Patents by Inventor Alessandro Grattoni

Alessandro Grattoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOCHANNELED DEVICE WITH ELECTRODES AND RELATED METHODS
    Publication number: 20150088102
    Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, electrodes and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.
    Type: Application
    Filed: August 1, 2014
    Publication date: March 26, 2015
    Inventors: Daniel FINE, Alessandro GRATTONI, Mauro FERRARI, Xuewu LIU, Randal GOODALL, Sharath HOSALI
  • SUSTAINED DRUG DELIVERY FROM SOLID STATE COMPOSITIONS WITH NANOCHANNEL MEMBRANES
    Publication number: 20150032088
    Abstract: Implantable devices and methods for delivering pharmaceutical substances into a patient. The implantable device includes the following components: (a) an implant body, (b) a reservoir in the implant body, (c) a heterogeneous composition disposed in the reservoir, which includes a pharmaceutical substance in the solid state contacted by a solution of the pharmaceutical substance, and (d) a nanochannel membrane for delivering the pharmaceutical substance from the reservoir to a patient. Extended, high-quality delivery of low solubility drugs such as hormones and chemotherapeutic agents are achieved.
    Type: Application
    Filed: January 24, 2013
    Publication date: January 29, 2015
    Inventors: Alessandro Grattoni, Ganesh Subramanyam Palapattu, Mohit Khera
  • NANOCHANNELED DEVICE AND RELATED METHODS
    Publication number: 20140180251
    Abstract: A capsule configured for in vivo refilling of a therapeutic agent. In certain embodiments, the capsule may contain methotrexate.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 26, 2014
    Applicants: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION, THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Mauro Ferrari, Xuewu Liu, Alessandro Grattoni, Randy Goodall, Lee Hudson
  • Nanochanneled device and related methods
    Patent number: 8632510
    Abstract: A capsule configured for in vivo refilling of a thereapeutic agent. In certain embodiments, the capsule may contain methotrexate.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: January 21, 2014
    Assignees: The Board of Regents of the University of Texas System, The Ohio State University Research Foundation
    Inventors: Mauro Ferrari, Xuewu Liu, Alessandro Grattoni, Randy Goodall, Lee Hudson
  • NANOCHANNELED DEVICE AND RELATED METHODS
    Publication number: 20130240483
    Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.
    Type: Application
    Filed: May 2, 2013
    Publication date: September 19, 2013
    Applicants: The Ohio State University Research Foundation, The Board of Regents of the University of Texas System
    Inventors: Mauro FERRARI, Xuewu LIU, Alessandro GRATTONI, Daniel FINE, Randy GOODALL, Sharath HOSALI, Ryan MEDEMA, Lee HUDSON
  • Nanochanneled device and related methods
    Patent number: 8480637
    Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: July 9, 2013
    Assignees: The Board of Regents of the University of Texas System, The Ohio State University Research Foundation
    Inventors: Mauro Ferrari, Xuewu Liu, Alessandro Grattoni, Daniel Fine, Randy Goodall, Sharath Hosali, Ryan Medema, Lee Hudson
  • NANOCHANNELED DEVICE AND RELATED METHODS
    Publication number: 20130131629
    Abstract: Apparatus and methods of delivering a therapeutic agent using an implant comprising a nanochannel delivery device.
    Type: Application
    Filed: May 19, 2011
    Publication date: May 23, 2013
    Applicant: The Board of Regents of the Unversity of Texas System
    Inventors: Alessandro Grattoni, Aman P. Mann, Sharath Hosali, Randy Goodall, Lee Hudson
  • NANOCHANNELED DEVICE AND RELATED METHODS
    Publication number: 20120095443
    Abstract: A capsule configured for in vivo refilling of a thereapeutic agent. In certain embodiments, the capsule may contain methotrexate.
    Type: Application
    Filed: April 13, 2010
    Publication date: April 19, 2012
    Applicants: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Mauro Ferrari, Xuewu Liu, Alessandro Grattoni, Randy Goodall, Lee Hudson
  • QUALITY CONTROL METHOD AND MICRO/NANO-CHANNELED DEVICES
    Publication number: 20110137596
    Abstract: Embodiments of the present invention comprise a quality control system and method for testing micro- or nano-channeled devices. The system and method can utilize a pressure-driven gas flow for the detection and quantification of structural defects. The test method and system are non-destructive and allow defects to be detected and classified quickly based on measured factors, such as mass flow rate for a given pressure differential.
    Type: Application
    Filed: April 28, 2009
    Publication date: June 9, 2011
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Alessandro Grattoni, Mauro Ferrari, Xeuwu Liu
  • Nanochanneled Device and Related Methods
    Publication number: 20100152699
    Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.
    Type: Application
    Filed: November 13, 2009
    Publication date: June 17, 2010
    Applicants: The Board of Regents of the University of Texas System, The Ohio State University Research Foundation
    Inventors: Mauro Ferrari, Xuewu Liu, Alessandro Grattoni, Daniel Fine, Randy Goodall, Sharath Hosali, Ryan Medema, Lee Hudson