Abstract: Methods for identifying and quantifying recurrent and deterministic patterns in digital images are provided. The methods, which are based on Recurrence Quantification Analysis (RQA), generate similarity or dissimilarity distance matrices for digital images that may be used to calculate a variety of quantitative characteristics for the images. Also provided are methods for identifying and imaging spatial distributions of time variable signals generated from dynamic systems. In these methods a time variable signal is recorded for a plurality of area or volume elements into which a dynamic system has been sectioned and RQA is used to calculate one or more RQA variables for each of the area or volume elements, which may then be used to generate a two or three dimensional image displaying the spatial distribution of the RQA variables across the system.

Abstract: A tumor discriminator determines if a biological sample is diseaseous. Summarized expression value samples in a reference dataset are determined. The summarized expression value being a summation of gene expression levels for disease and normal samples. A biological sample summarized expression value is determined using a gene expression profile for a biological sample. A disease sample distance is estimated from the biological sample summarized expression value to a location in the disease sample space. The disease sample space defined by a statistical analysis of the disease samples. A normal sample distance is estimate from the biological sample summarized expression value to a location in the normal sample space The normal sample space defined by a statistical analysis of the normal samples. The disease sample distance is compared with the normal sample distance to determine if the biological sample is diseaseous.

Abstract: Methods for identifying and quantifying recurrent and deterministic patterns in digital images are provided. The methods, which are based on Recurrence Quantification Analysis (RQA), generate similarity or dissimilarity distance matrices for digital images that may be used to calculate a variety of quantitative characteristics for the images. Also provided are methods for identifying and imaging spatial distributions of time variable signals generated from dynamic systems. In these methods a time variable signal is recorded for a plurality of area or volume elements into which a dynamic system has been sectioned and RQA is used to calculate one or more RQA variables for each of the area or volume elements, which may then be used to generate a two or three dimensional image displaying the spatial distribution of the RQA variables across the system.

Abstract: Methods for identifying and quantifying recurrent and deterministic patterns in digital images are provided. The methods, which are based on Recurrence Quantification Analysis (RQA), generate similarity or dissimilarity distance matrices for digital images that may be used to calculate a variety of quantitative characteristics for the images. Also provided are methods for identifying and imaging spatial distributions of time variable signals generated from dynamic systems. In these methods a time variable signal is recorded for a plurality of area or volume elements into which a dynamic system has been sectioned and RQA is used to calculate one or more RQA variables for each of the area or volume elements, which may then be used to generate a two or three dimensional image displaying the spatial distribution of the RQA variables across the system.

Abstract: Methods for identifying and quantifying recurrent and deterministic patterns in digital images are provided. The methods, which are based on Recurrence Quantification Analysis (RQA), generate similarity or dissimilarity distance matrices for digital images that may be used to calculate a variety of quantitative characteristics for the images. Also provided are methods for identifying and imaging spatial distributions of time variable signals generated from dynamic systems. In these methods a time variable signal is recorded for a plurality of area or volume elements into which a dynamic system has been sectioned and RQA is used to calculate one or more RQA variables for each of the area or volume elements, which may then be used to generate a two or three dimensional image displaying the spatial distribution of the RQA variables across the system.