Patents by Inventor Alessandra Casano

Alessandra Casano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIPLE MECHANISMS FOR MODULATION OF JAK/STAT ACTIVITY
    Publication number: 20100209929
    Abstract: An embodiment of the present invention is a method for subjecting a hematopoetic cell to a JAK/STAT inhibitor, determining the activity of gain-of-function mutations of a Jak family kinase, determining the expression levels and activity of JAK/STAT regulatory proteins, correlating the expression levels and the activity of JAK/STAT regulatory proteins with the activity of gain-of-function mutations of a Jak family kinase and with a response to the JAK/STAT inhibitor, and then classifying the cells. A further embodiment of the invention includes determining the clinical outcome based on the cell classification, determining a method of treatment, determining dosing and scheduling of at least one of the JAK/STAT inhibitors or other compounds.
    Type: Application
    Filed: January 14, 2010
    Publication date: August 19, 2010
    Applicant: Nodality, Inc., A Delaware Corporation
    Inventors: Wendy J. Fantl, Alessandra Casano, Todd Covey