Patents by Inventor Alessandra Frizzi
Alessandra Frizzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190249189Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.Type: ApplicationFiled: February 19, 2019Publication date: August 15, 2019Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
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Publication number: 20170356004Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.Type: ApplicationFiled: May 17, 2017Publication date: December 14, 2017Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
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Patent number: 9670502Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.Type: GrantFiled: January 25, 2013Date of Patent: June 6, 2017Assignee: Monsanto Technology LLCInventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
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Publication number: 20160264980Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency; enhanced cold tolerance, increased yield, enhanced-nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.Type: ApplicationFiled: January 29, 2016Publication date: September 15, 2016Inventors: Mark Scott Abad, Thomas R. Adams, Ameeta K. Agarwa, James A. Ball, Paolo Castiglioni, Banu Gopalan, Erin Bell, Shobha Char, Robert J. Bensen, Raghava S. Boddupalli, Alessandra Frizzi, Jill Deikman, Robert L. D'Ordine, Michael D. Edgerton, Xianfeng Chen, Mary Fernandes, Paul S. Chomet, Stephen Duff, Deborah G. Rucker, Changlin Fu, Jeffery E. Ahrens, Stanton B. Dotson, Richard E. Finger, Jinzhuo Dong, Molian Deng
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Patent number: 8455716Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.Type: GrantFiled: April 20, 2010Date of Patent: June 4, 2013Assignee: Monsanto Technology LLCInventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
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Patent number: 8299335Abstract: Novel corn opaque modifier loci, associated molecular markers and methods for obtaining the loci, markers, and resultant seed are provided. Vitreous seed with reduced alpha-zein storage protein content that contain the opaque modifier loci are also described. Processes for obtaining milled corn seed products from the vitreous seed with reduced alpha-zein storage protein content that contain the opaque modifier loci are also provided.Type: GrantFiled: March 30, 2009Date of Patent: October 30, 2012Assignee: Monsanto Technology LLCInventors: Thomas Malvar, Shihshieh Huang, Alessandra Frizzi, Mike Kerns
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Publication number: 20120227131Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.Type: ApplicationFiled: September 8, 2011Publication date: September 6, 2012Inventors: Mark S. Abad, Thomas R. Adams, Ameeta K. Argarwal, James A. Ball, Paolo Castiglioni, Banu Gopalan, Erin Bell, Shobha Char, Robert J. Bensen, Raghava S. Boddupalli, Alessandra Frizzi, Jill Deikman, Robert D'Ordine, Michael D. Edgerton, Xianfeng Chen, Mary Fernandes, Paul S. Chomet, Stephen Duff, Deborah G. Rucker, Changlin Fu, Jeffrey E. Ahrens, Stanton B. Dotson, Richard E. Finger, Jinzhuo Dong, Molian Deng
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Publication number: 20110035838Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: July 8, 2010Publication date: February 10, 2011Inventors: Linda Lutfiyya, Liang Guo, Philip W. Miller, Michael H. Luethy, Sara E. Heisel, Yuanji Zhang, Edwards Allen, Larry A. Gilbertson, David K. Kovalic, James K. Roberts, Shihshieh Huang, Alessandra Frizzi, Nancy Houmard, Thomas Malvar
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Publication number: 20110035839Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: July 8, 2010Publication date: February 10, 2011Inventors: Linda Lutfiyya, Liang Guo, Philip W. Miller, Michael H. Leuthy, Sara E. Heisel, Yuanji Zhang, Edwards Allen, Larry A. Gilbertson, David K. Kovalic, James K. Roberts, Shihshieh Huang, Alessandra Frizzi, Nancy Houmard, Thomas Malvar
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Publication number: 20100269224Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.Type: ApplicationFiled: April 20, 2010Publication date: October 21, 2010Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
