Patents by Inventor Alem Ghiorghis

Alem Ghiorghis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Progesterone analogs to reverse multidrug resistance
    Patent number: 6143737
    Abstract: The present invention is directed to compounds of formula I ##STR1## wherein the substituents are as defined in the specification. Also disclosed are compositions and method of use of the compounds.
    Type: Grant
    Filed: June 21, 1996
    Date of Patent: November 7, 2000
    Assignee: Georgetown University
    Inventors: Robert Clarke, Abdel H. Talebian, Alem Ghiorghis, Fabio Leonessa, Charles Hammer
  • Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof
    Patent number: 5091523
    Abstract: The invention relates to certain derivatives of mitomycins A and C and the use thereof to treat bacterial infections and to supress the growth of cancer cells. The invention also relates to processes for the preparation of the mitomycin derivatives of the invention.
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: February 25, 1992
    Assignee: Georgetown University
    Inventors: Abdolhossen Talebian, Dianna Green, Charles Hammer, Philip Schein, Alem Ghiorghis, Robert R. Clarke