Patents by Inventor Alessandro Surace
Alessandro Surace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240123127Abstract: A control unit of an apparatus for extracorporeal blood treatment is configured to perform a control procedure comprising: calculating parameter control values to be set during a time interval after the instant in which the control is made, on the basis of actual values and of prescription values of variation in blood volume, ultrafiltration flow rate, concentration of sodium and/or potassium and heart rate or variation of heart rate of the patient; imposing the parameter control values during the time interval consecutive to the instant in which the control is made such that the actual values of the variation in blood volume track the prescription values of the variation in blood volume over a predetermined treatment time and the actual values of the heart rate or variation of heart rate track the prescription values of the heart rate or variation of heart rate over the predetermined treatment time.Type: ApplicationFiled: February 10, 2022Publication date: April 18, 2024Inventors: Paolo Rovatti, Alessandro Surace
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Patent number: 11883571Abstract: An extracorporeal blood treatment apparatus includes a filtration unit (2) connected to a blood circuit (17) and a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating of the dialysis fluid up to the calculating of the initial plasma conductivity performed by maintaining the dialysis fluid conductivity substantially constant.Type: GrantFiled: April 15, 2020Date of Patent: January 30, 2024Assignee: Gambro Lundia ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Patent number: 11426501Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: GrantFiled: October 27, 2017Date of Patent: August 30, 2022Assignee: Gambro Lundia ABInventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Patent number: 11383012Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: GrantFiled: October 26, 2017Date of Patent: July 12, 2022Assignee: Gambro Lundia ABInventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Publication number: 20220096719Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit connected to a blood circuit and to a dialysate circuit, a preparation device for preparing and regulating the composition of the dialysis fluid; a control unit is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line at a set point based on the physician prescription; starting from the initial patient plasma conductivity, estimated at the beginning of the treatment, and based on the target plasma conductivity/sodium concentration which is equivalent to the dialysate conductivity/sodium concentration prescribed, the control unit determines the minimum constant gradient between dialysis fluid and plasma conductivity/concentration to be maintained during treatment to achieve the conductivity/concentration target in the patient plasma at the end of the session.Type: ApplicationFiled: December 27, 2019Publication date: March 31, 2022Inventors: Paolo ROVATTI, Alessandro SURACE, Carlo Alberto LODI
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Publication number: 20200237990Abstract: An extracorporeal blood treatment apparatus includes a filtration unit (2) connected to a blood circuit (17) and a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating of the dialysis fluid up to the calculating of the initial plasma conductivity performed by maintaining the dialysis fluid conductivity substantially constant.Type: ApplicationFiled: April 15, 2020Publication date: July 30, 2020Inventors: Paolo ROVATTI, Alessandro SURACE, Carlo Alberto LODI, Anders WALLENBORG, Anders NILSSON, Kristian SOLEM, Jan STERNBY, Thomas HERTZ
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Patent number: 10646632Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: GrantFiled: May 23, 2016Date of Patent: May 12, 2020Assignee: GAMBRO LUNDIA ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Publication number: 20190374697Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: ApplicationFiled: October 27, 2017Publication date: December 12, 2019Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Patent number: 10485912Abstract: A method of operating an extracorporeal blood treatment includes, prior to commencing an extracorporeal blood treatment, reading from a storage device (4a, 5a) stored values of a patient-specific prescription parameter. These stored values relate to a sequence of previous extracorporeal blood treatments. In addition, the method includes processing the stored values of the parameter read from the storage device (4a, 5a) according to a predetermined algorithm to determine a current value of the patient-specific prescription parameter. The current value is then available for the subsequent extracorporeal blood treatment.Type: GrantFiled: December 10, 2014Date of Patent: November 26, 2019Assignee: Gambro Lundia ABInventors: Paolo Rovatti, Alessandro Surace
