Patents by Inventor Alessandra Mattei

Alessandra Mattei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COCRYSTALS OF UPADACITINIB
    Publication number: 20240043434
    Abstract: The disclosure relates to cocrystals of solid state forms of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide (Compound 1). Specifically, the present disclosure relates to cocrystals of Compound 1 and a suitable coformer, such as a substituted benzoic acid.
    Type: Application
    Filed: October 6, 2023
    Publication date: February 8, 2024
    Inventor: Alessandra Mattei
  • 2,2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof
    Patent number: 11873320
    Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
    Type: Grant
    Filed: August 6, 2021
    Date of Patent: January 16, 2024
    Assignee: REATA PHARMACEUTICALS HOLDINGS, LLC
    Inventors: Ahmad Y. Sheikh, Alessandra Mattei, Xiu C. Wang
  • 2,2-DIFLUOROPROPIONAMIDE DERIVATIVES OF BARDOXOLONE METHYL, POLYMORPHIC FORMS AND METHODS OF USE THEREOF
    Publication number: 20220073559
    Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
    Type: Application
    Filed: August 6, 2021
    Publication date: March 10, 2022
    Applicant: ABBVIE INC.
    Inventors: Ahmad Y. SHEIKH, Alessandra Mattei, Xiu C. WANG
  • 2,2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof
    Patent number: 11117927
    Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: September 14, 2021
    Inventors: Ahmad Y. Sheikh, Alessandra Mattei, Xiu C. Wang
  • 2,2-DIFLUOROPROPIONAMIDE DERIVATIVES OF BARDOXOLONE METHYL, POLYMORPHIC FORMS AND METHODS OF USE THEREOF
    Publication number: 20200062800
    Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
    Type: Application
    Filed: November 9, 2018
    Publication date: February 27, 2020
    Inventors: Ahmad Y. Sheikh, Alessandra Mattei, Xiu C. Wang
  • 2,2-DIFLUOROPROPIONAMIDE DERIVATIVES OF BARDOXOLONE METHYL, POLYMORPHIC FORMS AND METHODS OF USE THEREOF
    Publication number: 20180094020
    Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 5, 2018
    Inventors: Ahmad Y. Sheikh, Alessandra Mattei, Xiu C. Wang
  • 2,2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof
    Patent number: 9856286
    Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: January 2, 2018
    Assignee: AbbVie Inc.
    Inventors: Ahmad Y. Sheikh, Alessandra Mattei, Xiu C. Wang
  • 2,2-DIFLUOROPROPIONAMIDE DERIVATIVES OF BARDOXOLONE METHYL, POLYMORPHIC FORMS AND METHODS OF USE THEREOF
    Publication number: 20140323579
    Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
    Type: Application
    Filed: April 24, 2014
    Publication date: October 30, 2014
    Inventors: Ahmad Y. Sheikh, Alessandra Mattei, Xiu C. Wang