Abstract: A 3D printing system can include an extruding system, curing system and feedback system. The extruding system can include a feed pipe coupled to a printing material source and a nozzle that extrudes a printed material. The feedback system can include a processor and sensors and can detect the temperature and location of the curing system during the printing process. The curing system cures the printed material after extrusion and includes curing sources coupled to a mounting arrangement, which can be a curved surface. The curing sources can each be directed toward a focal region located proximate the nozzle outlet and can combine to emit a combined curing energy to the focal region. The curing sources can be LEDs and the curing energy can be UV light. The curing system can rotate about an axis during printing and curing to facilitate rapid movement and printing of complex 3D objects.

Abstract: A method for detection of an organic analyte in a liquid sample, the method including: providing an assay substrate comprising a first component and a second component; the first component including a sensor molecule labeled with a quantum dot, the quantum dot immobilized to an assay substrate surface with a first linker, the sensor molecule having a specific binding site for an organic analyte, the sensor molecule labeled with the quantum dot in a position that has no effect on the organic analyte binding the specific binding site; the second component including a chemical analogue of the organic analyte, the chemical analogue labeled with a fluorescent dye, the chemical analogue linked to the quantum dot with a second linker having a length exceeding Förster radius, and the chemical analogue reversibly binding the specific binding site of the sensor molecule of the first component; applying the liquid sample to the assay substrate; illuminating the assay substrate to excite fluorescence of the quantum dot;

Abstract: An assay substrate including a first component comprising a sensor molecule labeled with a quantum dot, the quantum dot immobilized to an assay substrate surface with a first linker being a bi-polar linker comprising a first binding group for specific binding of the quantum dot and a second binding group for specific binding of the assay substrate surface, the sensor molecule having a specific binding site for an organic analyte, the sensor molecule labeled with the quantum dot in a position that has no effect on the organic analyte binding the specific binding site; and a second component comprising a chemical analogue of the organic analyte, the chemical analogue labeled with a fluorescent dye, the chemical analogue linked to the quantum dot with a second linker having a length exceeding Foster radius, and the chemical analogue reversibly binding the specific binding site of the sensor molecule of the first component.

Abstract: An assay substrate including a first component comprising a sensor molecule labeled with a quantum dot, the quantum dot immobilized to an assay substrate surface with a first linker being a bi-polar linker comprising a first binding group for specific binding of the quantum dot and a second binding group for specific binding of the assay substrate surface, the sensor molecule having a specific binding site for an organic analyte, the sensor molecule labeled with the quantum dot in a position that has no effect on the organic analyte binding the specific binding site; and a second component comprising a chemical analogue of the organic analyte, the chemical analogue labeled with a fluorescent dye, the chemical analogue linked to the quantum dot with a second linker having a length exceeding Foster radius, and the chemical analogue reversibly binding the specific binding site of the sensor molecule of the first component.

Abstract: A method and a device for detection and quantification of various organic analytes in a liquid sample and an assay substrate for providing analyte measurements. The method is implemented by using specific interaction of organic analytes with selective binding sites immobilized on a multi-layer assay substrate with further detection of such interaction with a device based on inducing and recording the fluorescence of the substrate for bio-chemical, genetic and environmental analyses.

Abstract: The present invention relates to a method and device for measuring acetone concentrations in breath. Measuring acetone concentrations is based on changes the spectral properties of the fluorophore caused by the chemical interaction of a specific fluorophore with the exhaled air containing acetone which.

Abstract: A method and a device for detection and quantification of various organic analytes in a liquid sample and an assay substrate for providing analyte measurements. The method is implemented by using specific interaction of organic analytes with selective binding sites immobilized on a multi-layer assay substrate with further detection of such interaction with a device based on inducing and recording the fluorescence of the substrate for bio-chemical, genetic and environmental analyses.

Abstract: The present invention is related with the optical instrument such as interferometer for testing the optical systems and samples whereas the optical instrument comprises the laser (1) for generating the laser beam which passes the beam expander (2), beam-splitter (23) dividing the laser beam to a working light beam and reference light beam, focusing objectives (3, 7), flat glass plate (4) with one side coated by thin metal highly reflecting coating with the pattern including a pinhole, computer (12), CCD camera (13), tested part or optical system (6). In addition the optical instrument comprises at least two flat mirrors (24, 25), observation objective and at least one stop (20) placed between the beam-splitter (23), flat mirrors (24, 25) and/or focusing objective (7).