Patents by Inventor Aleksandra Niedzwiecki

Aleksandra Niedzwiecki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911363
    Abstract: A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
    Type: Grant
    Filed: January 6, 2023
    Date of Patent: February 27, 2024
    Inventors: Matthias Rath, Vadim Ivanov, Aleksandra Niedzwiecki
  • Publication number: 20230144808
    Abstract: A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
    Type: Application
    Filed: January 6, 2023
    Publication date: May 11, 2023
    Inventors: Matthias RATH, Vadim IVANOV, Aleksandra NIEDZWIECKI
  • Patent number: 11590103
    Abstract: A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: February 28, 2023
    Inventors: Matthias Rath, Vadim Ivanov, Aleksandra Niedzwiecki
  • Patent number: 11547693
    Abstract: A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: January 10, 2023
    Inventors: Matthias Rath, Vadim Ivanov, Aleksandra Niedzwiecki
  • Publication number: 20210205267
    Abstract: A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
    Type: Application
    Filed: March 25, 2021
    Publication date: July 8, 2021
    Inventors: Matthias RATH, Vadim IVANOV, Aleksandra NIEDZWIECKI
  • Publication number: 20210030715
    Abstract: A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
    Type: Application
    Filed: July 29, 2019
    Publication date: February 4, 2021
    Inventors: Matthias RATH, Vadim IVANOV, Aleksandra NIEDZWIECKI
  • Patent number: 10716767
    Abstract: The nutrient mixture made up of vitamin, carotenoid, micronutrient, essential trace element, and plant extract was much more effective in proactively protecting the corneal cells (human) and retinal pigment endothelial cells (rat) against damaging effects of H2O2 and glycosylated proteins (AGE-BSA) compared to its individual components. A mixture is made up of vitamin A, vitamin C, vitamin E, Lycopene, lutein, marigold flower extract, a saffron extract, pine bark extract, grape seed extract, bilberry extract, lipoic acid, L-Arginine and zinc.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: July 21, 2020
    Inventors: Aleksandra Niedzwiecki, Matthias W Rath, Anna Goc, Waldemar Sumera
  • Publication number: 20190209489
    Abstract: The nutrient mixture made up of vitamin, carotenoid, micronutrient, essential trace element, and plant extract was much more effective in proactively protecting the corneal cells (human) and retinal pigment endothelial cells (rat) against damaging effects of H2O2 and glycosylated proteins (AGE-BSA) compared to its individual components. A mixture is made up of vitamin A, vitamin C, vitamin E, Lycopene, lutein, marigold flower extract, a saffron extract, pine bark extract, grape seed extract, bilberry extract, lipoic acid, L-Arginine and zinc.
    Type: Application
    Filed: January 9, 2018
    Publication date: July 11, 2019
    Inventors: Aleksandra Niedzwiecki, Matthias W. Rath, Anna Goc, Waldemar Sumera
  • Patent number: 10238619
    Abstract: A composition of a fatty acids, essential oils, plant extracts, phenols, and terpenoids and used for treating Lyme disease is disclosed. Compositions as a mix of ingredients was tested in various combinations and concentration against active (spirochetes), as well as persistent/latent forms, (knob-shaped/rounded-forms) and biofilm of the bacteria, i.e., Borrelia burgdorferi and Borrelia garinii. The results document pleiotropic effects of the tested combinations against all tested forms of Borrelia sp. and show their better efficacy than doxycycline—the current antibiotic treatment against Lyme disease.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: March 26, 2019
    Inventors: Matthias W Rath, Aleksandra Niedzwiecki, Anna Goc
  • Publication number: 20170348280
    Abstract: A therapeutic use of ascorbyl palmitate, ascorbic acid and/or derivatives thereof to reverse or counter the adverse effects of channel blockers in the medical management of cardiovascular disease in a subject is presented. Effects of select Na- and Ca-channel blockers on collagen synthesis and deposition were evaluated in cultured human dermal fibroblasts and aortic smooth muscle cells by immunoassay. Ca and Na-channel blockers inhibited the synthesis of collagen type I and collagen type IV, the basic molecules of vascular wall stability. The inhibitory effects of the calcium and sodium channel blockers on collagen synthesis was reversed by introducing ascorbic acid and/or ascorbyl palmitate. It can be concluded that calcium and sodium channel blockers have a direct inhibitory effect on collagen synthesis, favoring the instability of the vascular wall and the progression of cardiovascular disease, an effect that is mitigated by treatment with, ascorbyl palmitate, ascorbic acid and or derivatives thereof.
