Abstract: A system is provided for developing a predictive immunity profile on the basis of the quantitative analysis of one or more samples from an individual. The system comprises: a device configured to perform quantitative analysis of the interaction between one or more target species and one or more probes in solution on a fluid sample to provided quantitative analysis data; a data store storing: personal data relating to at least one individual; at least one model of target/probe interaction; processing circuitry configured to access the data store and identify and retrieve data relevant to the sample; receive quantitative analysis data of the sample from the device; perform analysis to fit the model to the received quantitative analysis data; extrapolate, through the model, to create a predictive immunity profile for the individual, and update the data store with the quantitative analysis data.

Abstract: A computer implemented method of predicting liquid-liquid phase separation LLPS) behaviour of a biomolecule, the method comprising: inputting information identifying the biomolecule and its environmental composition and/or chemical modification of the biomolecule to an algorithm configured to predict, whether the biomolecule will exhibit LLPS under specified environmental conditions and/or chemical modification of the biomolecule, wherein: the algorithm is an algorithm generated by machine learning trained on data featurised according to features relating to biomolecules in the training data and features relating to the environmental conditions and/or chemical modification of the biomolecules in the training data, and the algorithm outputs a prediction of whether the biomolecule will exhibit LLPS under the specified environmental conditions and/or chemical modification of the biomolecule.

Abstract: A system is provided for improving the quantitative analysis of a sample. The system comprises a device; a data store and processing circuitry configured to operate the system. The device is configured to perform quantitative analysis of bio-macromolecular interactions in solution on a fluid sample to provided quantitative analysis data. The data store stores: personal data relating to a plurality of individuals; and data relating to bio-macromolecular interactions.

Abstract: The present invention relates to the identification of proteins involving measurement and characterisation of multidimensional aspects of said proteins.