Patents by Inventor Alessandro Baruto

Alessandro Baruto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF COLESEVELAM
    Publication number: 20160311941
    Abstract: The present invention relates to a new process for the synthesis of Colesevelam, which is used in therapy in cases of hypercholesterolemia due to low density lipoproteins. Said process comprises the reaction, in a basic environment, of polyallylamine with: i) at least one alkylating agent of formula X—(CH2)9—CH3 and at least one alkylating agent of formula Y—(CH2)6—N+ (CH3)3Z?, wherein X and Y are each independently a leaving group, and Z is a halogen; and ii) at least one crosslinking agent. The present invention also relates to the Colesevelam obtainable by the above process.
    Type: Application
    Filed: December 16, 2014
    Publication date: October 27, 2016
    Inventors: Mauro Gaboardi, Alessandro Baruto, Marta Castaldi
  • PROCESS AND INTERMEDIATES FOR THE PREPARATION OF DASATINIB
    Publication number: 20150259337
    Abstract: The present invention relates to a process for the synthesis of dasatinib and to intermediates useful for its preparation.
    Type: Application
    Filed: February 26, 2015
    Publication date: September 17, 2015
    Inventors: Alessandro BARUTO, Mauro GABOARDI, Marta CASTALDI, Graziano CASTALDI
  • Process and intermediates for the preparation of dasatinib
    Patent number: 9115124
    Abstract: The present invention relates to a process for the synthesis of dasatinib and to intermediates useful for its preparation.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: August 25, 2015
    Assignee: CERBIOS-PHARMA SA
    Inventors: Alessandro Baruto, Mauro Gaboardi, Marta Castaldi, Graziano Castaldi