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Publication number: 20100223694Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: March 18, 2010Publication date: September 2, 2010Inventors: Linda Lutfiyya, Liang Guo, Philip W. Miller, Michael H. Luethy, Sara E. Heisel, Yanji Zhang, Edwards Allen, Larry A. Gilbertson, David K. Kovalic, James K. Roberts, Shihshieh Huang, Alessandra Frizzi, Nancy Houmard, Thomas Malvar
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Patent number: 7723568Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: GrantFiled: October 10, 2006Date of Patent: May 25, 2010Assignee: Monsanto Technology LLCInventors: Linda Lutfiyya, Liang Guo, Philip W. Miller, Michael H. Luethy, Sara E. Heisel, Yuanji Zhang, Edwards Allen, Larry A. Gilbertson, David K. Kovalic, James K. Roberts, Shihshieh Huang, Alessandra Frizzi, Nancy Houmard, Thomas Malvar
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Publication number: 20090246350Abstract: Novel corn opaque modifier loci, associated molecular markers and methods for obtaining the loci, markers, and resultant seed are provided. Vitreous seed with reduced alpha-zein storage protein content that contain the opaque modifier loci are also described. Processes for obtaining milled corn seed products from the vitreous seed with reduced alpha-zein storage protein content that contain the opaque modifier loci are also provided.Type: ApplicationFiled: March 30, 2009Publication date: October 1, 2009Applicant: MONSANTO TECHNOLOGY LLCInventors: Thomas Malvar, Shihshieh Huang, Alessandra Frizzi, Mike Kerns
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Publication number: 20090013434Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: October 10, 2006Publication date: January 8, 2009Inventors: Shihshieh Huang, Thomas Malvar, Michael H. Luethy, Philip W. Miller, Larry A. Gilbertson, Edwards Allen, Sara E. Heisel, David K. Kovalic, James K. Roberts, Nancy Houmard, Alessandra Frizzi, Yuanji Zhang, Liang Guo, Linda Lutfiyya
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Publication number: 20080229456Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: October 10, 2006Publication date: September 18, 2008Inventors: Shihshieh Huang, Thomas Malvar, Michael H. Luethy, Philip W. Miller, Larry A. Gilbertson, Edwards Allen, Sara E. Heisel, David K. Kovalic, James K. Roberts, Nancy Houmard, Alessandra Frizzi, Yuanji Zhang, Liang Guo, Linda Lutfiyya
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Publication number: 20070094748Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: October 10, 2006Publication date: April 26, 2007Inventors: Shihshieh Huang, Thomas Malvar, Michael Luethy, Philip Miller, Larry Gilbertson, Edwards Allen, Sara Heisel, David Kovalic, James Roberts, Nancy Houmard, Alessandra Frizzi, Yuanji Zhang, Liang Guo, Linda Lutfiyya
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Publication number: 20070089185Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: October 10, 2006Publication date: April 19, 2007Inventors: Shihshieh Huang, Thomas Malvar, Michael Luethy, Philip Miller, Larry Gilbertson, Edwards Allen, Sara Heisel, David Kovalic, James Roberts, Nancy Houmard, Alessandra Frizzi, Yuanji Zhang, Liang Guo, Linda Lutfiyya
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Publication number: 20070089189Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: October 10, 2006Publication date: April 19, 2007Inventors: Shihshieh Huang, Thomas Malvar, Michael Luethy, Philip Miller, Larry Gilbertson, Edwards Allen, Sara Heisel, David Hovalic, James Roberts, Nancy Houmard, Alessandra Frizzi, Yuanji Zhang, Liang Guo, Linda Lutfiyya
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Publication number: 20070089190Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: October 10, 2006Publication date: April 19, 2007Inventors: Shihshieh Huang, Thomas Malvar, Michael Luethy, Philip Miller, Larry Gilbertson, Edwards Allen, Sara Heisel, David Kovalic, James Roberts, Nancy Houmard, Alessandra Frizzi, Yuanji Zhang, Liang Guo, Linda Lutfiyya
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Publication number: 20070089186Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: October 10, 2006Publication date: April 19, 2007Inventors: Shihshieh Huang, Thomas Malvar, Michael Luethy, Philip Miller, Larry Gilbertson, Edwards Allen, Sara Heisel, David Kovalic, James Roberts, Nancy Houmard, Alessandra Frizzi, Yuanji Zhang, Liang Guo, Linda Lutfiyya