Abstract: A positioning device for deploying at least one locking portion (20) of an anastomotic device (10) for drawing together a first tissue portion (12) and a second tissue portion (14) to be connected by means of anastomosis is suitable for sliding along a guide means comprising at least one guide wire (A, B) and comprises an elongated structure (50). A head (52) of the positioning device is suitable to be interference-inserted on a distal end of the elongated structure (50). The head (52) comprises elastic tabs (54) extending from a proximal end of the head and at least one channel (56) suitable for receiving a guide wire. The head (52) comprises a distal end defining a thrust surface (58) for a locking portion (20) of the anastomotic device (10).

Abstract: A surgical instrument (1) for performing controlled myotomies, particularly for performing internal anal sphincterotomies, comprises a proximal handle portion (2), an elongate insertion shaft (3) connected with the handle portion (2) and extending distally therefrom, a distal incision tip (4) arranged at a distal end of the insertion shaft (3) and adapted to incise tissue distally to the insertion shaft (3), a lateral incision member (5) arranged at the insertion shaft (3) and adapted to incise tissue laterally to the insertion shaft (3), wherein the lateral incision member (4) is movable from a rest position, in which it is retracted towards or inside the insertion shaft (3) and an operational position in which it protrudes laterally from the insertion shaft (3).

Abstract: A surgical stapling instrument (1) comprises a staple fastening assembly (4) in the distal region of said instrument, the staple fastening assembly (4) including a cartridge device (8) which comprises at least one closed row (17, 18) of staples and defines a wavy distal end surface (14), and an anvil (9) which defines a wavy proximal staple forming surface (20) substantially matching the distal end surface (14) and which is adapted to cooperate with the cartridge device (8) for forming the ends of the staples exiting from the cartridge device (8), wherein the distal end surface (14) and the staple forming surface (20) have a globally wavy shape including two opposite peaks (21) and two opposite valleys (22) angularly spaced at about 90° from the adjacent peaks (21) and in that said two-peaks-two-valleys wavy shape is formed by a stepped configuration of said surfaces (14, 20).

Abstract: Traction means (14) for excising a tissue sample comprising a distal portion (14a), comprising at least one clip (20) suitable for being fixed to at least one portion (12) of tissue to be excised and a proximal portion (14b) suitable for being subjected to traction. Said at least one clip (20) is suitable for being connected to a distal end (22a) of a suture (22) to pull the tissue to be excised, said suture (22) extending between said distal end (22a) and a proximal end corresponding to the proximal portion of said traction means (14). Moreover, said at least one clip (20) is connected to a ring (24) formed at a distal end (24a) of said suture (22) to pull the tissue to be excised.

Abstract: An Instrumentation for performing an endoluminal or transluminal anastomosis, comprises an anastomotic ring device including a proximal ring (5) having two guide wire seats (22) adapted to slidably receive two guide wires (1, 2) and a distal ring (6) having two guide wire seats (25) adapted to slidably receive the two guide wires, the proximal ring and the distal ring being snap-connectable to each other, a surgical probe (7) comprising an elongate insertion shaft (30) and a probe head (32) adapted to be endoluminally advanced to a proximal tissue portion (3), the insertion shaft defining guide wire canals (8, 9) extending into two guide wire exit openings (31) defined in the probe head and adapted to deliver the distal ends (1?, 2?) of said guide wires to said proximal tissue portion.

Abstract: A surgical stapling instrument comprises a staple fastening assembly (1, 5; 24) including a cartridge device (5; 30) which comprises at least one row of staples (72, 77) and a generally wavy first tissue interface (34), and an anvil (1; 32) which is movable relative to the cartridge device (5; 30) and having a generally wavy second tissue interface (36) adapted to cooperate with the first tissue interface (34) of the cartridge device (5; 30) for clamping tissue therebetween and forming the ends (74) of the staples (72, 77) exiting from the cartridge device (5; 30), a staple driving device (60; 90) adapted to drive the staples (72, 77) out of the cartridge device (5; 30) towards the anvil (1; 32), wherein the staples comprise one or more non-symmetrical U-shaped staples (77) having two legs (78) with free pointed ends (74) facing toward the anvil (1; 32) and a transverse basis (79) connecting the legs (78), wherein said basis (79) is inclined with respect to the longitudinal direction (81) of the legs (78), su

Abstract: A surgical instrument including a firing drive configured to selectively advance a firing member and/or cutting member relative to an end effector and, in addition, a reversing drive configured to selectively retract the firing member and/or cutting member relative to the end effector.