    Type: Application
    Filed: June 6, 2016
    Publication date: December 7, 2017
    Inventors: MATTHIAS W RATH, Aleksandra Niedzwiecki, Vadim O. Ivanov, Svetlana V. Ivanova
  • Publication number: 20160339057
    Abstract: Lyme disease caused by B. burgdorferi and B. garinii has been traditionally treated with antibiotics. However, to eradicate all three morphological forms of Borrelia species such as spirochetes, rounded bodies and biofilm more effective and safe treatment plan is required. In the instant application, Vitamins and Phytobiologicals have been tested for as a short term and long term treatment in vitro and on biofilm. The combination of tested compounds in form of Mix AO seems to be very beneficial in treating Lyme disease caused by B. burgdorferi and B. garinii.
    Type: Application
    Filed: August 5, 2016
    Publication date: November 24, 2016
    Inventors: MATTHIAS W. RATH, Aleksandra Niedzwiecki, Anna Goc
  • Publication number: 20160106777
    Abstract: A composition for treating Lyme disease caused by Borrelia Species, comprising a vitamin, a small fatty acid signaling molecule, an essential amino acid, a flavonoid, a plant extract and a mineral.
    Type: Application
    Filed: October 19, 2014
    Publication date: April 21, 2016
    Inventors: Matthias W. Rath, Aleksandra Niedzwiecki, Anna Goc
  • Patent number: 9101334
    Abstract: A method and technology to display 3D graphical output for a user using body sensor data, personal medical data in real time is disclosed. A consolidated methodology to bring user meaningful life information based on real-time sensor results, analysis, expert Q&As, “What if” scenarios and future emulation all in one artificial intelligence expert system is described. A unique rendering of 3D image of ones organ, cell or subcellular level display related to one's health condition can be visualized on a graphical user interface of a devices or devices. The change of the display from one level such as from organ to cell or cell to subcellular level or vice versa is enabled is disclosed.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: August 11, 2015
    Inventors: Matthias W Rath, Aleksandra Niedzwiecki, Dirk Fried Karnath
  • Publication number: 20150149217
    Abstract: A method and technology to display 3D graphical output for a user using body sensor data, personal medical data in real time is disclosed. A consolidated methodology to bring user meaningful life information based on real-time sensor results, analysis, expert Q&As, “What if” scenarios and future emulation all in one artificial intelligence expert system is described. A unique rendering of 3D image of ones organ, cell or subcellular level display related to one's health condition can be visualized on a graphical user interface of a devices or devices. The change of the display from one level such as from organ to cell or cell to subcellular level or vice versa is enabled is disclosed.
    Type: Application
    Filed: February 4, 2015
    Publication date: May 28, 2015
    Inventors: MATTHIAS W. RATH, Aleksandra Niedzwiecki, Dirk Fried Karnath
  • Patent number: 9018437
    Abstract: The invention discloses novel model of transgenic mammal, a method of crossbreeding transgenic mammal and the use of the transgenic mammal for assessing prevention and/or treatment methods for cardiovascular and other diseases related to lipoprotein(a). The transgenic mammal expresses human apolipoprotein (a) (apo(a)) and human apolipoprotein B-100 (apo B-100) genes and produces human lipoprotein (a), apo (a) and apo B-100 and produces no vitamin C. This novel dual transgenic mammal is the ideal model for testing pharmaceutical compounds for efficacy and usefulness in the prevention and/or treatment of human diseases.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: April 28, 2015
    Inventors: Matthias W Rath, Aleksandra Niedzwiecki, John Chang-Eun Cha
  • Publication number: 20150074837
    Abstract: The invention discloses novel model of transgenic mammal, a method of crossbreeding transgenic mammal and the use of the transgenic mammal for assessing prevention and/or treatment methods for cardiovascular and other diseases related to lipoprotein(a). The transgenic mammal expresses human apolipoprotein (a) (apo(a)) and human apolipoprotein B-100 (apo B-100) genes and produces human lipoprotein (a), apo (a) and apo B-100 and produces no vitamin C. This novel dual transgenic mammal is the ideal model for testing pharmaceutical compounds for efficacy and usefulness in the prevention and/or treatment of human diseases.