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Patent number: 10434236Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: GrantFiled: May 23, 2016Date of Patent: October 8, 2019Assignee: Gambro Lundia ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Publication number: 20190275230Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: ApplicationFiled: October 26, 2017Publication date: September 12, 2019Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Patent number: 10265459Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.Type: GrantFiled: March 5, 2018Date of Patent: April 23, 2019Assignee: GAMBRO LUNDIA ABInventors: Francesco Fontanazzi, Alessandro Surace, Francesco Rosati
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Publication number: 20180193547Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.Type: ApplicationFiled: March 5, 2018Publication date: July 12, 2018Inventors: Francesco Fontanazzi, Alessandro Surace, Francesco Rosati
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Publication number: 20180169315Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: ApplicationFiled: May 23, 2016Publication date: June 21, 2018Inventors: Paolo ROVATTI, Alessandro SURACE, Cario Alberto LODI, Anders WALLENBORG, Anders NILLSON, Kristian SOLEM, Jan STERNBY, Thomas HERTZ
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Publication number: 20180140761Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: ApplicationFiled: May 23, 2016Publication date: May 24, 2018Inventors: Paolo Rovatti, Alessandro Surace, Cario Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Patent number: 9943636Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.Type: GrantFiled: October 28, 2013Date of Patent: April 17, 2018Assignee: GAMBRO LUNDIA ABInventors: Francesco Fontanazzi, Alessandro Surace, Francesco Rosati
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Patent number: 9925321Abstract: It is disclosed an apparatus for extracorporeal blood treatment (1) having a control unit (15) connected to an ultrafiltration device (20) and to a fluid preparation section (30) of fresh dialysis liquid. The control unit (15) is configured to receive measured values of the change of blood volume, the amount of ultrafiltration volume, and conductivity or to the concentration for at least one substance in the blood (BV %mes(t); UFmes(t), WLmes(t); Cbmes(t)); the control unit (15) is also configured to receive prescription values for the same parameters and to control ultrafiltration and adjust conductivity in the fresh dialysis liquid based on the difference between said measured values and said prescription values.Type: GrantFiled: December 16, 2013Date of Patent: March 27, 2018Assignee: Gambro Lundia ABInventors: Alessandro Surace, Paolo Rovatti
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Publication number: 20160303303Abstract: A method of operating an extracorporeal blood treatment includes, prior to commencing an extracorporeal blood treatment, reading from a storage device (4a, 5a) stored values of a patient-specific prescription parameter. These stored values relate to a sequence of previous extracorporeal blood treatments. In addition, the method includes processing the stored values of the parameter read from the storage device (4a, 5a) according to a predetermined algorithm to determine a current value of the patient-specific prescription parameter. The current value is then available for the subsequent extracorporeal blood treatment.Type: ApplicationFiled: December 10, 2014Publication date: October 20, 2016Applicant: Gambro Lundia ABInventors: Paolo ROVATTI, Alessandro SURACE
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Patent number: 9220830Abstract: An apparatus for extracorporeal blood treatment including a treatment unit; an extracorporeal blood circuit; an infusion line of a replacement fluid; a dialysis line connected in inlet to the second chamber; a fluid evacuation line; sensors for determining a first parameter relating to a patient's blood volume (BV %), a second parameter relating to an ultrafiltration flow rate (UFR) or to a patient's weight loss rate (WLR), a third parameter (Cd, Na) relating to a conductivity or concentration of a liquid crossing the dialysis line and/or the infusion line, and a fourth parameter relating to an infusion flow rate (QINF), and a control unit performing a control procedure to determine a variation in blood volume (BV %) and perform a setting sequence, wherein the control unit regulates a transmembrane pressure (TMP) to values which enable maximizing the convective exchanges.Type: GrantFiled: March 20, 2012Date of Patent: December 29, 2015Assignee: GAMBRO DASCO S.P.A.Inventors: Francesco Fontanazzi, Alessandro Surace, Francesco Paolini
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Publication number: 20150343129Abstract: It is disclosed an apparatus for extracorporeal blood treatment (1) having a control unit (15) connected to an ultrafiltration device (20) and to a fluid preparation section (30) of fresh dialysis liquid. The control unit (15) is configured to receive measured values of the change of blood volume, the amount of ultrafiltration volume, and conductivity or to the concentration for at least one substance in the blood (BV %mes(t); UFmes(t), WLmes(t); Cbmes(t)); the control unit (15) is also configured to receive prescription values for the same parameters and to control ultrafiltration and adjust conductivity in the fresh dialysis liquid based on the difference between said measured values and said prescription values.Type: ApplicationFiled: December 16, 2013Publication date: December 3, 2015Inventors: Alessandro Surace, Paolo Rovatti