Abstract: A device for the intraluminal treatment of tissue comprises a handle, a shaft which extends from the handle and a head arranged at the distal end of the shaft, wherein the head comprises at least one jaw, movable between an open position, wherein it defines a window for the insertion of the tissue and surrounding tissue, and a closed position, and wherein the shaft extends between the handle and head in a curvilinear longitudinal direction.

Abstract: A surgical stapling instrument (1) comprises a staple fastening assembly (4) in the distal region of said instrument, the staple fastening assembly (4) including a cartridge device (8) which comprises at least one closed row (17, 18) of staples and defines a wavy distal end surface (14), and an anvil (9) which defines a wavy proximal staple forming surface (20) substantially matching the distal end surface (14) and which is adapted to cooperate with the cartridge device (8) for forming the ends of the staples exiting from the cartridge device (8), wherein the distal end surface (14) and the staple forming surface (20) have a globally wavy shape including two opposite peaks (21) and two opposite valleys (22) angularly spaced at about 90° from the adjacent peaks (21) and in that said two-peaks-two-valleys wavy shape is formed by a stepped configuration of said surfaces (14, 20).

Abstract: An equipment to approximate tissue portions, which are intended to form an anastomosis comprises a guide means suitable for passing through a first tissue portion (12) and a second tissue portion (14) to be connected by anastomosis. This equipment further comprises an anastomotic device (10) to approximate the first tissue portion (12) and the second tissue portion (14) to be connected by anastomosis. The guide means consists of at least two guide wires (A, B), suitable for passing through the tissue portions to be connected, to receive and drag at least said anastomotic device (10) to approximate the first tissue portion (12) and the second tissue portion (14) to be connected by anastomosis. The guide wires (A, B) are located side by side to each other and are suitable for forming a loop which passes through the tissue portions to be connected.

Abstract: 1. Instrumentation for carrying out a gastrointestinal bypass comprising: means (4, 6, 12) for creating a gastric sleeve (21, 22) from the lesser curvature (13) of the stomach (1), means for creating a gastrointestinal bypass involving said gastric sleeve (21, 22), in which said means for creating a gastrointestinal bypass include: means for creating a gastroenteroanastomosis (26) between two closely approximated gastric and intestinal tissue portions, maintaining the continuity of the intestinal duct after the creation of the gastroenteroanastomosis, means for creating an enteroenteroanastomosis (29) between two closely approximated tissue portions (27, 28) of the intestine, maintaining the continuity of the intestinal duct after the creation of the enteroenteroanastomosis (29), means for sectioning the intestine (20) between the gastroenteroanastomosis (26) and the enteroenteroanastomosis (29).

Abstract: A method for regulating hormone production comprises placing at least one electrode in a gastrointestinal tract of a patient and recording an electrical signal during a preselected event produced by the gastrointestinal tract. The method further involves the steps of storing the electrical signal, and playing back the electrical signal by activating the electrode during the absence of the preselected event.

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.

Abstract: Methods described herein involve introducing a nasogastric tube into a patient, connecting the nasogastric tube with a reservoir, anchoring the nasogastric tube with the nasal cavity, and introducing a substance into the reservoir through the nasogastric tube.

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.

Abstract: Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may comprise one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.

Abstract: The present invention generally provides for a catheter for surgically treating a patient. The catheter has an inlet catheter having a proximal end and an open distal end, and first and second branch sections having proximal ends attached to the open distal end of the inlet lumen. The first and second branch sections and distal ends terminating at an open proximal end of an outlet lumen. The first passageway lumen has a device for deactivating at least a portion of the digestive enzymes in an amount of bile.

Abstract: The present invention generally provides for a method of treating metabolic disorder by severing a bile duct from fluid communication with an intestine at a first target site adjacent the Oddi sphincter, thereby creating a severed bile duct. The method further involves re-establishing fluid communication of the severed bile duct with the intestine by attaching a distal end of the severed bile duct to a second target site along the intestine, wherein said second target site is distal to the first target site.

Abstract: The present invention generally provides for correcting an imbalance between caloric intake and caloric expenditure in patients, as well as for treating co-morbidities often associated therewith, which is non-invasive or minimally invasive and which may be reversible. More specifically, the present invention provides systems which cause metabolic improvement in a patient by controlling the amount of bile available for food breakdown or by controlling the effective absorption time and area by delivering bile to selected locations in the intestinal tract. These methods and devices fall under three general categories: bile diversion systems, bile manipulation systems, and surgical methods.