Patents by Inventor Alessandro Surace

Alessandro Surace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240123127
    Abstract: A control unit of an apparatus for extracorporeal blood treatment is configured to perform a control procedure comprising: calculating parameter control values to be set during a time interval after the instant in which the control is made, on the basis of actual values and of prescription values of variation in blood volume, ultrafiltration flow rate, concentration of sodium and/or potassium and heart rate or variation of heart rate of the patient; imposing the parameter control values during the time interval consecutive to the instant in which the control is made such that the actual values of the variation in blood volume track the prescription values of the variation in blood volume over a predetermined treatment time and the actual values of the heart rate or variation of heart rate track the prescription values of the heart rate or variation of heart rate over the predetermined treatment time.
    Type: Application
    Filed: February 10, 2022
    Publication date: April 18, 2024
    Inventors: Paolo Rovatti, Alessandro Surace
  • Patent number: 11883571
    Abstract: An extracorporeal blood treatment apparatus includes a filtration unit (2) connected to a blood circuit (17) and a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating of the dialysis fluid up to the calculating of the initial plasma conductivity performed by maintaining the dialysis fluid conductivity substantially constant.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: January 30, 2024
    Assignee: Gambro Lundia AB
    Inventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
  • Patent number: 11426501
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: August 30, 2022
    Assignee: Gambro Lundia AB
    Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
  • Patent number: 11383012
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: July 12, 2022
    Assignee: Gambro Lundia AB
    Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
  • Publication number: 20220096719
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit connected to a blood circuit and to a dialysate circuit, a preparation device for preparing and regulating the composition of the dialysis fluid; a control unit is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line at a set point based on the physician prescription; starting from the initial patient plasma conductivity, estimated at the beginning of the treatment, and based on the target plasma conductivity/sodium concentration which is equivalent to the dialysate conductivity/sodium concentration prescribed, the control unit determines the minimum constant gradient between dialysis fluid and plasma conductivity/concentration to be maintained during treatment to achieve the conductivity/concentration target in the patient plasma at the end of the session.
    Type: Application
    Filed: December 27, 2019
    Publication date: March 31, 2022
    Inventors: Paolo ROVATTI, Alessandro SURACE, Carlo Alberto LODI
  • Publication number: 20200237990
    Abstract: An extracorporeal blood treatment apparatus includes a filtration unit (2) connected to a blood circuit (17) and a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating of the dialysis fluid up to the calculating of the initial plasma conductivity performed by maintaining the dialysis fluid conductivity substantially constant.
    Type: Application
    Filed: April 15, 2020
    Publication date: July 30, 2020
    Inventors: Paolo ROVATTI, Alessandro SURACE, Carlo Alberto LODI, Anders WALLENBORG, Anders NILSSON, Kristian SOLEM, Jan STERNBY, Thomas HERTZ
  • Patent number: 10646632
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: May 12, 2020
    Assignee: GAMBRO LUNDIA AB
    Inventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
  • Publication number: 20190374697
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.
    Type: Application
    Filed: October 27, 2017
    Publication date: December 12, 2019
    Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
  • Patent number: 10485912
    Abstract: A method of operating an extracorporeal blood treatment includes, prior to commencing an extracorporeal blood treatment, reading from a storage device (4a, 5a) stored values of a patient-specific prescription parameter. These stored values relate to a sequence of previous extracorporeal blood treatments. In addition, the method includes processing the stored values of the parameter read from the storage device (4a, 5a) according to a predetermined algorithm to determine a current value of the patient-specific prescription parameter. The current value is then available for the subsequent extracorporeal blood treatment.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: November 26, 2019
    Assignee: Gambro Lundia AB
    Inventors: Paolo Rovatti, Alessandro Surace
  • Patent number: 10434236
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: October 8, 2019
    Assignee: Gambro Lundia AB
    Inventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
  • Publication number: 20190275230
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.
    Type: Application
    Filed: October 26, 2017
    Publication date: September 12, 2019
    Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
  • Patent number: 10265459
    Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: April 23, 2019
    Assignee: GAMBRO LUNDIA AB
    Inventors: Francesco Fontanazzi, Alessandro Surace, Francesco Rosati
  • Publication number: 20180193547
    Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.
