Patents by Inventor Alessandro Rastrelli

Alessandro Rastrelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6897203
    Abstract: The present invention relates to polysaccharidic esters of retinoic acid, wherein the hydroxyl groups of the monosaccharidic units of the polysaccharide are partially or totally esterified with retinoic acid. A process to obtain these esters is also described. The products according to the present invention can be used in the pharmaceutical and cosmetic field.
    Type: Grant
    Filed: January 16, 2002
    Date of Patent: May 24, 2005
    Assignee: Eurand Pharmaceuticals Ltd.
    Inventors: Alessandro Rastrelli, Giuliana Miglierini, Alberto Perbellini, Luca Stucchi
  • Publication number: 20050065112
    Abstract: The present invention is related to polysaccharide esters of N-derivatives of glutamic acid (N-GA derivatives). These polysaccharidic esters have antiproliferative activity and are characterized by a low systemic toxicity. The esters of the invention are used in the prevention and therapy of diseases caused by cellular hyperproliferation, particularly psoriasis, tumors, rheumatoid arthritis, or intestinal inflammatory pathologies.
    Type: Application
    Filed: September 27, 2004
    Publication date: March 24, 2005
    Inventors: Giuliana Miglierini, Luca Stucchi, Alessandro Rastrelli
  • Patent number: 6844328
    Abstract: The present invention is related to polysaccharide esters of N-derivatives of glutamic acid (N-GA derivatives). These polysaccharidic esters have antiproliferative activity and are characterized by a low systemic toxicity. The esters of the invention are used in the prevention and therapy of diseases caused by cellular hyperproliferation, particularly psoriasis, tumors, rheumatoid arthritis, or intestinal inflammatory pathologies.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: January 18, 2005
    Assignee: Eurand Pharmaceuticals Ltd.
    Inventors: Giuliana Miglierini, Luca Stucchi, Alessandro Rastrelli
  • Publication number: 20040171580
    Abstract: The present invention describes a class of new regioselectively reticulated polysaccharides. A process to obtain these polysaccharides, starting from naturally occurring, possibly substituted polysaccharides, is also described. The products can be used in the medical filed and in other industrial sectors.
    Type: Application
    Filed: December 10, 2003
    Publication date: September 2, 2004
    Inventors: Luca Stucchi, Alessandro Rastrelli
  • Publication number: 20040171581
    Abstract: The present invention relates to polysaccharidic esters of retinoic acid, wherein the hydroxyl groups of the monosaccharidic units of the polysaccharide are partially or totally esterified with retinoic acid. A process to obtain these esters is also described. The products according to the present invention can be used in the pharmaceutical and cosmetic field.
    Type: Application
    Filed: January 14, 2004
    Publication date: September 2, 2004
    Inventors: Alessandro Rastrelli, Giuliana Miglierini, Alberto Perbellini, Luca Stucchi
  • Publication number: 20030158125
    Abstract: The present invention is related to polysaccharide esters of N-derivatives of glutamic acid (N-GA derivatives). These polysaccharidic esters have antiproliferative activity and are characterized by a low systemic toxicity. The esters of the invention are used in the prevention and therapy of diseases caused by cellular hyperproliferation, particularly psoriasis, tumors, rheumatoid arthritis, or intestinal inflammatory pathologies.
    Type: Application
    Filed: January 27, 2003
    Publication date: August 21, 2003
    Inventors: Giuliana Miglierini, Luca Stucchi, Alessandro Rastrelli
  • Patent number: 5709877
    Abstract: This invention provides new gels in the form of highly hydrated self-supporting film, comprising one or more alkaline alginates, an alkaline earth alginate, a polyalcohol and a natural, synthetic or semisynthetic polymer of hydrophilic nature, and their preparation process. These polysaccharide-matrix gels in highly hydrated self-supporting film form are suitable for use as covering and protection materials for cutaneous lesions and/or pathologies in that they are obtainable in self-supporting form in the desired thickness, are transparent, flexible, have good mechanical characteristics, are adaptable to the lesion surface without strongly adhering to it, and are permeable to gas but are impermeable to liquids and bacteria; one or more pharmacologically active substances can also be incorporated in the gel.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 20, 1998
    Assignee: Fidia S.p.A.
