Patents by Inventor Alessandra Cervino

Alessandra Cervino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240075117
    Abstract: The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
    Type: Application
    Filed: June 26, 2023
    Publication date: March 7, 2024
    Inventors: Laurent CHENE, Alessandra Cervino, Francesco Strozzi, Celia Mendez, Christophe Bonny
  • Patent number: 11898210
    Abstract: The present invention relates to an in vitro method for identifying subjects hosting high amounts of Fim H expressing proteobacteria in their gut, said method comprising the step of detecting the expression of the fimH gene in a stool sample of said subjects.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: February 13, 2024
    Assignee: ENTEROME
    Inventors: Alessandra Cervino, Christophe Bonny, Jonathan Plassais
  • Patent number: 11712465
    Abstract: The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: August 1, 2023
    Assignee: ENTEROME S.A.
    Inventors: Laurent Chene, Alessandra Cervino, Francesco Strozzi, Celia Mendez, Christophe Bonny
  • Publication number: 20200277655
    Abstract: The present invention relates to an in vitro method for identifying subjects hosting high amounts of Fim H expressing proteobacteria in their gut, said method comprising the step of detecting the expression of the fimH gene in a stool sample of said subjects.
    Type: Application
    Filed: October 16, 2018
    Publication date: September 3, 2020
    Inventors: Alessandra CERVINO, Christophe BONNY, Jonathan PLASSAIS
  • Publication number: 20200256877
    Abstract: The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
    Type: Application
    Filed: October 9, 2018
    Publication date: August 13, 2020
    Inventors: Laurent CHENE, Francesco STROZZI, Christophe BONNY, Alessandra CERVINO, Celia MENDEZ
  • Publication number: 20200025774
    Abstract: The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
    Type: Application
    Filed: October 9, 2017
    Publication date: January 23, 2020
    Applicant: ENTEROME S.A.
    Inventors: Laurent CHENE, Alessandra CERVINO, Francesco STROZZI, Celia MENDEZ, Christophe BONNY
  • Publication number: 20150240304
    Abstract: This invention refers to the field of human medicine and specifically to the diagnosis/prognosis of the responsiveness to a cytokine targeting drug (Cy TD) or an anti-inflammatory biological drug treatment of a subject suffering from an inflammatory disease.
    Type: Application
    Filed: January 25, 2012
    Publication date: August 27, 2015
    Inventors: Alessandra Cervino, Oana Popa-Nita, Jonathan Plassais
  • Publication number: 20130095099
    Abstract: The invention concerns methods for the in vitro diagnosis/prognosis of a CyTD responsive or non-responsive phenotype, comprising: (a) determining from a subject biological sample an expression profile comprising the gene MAPK14; or the genes MAPK14 and S100A9; or the genes MAPK14 and GNLY; or the 6 genes of Table 2, or the gene S100A9; or the genes S100A9, IL2RB, and CASP5; or the genes S100A9, IL2RB, KLRK1, HCK, and GNLY; or the genes S100A9, IL2RB, KLRK1, HCK, GNLY, CTSZ, ARF5, and UTP14C, or Equivalent Expression Profile of anyone of the expression profiles of (i) and (ii), and optionally one or more housekeeping gene(s), (b) comparing the obtained expression profile with at least one reference expression profile, and (c) determining the responsive or non-responsive phenotype from said comparison. The present invention also relates to kits and nucleic acid microarrays for performing said method, and methods of treatment of inflammatory disease-suffering patients.
    Type: Application
    Filed: March 24, 2011
    Publication date: April 18, 2013
    Applicant: TC LAND EXPRESSION
    Inventors: Alessandra Cervino, Oana Ruxandra Popa-Nita, Christophe Braud