Abstract: A method is described for access to a directory by an application (410). A function library (412) handles a first request from the application for fetching the information from a server. The first request is forwarded from the function library (412) to the server by a client module (414). A request identifier (420) is sent from the function library to the application when the first request is forwarded to the server. A response signal (422) to the first request is sent from the server and received by the application. The response signal comprises a response identifier. The response identifier is checked to match the response signal (422) to the first request. A function from the function library is called (424) by the application for decoding the response signal. The decoded response signal is returned (426) from the function library to the application. A device and a program are also described.

Abstract: A method is described for access to a directory by an application (410). A function library (412) handles a first request from the application for fetching the information from a server. The first request is forwarded from the function library (412) to the server by a client module (414). A request identifier (420) is sent from the function library to the application when the first request is forwarded to the server. A response signal (422) to the first request is sent from the server and received by the application. The response signal comprises a response identifier. The response identifier is checked to match the response signal (422) to the first request. A function from the function library is called (424) by the application for decoding the response signal. The decoded response signal is returned (426) from the function library to the application. A device and a program are also described.

Abstract: A multilayer necktie consisting of a first portion of fabric defined by three sections joined together without continuity solution to define: a so-called blade of the necktie, standing, when used, in sight of the user; the part around the user's neck; another blade, standing, when the necktie is knotted according to preferable manner, behind the first section and one destined to be partly showing, since it is as wide as, or preferably wider than, the first section. A second portion of fabric is superimposed on this first portion of fabric, which is joined or joinable to the first portion by means of relevant attachments. The resulting necktie is characterized in that, once knotted around the user's neck so as to show, at least partly, three blades, it features a knot in which at least two portions of fabric can be seen.

Abstract: A multilayer necktie (1) consisting of a first portion of fabric (P) defined by three sections (2, 3, 4) joined together without continuity solution to define: a so-called blade of the necktie (2), standing, when used, in sight of the user; the part around the user's neck (3); another blade (4), standing, when the necktie is knotted according to a preferable manner, behind the first section (2) and one destined to be partly showing, since it is as wide as, or preferably wider than, the first section (2). A second portion of fabric (6) is superimposed on this first portion (P) of fabric, which is joined or joinable to the first portion (P) by means of relevant attachments (7). The resulting necktie is characterized in that, once knotted around the user's neck so as to show, at least partly, three blades (4, 2, 6a), it features a knot (5) in which at least two portions of fabric (St1, St2) can be seen.

Abstract: The present invention refers to conjugated compounds of antiviral drugs having hepatotropic activity, methods of making these compounds, and compositions thereof.

Abstract: The present invention refers to conjugated compounds of antiviral drugs having hepatotropic activity, methods of making these compounds, and compositions thereof.

Abstract: A conjugate of an antiviral nucleoside with a lactosaminated human albumin (L-HSA) and its method of preparation is described. The method of preparation involves the reaction of an antiviral phosphorylated nucleoside in the form of an imidizolide with L-HSA at a pH above 7.5 and running the reaction until the desired molar ratio of drug to L-HSA is obtained.

Abstract: For the preparation of conjugates of adenine-9-beta-D-arabinofuranoside 5'monophosphate (ara-AMP) with lactosaminated human albumin (L-HSA) aqueous solutions of the two components to be conjugated are brought into contact in the presence of 1-ethyl-3-(dimethylaminopropyl)-carbodiimide, by adjusting the pH in the range from slightly acidic to alkaline and by carrying out the conjugate separation. The resulting conjugate, wherein the molar ratio, as determined through spectrophotometric route, between ara-AMP and L-HSA does vary between 5 and 20, remains soluble after lyophilization even at room temperature and shows biological activity at least equivalent to that of the conjugate as prepared according to the known art.

Abstract: A conjugate of 9-(2-hydroxyethoxymethyl)-guanine with lactosaminated human albumin is therapeutically more efficacious than the free drug in the treatment of chronical hepatitis induced from Virus B. For the preparation of the conjugate an aqueous solution of 9-(2-hydroxyethoxymethyl)-guanine in form of a derivative, particularly monophosphate, and an aqueous solution of lactosaminated human albumin are reacted in the presence of 1-ethyl-3-(dimethylaminopropyl)-carbodiimide, by adjusting the pH to the value of 7.5 and by maintaining the reaction mixture for 24 hours under stirring and in the dark.