Patents by Inventor Alessandra Silvestri

Alessandra Silvestri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Treating or Preventing Gut Permeability-Related Disorders
    Publication number: 20220133771
    Abstract: Compositions and methods are provided for treating a gut permeability-related disease or disorder comprising administering to the gastrointestinal tract of a subject in need thereof, a therapeutically effective amount of a hydrogel having an elastic modulus (G?) of at least about 500 Pa.
    Type: Application
    Filed: October 14, 2021
    Publication date: May 5, 2022
    Inventors: Maria Rescigno, Alessandro Sannino, Yishai Zohar, Elaine Chiquette, Alessandra Silvestri, Christian Demitri
  • COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GUT PERMEABILITY-RELATED DISORDERS
    Publication number: 20200330502
    Abstract: Compositions and methods are provided for treating a gut permeability-related disease or disorder comprising administering to the gastrointestinal tract of a subject in need thereof, a therapeutically effective amount of a hydrogel having an elastic modulus (G?) of at least about 500 Pa.
    Type: Application
    Filed: January 27, 2020
    Publication date: October 22, 2020
    Inventors: Maria Rescigno, Alessandro Sannino, Yishai Zohar, Elaine Chiquette, Alessandra Silvestri, Christian Demitri
  • Compositions and methods for treating or preventing gut permeability-related disorders
    Patent number: 10695363
    Abstract: Compositions and methods are provided for treating a gut permeability-related disease or disorder comprising administering to the gastrointestinal tract of a subject in need thereof, a therapeutically effective amount of a hydrogel having an elastic modulus (G?) of at least about 500 Pa.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: June 30, 2020
    Assignee: Gelesis LLC
    Inventors: Maria Rescigno, Alessandro Sannino, Yishai Zohar, Elaine Chiquette, Alessandra Silvestri, Christian Demitri
  • COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GUT PERMEABILITY-RELATED DISORDERS
    Publication number: 20180333428
    Abstract: Compositions and methods are provided for treating a gut permeability-related disease or disorder comprising administering to the gastrointestinal tract of a subject in need thereof, a therapeutically effective amount of a hydrogel having an elastic modulus (G?) of at least about 500 Pa.
    Type: Application
    Filed: April 16, 2018
    Publication date: November 22, 2018
    Inventors: Maria Rescigno, Alessandro Sannino, Yishai Zohar, Elaine Chiquette, Alessandra Silvestri, Christian Demitri
  • SIGNAL PATHWAY ALTERATIONS AND DRUG TARGET ELEVATIONS IN PRIMARY METACHRONOUS METASTATIC COLORECTAL CANCER COMPARED TO NON-METASTATIC DISEASE
    Publication number: 20140030254
    Abstract: The present invention relates to the identification and diagnostic use of biomarkers in primary colorectal cancer tumors whose activation level are predictive of the likelihood of the onset of metastatic disease. These biomarkers may be used to determine the suitability of a patient for aggressive and/or targeted treatments. Kits and compositions of the invention are also provided.
    Type: Application
    Filed: March 27, 2013
    Publication date: January 30, 2014
    Inventors: Emanuel F. Petricoin, III, Lance A. Liotta, Mariaelena Pierobon, Alessandra Silvestri