    Type: Application
    Filed: September 12, 2013
    Publication date: March 12, 2015
    Inventors: MATTHIAS W RATH, Aleksandra Niedzwiecki, JOHN CHANG-EUN CHA
  • Publication number: 20150074835
    Abstract: The invention discloses novel model of transgenic mammal, a method of crossbreeding transgenic mammal and the use of the transgenic mammal for assessing prevention and/or treatment methods for cardiovascular and other diseases related to lipoprotein(a). The transgenic mammal expresses human apolipoprotein (a) (apo(a)) and human apolipoprotein B-100 (apo B-100) genes and produces human lipoprotein (a), apo (a) and apo B-100 and produces no vitamin C. This novel dual transgenic mammal is the ideal model for testing pharmaceutical compounds for efficacy and usefulness in the prevention and/or treatment of human diseases.
    Type: Application
    Filed: October 5, 2014
    Publication date: March 12, 2015
    Inventors: MATTHIAS W. RATH, Aleksandra Niedzwiecki, JOHN CHANG-EUN CHA
  • Patent number: 8968004
    Abstract: Several methods, processes and system for modular tool as an integrated multimedia tool system to explore and study the virtual human body is disclosed. Content and context modules allow for scientific gaming using modular multimedia objects, social media and different configurations. The disclosure allows an individual to travel through the virtual human body in a self guided and interactive tour. It specifically enables the user to learn the structure and function of different organs, different types of cells, intercellular space as well as different cellular organelles etc. Further, the system may be used by the local authority as an electronic study tool for seamless integrated mode of delivering the educational tool suited to the local curriculum. This may also serve as a tool for patients, doctors, focus groups and student to explore and learn about the pathological and physiological conditions in a human body.
    Type: Grant
    Filed: August 13, 2011
    Date of Patent: March 3, 2015
    Inventors: Matthias W. Rath, Aleksandra Niedzwiecki
  • Publication number: 20130040273
    Abstract: Several methods, processes and system for modular tool as an integrated multimedia tool system to explore and study the virtual human body is disclosed. Content and context modules allow for scientific gaming using modular multimedia objects, social media and different configurations. The disclosure allows an individual to travel through the virtual human body in a self guided and interactive tour. It specifically enables the user to learn the structure and function of different organs, different types of cells, intercellular space as well as different cellular organelles etc. Further, the system may be used by the local authority as an electronic study tool for seamless integrated mode of delivering the educational tool suited to the local curriculum. This may also serve as a tool for patients, doctors, focus groups and student to explore and learn about the pathological and physiological conditions in a human body.
    Type: Application
    Filed: August 13, 2011
    Publication date: February 14, 2013
    Inventors: Matthias W. Rath, Aleksandra Niedzwiecki
  • Publication number: 20130040274
    Abstract: A novel integrated system and method for visualizing human physiology, disease and treatment options are described in the instant application. The graphical rendering of the human body is in depth and the user can explore the internal workings of the organs and cells by simply performing a pealing like act using a cursor and the layer as a flap opens up to show the details. A user can click on a specific topic and watch a video, narration or text relevant to the topic of choice. The integrated system provides storage of curated data, social media access and interaction, database storage and analytics to calculate user behavior. This technology may used as an application on any mobile and hardware device.
    Type: Application
    Filed: June 18, 2012
    Publication date: February 14, 2013
    Inventors: MATTHIAS W. RATH, Aleksandra Niedzwiecki, Markus Haecki