    Inventors: Francesco Della Valle, Alessandro Rastrelli, Gabriella Calderini, Aurelio Romeo
  • Patent number: 5658331
    Abstract: The invention relates to biocompatible membranes constructed of materials of natural, synthetic or semisynthetic origin, and having a thickness of between 10 and 500.mu., characterized by containing an ordered series of holes of a constant size between 10 and 1000.mu., separated from each other by a constant distance of between 50 and 1000.mu., and obtained by perforation by mechanical, thermal laser or ultraviolet radiation means, they being suitable for use as a support for the in vitro growth of epithelial cells, the invention also relating to the artificial skin obtained thereby and its use in grafts.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 19, 1997
    Assignee: Fidia S.P.A.
    Inventors: Francesco Della Valle, Gabriella Calderini, Alessandro Rastrelli, Aurelio Romeo
  • Patent number: 5650164
    Abstract: The invention relates to biocompatible membranes constructed of materials of natural, synthetic or semisynthetic origin, and having a thickness of between 10 and 500 .mu., characterised by containing an ordered series of holes of a constant size between 10 and 1000 .mu., separated from each other by a constant distance of between 50 and 1000 .mu., and obtained by perforation by mechanical, thermal laser or ultraviolet radiation means, they being suitable for use as a support for the in vitro growth of epithelial cells, the invention also relating to the artificial skin obtained thereby and its use in grafts.
    Type: Grant
    Filed: March 14, 1994
    Date of Patent: July 22, 1997
    Assignee: Fidia S.p.A.
    Inventors: Francesco Della Valle, Gabriella Calderini, Alessandro Rastrelli, Aurelio Romeo
  • Patent number: 5618561
    Abstract: This invention provides new gels in the form of highly hydrated self-supporting film, comprising one or more alkaline alginates, an alkaline earth alginate, a polyalcohol and a hyaluronic acid or a derivative thereof, and their preparation process. These polysaccharide-matrix gels in highly hydrated self-supporting film form are suitable for use as covering and protection materials for cutaneous lesions and/or pathologies in that they are obtainable in self-supporting form in the desired thickness, are transparent, flexible, have good mechanical characteristics, are adaptable to the lesion surface without strongly adhering to it, and are permeable to gas but are impermeable to liquids and bacteria; one or more pharmacologically active substances can also be incorporated in the gel.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 8, 1997
    Assignee: Fidia S.p.A.
    Inventors: Francesco Della Valle, Alessandro Rastrelli, Gabriella Calderini, Aurelio Romeo
  • Patent number: 5523093
    Abstract: This invention provides new gels in the form of highly hydrated self-supporting film, comprising one or more alkaline alginates, an alkaline earth alginate, a polyalcohol and a natural, synthetic or semisynthetic polymer of hydrophilic nature, and their preparation process. These polysaccharide-matrix gels in highly hydrated self-supporting film form are suitable for use as covering and protection materials for cutaneous lesions and/or pathologies in that they are obtainable in self-supporting form in the desired thickness, are transparent, flexible, have good mechanical characteristics, are adaptable to the lesion surface without strongly adhering to it, and are permeable to gas but are impermeable to liquids and bacteria; one or more pharmacologically active substances can also be incorporated in the gel.
    Type: Grant
    Filed: May 30, 1991
    Date of Patent: June 4, 1996
    Assignee: Fidia, S.p.A.
    Inventors: Francesco Della Valle, Alessandro Rastrelli, Gabriella Calderini, Aurelio Romeo
  • Patent number: 5326356
    Abstract: It is provided biocompatible membranes constructed of materials of natural, synthetic or semisynthetic origin, and having a thickness of between 10 and 500.mu., characterised by containing an ordered series of holes of a constant size between 10 and 1000.mu., separated from each other by a constant distance of between 50 and 1000.mu., and obtained by perforation by mechanical, thermal laser or ultraviolet radiation means, they being suitable for use as a support for the in vitro growth of epithelial cells. Artificial skins obtained thereby and its use in grafts are also provided.
    Type: Grant
    Filed: February 16, 1993
    Date of Patent: July 5, 1994
    Assignee: Fidia S.p.A.
    Inventors: Francesco Della Valle, Gabriella Calderini, Alessandro Rastrelli, Aurelio Romeo