    Type: Application
    Filed: March 5, 2018
    Publication date: July 12, 2018
    Inventors: Francesco Fontanazzi, Alessandro Surace, Francesco Rosati
  • Publication number: 20180169315
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.
    Type: Application
    Filed: May 23, 2016
    Publication date: June 21, 2018
    Inventors: Paolo ROVATTI, Alessandro SURACE, Cario Alberto LODI, Anders WALLENBORG, Anders NILLSON, Kristian SOLEM, Jan STERNBY, Thomas HERTZ
  • Publication number: 20180140761
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.
    Type: Application
    Filed: May 23, 2016
    Publication date: May 24, 2018
    Inventors: Paolo Rovatti, Alessandro Surace, Cario Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
  • Patent number: 9943636
    Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: April 17, 2018
    Assignee: GAMBRO LUNDIA AB
    Inventors: Francesco Fontanazzi, Alessandro Surace, Francesco Rosati
  • Patent number: 9925321
    Abstract: It is disclosed an apparatus for extracorporeal blood treatment (1) having a control unit (15) connected to an ultrafiltration device (20) and to a fluid preparation section (30) of fresh dialysis liquid. The control unit (15) is configured to receive measured values of the change of blood volume, the amount of ultrafiltration volume, and conductivity or to the concentration for at least one substance in the blood (BV %mes(t); UFmes(t), WLmes(t); Cbmes(t)); the control unit (15) is also configured to receive prescription values for the same parameters and to control ultrafiltration and adjust conductivity in the fresh dialysis liquid based on the difference between said measured values and said prescription values.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: March 27, 2018
    Assignee: Gambro Lundia AB
    Inventors: Alessandro Surace, Paolo Rovatti
  • Publication number: 20160303303
    Abstract: A method of operating an extracorporeal blood treatment includes, prior to commencing an extracorporeal blood treatment, reading from a storage device (4a, 5a) stored values of a patient-specific prescription parameter. These stored values relate to a sequence of previous extracorporeal blood treatments. In addition, the method includes processing the stored values of the parameter read from the storage device (4a, 5a) according to a predetermined algorithm to determine a current value of the patient-specific prescription parameter. The current value is then available for the subsequent extracorporeal blood treatment.
    Type: Application
    Filed: December 10, 2014
    Publication date: October 20, 2016
    Applicant: Gambro Lundia AB
    Inventors: Paolo ROVATTI, Alessandro SURACE
  • Patent number: 9220830
    Abstract: An apparatus for extracorporeal blood treatment including a treatment unit; an extracorporeal blood circuit; an infusion line of a replacement fluid; a dialysis line connected in inlet to the second chamber; a fluid evacuation line; sensors for determining a first parameter relating to a patient's blood volume (BV %), a second parameter relating to an ultrafiltration flow rate (UFR) or to a patient's weight loss rate (WLR), a third parameter (Cd, Na) relating to a conductivity or concentration of a liquid crossing the dialysis line and/or the infusion line, and a fourth parameter relating to an infusion flow rate (QINF), and a control unit performing a control procedure to determine a variation in blood volume (BV %) and perform a setting sequence, wherein the control unit regulates a transmembrane pressure (TMP) to values which enable maximizing the convective exchanges.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: December 29, 2015
    Assignee: GAMBRO DASCO S.P.A.
    Inventors: Francesco Fontanazzi, Alessandro Surace, Francesco Paolini
  • Publication number: 20150343129
    Abstract: It is disclosed an apparatus for extracorporeal blood treatment (1) having a control unit (15) connected to an ultrafiltration device (20) and to a fluid preparation section (30) of fresh dialysis liquid. The control unit (15) is configured to receive measured values of the change of blood volume, the amount of ultrafiltration volume, and conductivity or to the concentration for at least one substance in the blood (BV %mes(t); UFmes(t), WLmes(t); Cbmes(t)); the control unit (15) is also configured to receive prescription values for the same parameters and to control ultrafiltration and adjust conductivity in the fresh dialysis liquid based on the difference between said measured values and said prescription values.
    Type: Application
    Filed: December 16, 2013
    Publication date: December 3, 2015
    Inventors: Alessandro Surace, Paolo Rovatti