Patents by Inventor Alessandro Bianchi

Alessandro Bianchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid encoding an altered telomere repeat binding factor
    Patent number: 6022709
    Abstract: The present invention provides an isolated altered vertebrate telomere repeat binding factor (A-TRF) that hinders the binding of a TRF to its specific telomere repeat sequence. Also included are the corresponding nucleic acids that encode the A-TRFs of the present invention, as well as the heterodimers formed by the association of an A-TRF with a TRF. In addition, pharmaceutical compositions containing the A-TRFs for treatment of diseases such as ataxia telangiectasia are also included. Methods of making, purifying and using the A-TRFs of the present invention are described. In addition, drug screening assays to identify drugs that mimic and/or complement the effect of the A-TRFs are presented.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: February 8, 2000
    Assignee: The Rockefeller University
    Inventors: Titia de Lange, Bas van Steensel, Alessandro Bianchi
  • Nucleic acid encoding an altered telomere repeat binding factor 2
    Patent number: 6020166
    Abstract: The present invention provides an isolated altered vertebrate telomere repeat binding factor (A-TRFs). Also included are the corresponding nucleic acids that encode the A-TRFs of the present invention, as well as the heterodimers formed by the association of an A-TRF with a TRF. In addition, pharmaceutical compositions containing the A-TRFs for treatment of diseases such as ataxia telangiectasia are also included. Methods of making, purifying and using the A-TRFs of the present invention are described. In addition, drug screening assays to identify drugs that mimic and/or complement the effect of the A-TRFs are presented.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: February 1, 2000
    Assignee: The Rockfeller University
    Inventors: Titia De Lange, Bas Van Steensel, Alessandro Bianchi
  • Altered telomere repeat binding factor 2
    Patent number: 5917019
    Abstract: The present invention provides an isolated altered vertebrate telomere repeat binding factor (A-TRFs). Also included are the corresponding nucleic acids that encode the A-TRFs of the present invention, as well as the heterodimers formed by the association of an A-TRF with a TRF. In addition, pharmaceutical compositions containing the A-TRFs for treatment of diseases such as ataxia telangiectasia are also included. Methods of making, purifying and using the A-TRFs of the present invention are described. In addition, drug screening assays to identify drugs that mimic and/or complement the effect of the A-TRFs are presented.
    Type: Grant
    Filed: February 4, 1998
    Date of Patent: June 29, 1999
    Assignee: The Rockefeller University
    Inventors: Titia de Lange, Bas Van Steensel, Alessandro Bianchi
  • Altered telomere repeat binding factor
    Patent number: 5859183
    Abstract: The present invention provides an isolated altered vertebrate telomere repeat binding factor (A-TRF) that hinders the binding of a TRF to its specific telomere repeat sequence. Also included are the corresponding nucleic acids that encode the A-TRFs of the present invention, as well as the heterodimers formed by the association of an A-TRF with a TRF. In addition, pharmaceutical compositions containing the A-TRFs for treatment of diseases such as ataxia telangiectasia are also included. Methods of making, purifying and using the A-TRFs of the present invention are described. In addition, drug screening assays to identify drugs that mimic and/or complement the effect of the A-TRFs are presented.
    Type: Grant
    Filed: February 13, 1997
    Date of Patent: January 12, 1999
    Assignee: The Rockefeller University
    Inventors: Titia de Lange, Bas van Steensel, Alessandro Bianchi
  • Distance-measuring method and transmitting and receiving station for carrying out the same
    Patent number: 5212534
    Abstract: In an optical communication system with a passive star coupler, measurement between a station and a central node should not interfere with the operation of other stations. Distance measurement is accomplished by determining the echo delay using a wavelength not being used by other stations. The system uses combined wavelength- and time-division multiplexing. One wavelength is always kept free for measurements if possible. For the measurement, the same data format as that employed during normal operation can be used. Measurement can be continuously repeated unchanged during operation.
    Type: Grant
    Filed: November 22, 1991
    Date of Patent: May 18, 1993
    Assignee: Alcatel N.V.
    Inventors: Alessandro Bianchi, Guiseppe Comito, Andrea Fantini