Patents by Inventor Alemseged Truneh

Alemseged Truneh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor necrosis factor related receptor, TR6
    Patent number: 6313269
    Abstract: TR6 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR6 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (e.g. inflammatory bowel disease, psoriasis), transplant rejection, graft vs. host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, Bone diseases, cancer, atheroschlerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: November 6, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Keith C. Deen, Peter R. Young, Lisa A. Marshall, Amy K. Roshak, Kong B. Tan, Alemseged Truneh
  • PIGR-1, a member of immunoglobulin gene superfamily
    Patent number: 6232441
    Abstract: PIGR-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGR-1 polypeptides and polynucleotides in the design of protocols for the treatment of rheumatoid arthritis (RA), multiple sclerosis (MS), psoriasis, systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD), among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: May 15, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Shujian Wu, Raymond W Sweet, Alemseged Truneh, Mark Robert Hurle
  • PIGRL-1, a member of immunoglobulin gene superfamily
    Patent number: 6114515
    Abstract: PIGRL-1 polypeptide and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGRL-1 polypeptide and polynucleotides in the design of protocols for the treatment of Hyper-IgM Immunodeficiency (HIM), X-linked Severe Combined Immunodeficiency (XSCID), and IgA deficiency (IgA-D), among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: October 30, 1997
    Date of Patent: September 5, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Shujian Wu, Raymond W. Sweet, Alemseged Truneh
  • Human LIG-1 homolog (HLIG-1)
    Patent number: 6046030
    Abstract: HLIG-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HLIG-1 polypeptides and polynucleotides in the design of protocols for the treatment of neurological disorders such as Alzheimer's disease, multiple sclerosis and abnormal neural development; endocrine disorders such as diabetes; and heart disease, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: April 4, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Shujian Wu, Raymond W Sweet, Alemseged Truneh
  • PIGR-1, a member of immunoglobulin gene superfamily
    Patent number: 6020161
    Abstract: PIGR-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGR-1 polypeptides and polynucleotides in the design of protocols for the treatment of rheumatoid arthritis (RA), multiple sclerosis (MS), psoriasis, systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD), among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: February 1, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Shujian Wu, Raymond W Sweet, Alemseged Truneh, Mark Robert Hurle
  • DNA encoding tumor necrosis related receptor, TR4
    Patent number: 5885800
    Abstract: TR4 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR4 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (eg inflammatory bowel disease, psoriasis), transplant rejection, graft vs. host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, Bone diseases, cancer (eg lymphoproliferative disorders), atheroschlerosis, and Alzheimers disease among others, and diagnostic assays for such conditions.
    Type: Grant
    Filed: February 4, 1997
    Date of Patent: March 23, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: John Emery, KB Tan, Alemseged Truneh, Peter R. Young