using said binding molecules.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 27, 2022
    Inventors: Dmitry Valentinovich Morozov, Andrei Borisovich Ulitin, Ekaterina Sergeevna Zubareva, Iakov Iurevich Ustiugov, Aleksandr Vladimirovich Karabelskii, Dmitry Valeryevich Korzhavin, Tatiana Veniaminovna Chernovskaya, Aleksandr Valerevich Grachev, Yury Ivanovich Basovskiy, Ekaterina Aleksandrovna Lomkova, Veronika Sergeevna Usatova, Aleksei Aleksandrovich Aleksandrov, Elena Leonidovna Morozova, Roman Alekseevich Ivanov, Pavel Andreevich Iakovlev
  • TRISPECIFIC ANTIBODIES AGAINST IL-17A, IL-17F AND OTHER PRO-INFLAMMATORY MOLECULE
    Publication number: 20210332120
    Abstract: The present invention relates to the field of biotechnology and provides monoclonal tri-specific binding molecules that specifically bind to human IL-17A, human IL-17F, and a human pro-inflammatory molecule (in particular, TNF?) with high affinity. The invention also relates to DNA constructs encoding said binding molecules, related expression vectors and methods of production, and methods of treatment using said binding molecules.
    Type: Application
    Filed: December 2, 2016
    Publication date: October 28, 2021
    Inventors: Dmitry Valentinovich MOROZOV, Andrei Borisovich ULITIN, Ekaterina Sergeevna ZUBAREVA, Iakov Iurevich USTIUGOV, Aleksandr Vladimirovich KARABELSKII, Dmitry Valeryevich KORZHAVIN, Tatiana Veniaminovna CHERNOVSKAYA, Aleksandr Valerevich GRACHEV, Yury Ivanovich BASOVSKIY, Ekaterina Aleksandrovna LOMKOVA, Veronika Sergeevna USATOVA, Aleksei Aleksandrovich ALEKSANDROV, Elena Leonidovna MOROZOVA, Roman Alekseevich IVANOV, Pavel Andreevich IAKOVLEV