Patents by Inventor Alessandro Tossi

Alessandro Tossi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial peptides
    Patent number: 7829524
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: November 9, 2010
    Assignee: Novozymes Adenium Biotech A/S
    Inventors: Dorotea Raventos Segura, Per Holse Mygind, Hans-Henrik Kristensen Hoegenhaug, Alessandro Tossi
  • Peptidomimetic inhibitors of retroviral proteases and their use as antivirals
    Patent number: 7691818
    Abstract: New peptidomimetic inhibitors of retroviral proteases are in particular for human immunodeficiency virus (HIV) protease. These inhibitors include as the core structure a new diamiriodiol isostere of the dipeptide Phe-Pro having four stereogenic centers. The inhibitors have been shown to inhibit HIV-protease and can therefore be usefully employed as antivirals for post-exposure prophylaxis and as a therapy for viral infections by a retrovirus, in particular HIV. The syntheses processes of the isosteres and inhibitors are also described.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: April 6, 2010
    Assignee: Universita' Degli Studi Di Treiste
    Inventors: Fabio Benedetti, Alessandro Tossi, Federico Berti, Pietro Campaner, Francesca Dinon
  • Antimicrobial Peptides
    Publication number: 20080213430
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: June 10, 2004
    Publication date: September 4, 2008
    Applicants: Novozymes A/S, Universita' Degli Studi Di Trieste Dipartimento di Biochimica
    Inventors: Dorotea Raventos Segura, Per Holse Mygind, Hans-Henrik Kristensen Hoegenhaug, Alessandro Tossi
  • Antimicrobial Peptides
    Publication number: 20070259087
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: June 10, 2004
    Publication date: November 8, 2007
    Applicant: Novozymes A/S
    Inventors: Dorotea Segura, Per Mygind, Alessandro Tossi, Hans-Henrik Hogenhaug
  • Peptidomimetic Inhibitors Of Retroviral Proteases And Their Use As Antivirals
    Publication number: 20070207968
    Abstract: The patent describes new peptidomimetic inhibitors of retroviral proteases, in particular of human immunodeficiency virus (HIV) protease. These inhibitors comprise as the core structure a new diaminodiol isostere of the dipeptide Phe-Pro having four stereogenic centres. The inhibitors of the invention have been shown to inhibit HIV protease and can therefore be usefully employed as antivirals for post-exposure prophylaxis and as a therapy for viral infections by a retrovirus, in particular HIV. The syntheses processes of the isosteres and inhibitors are also described.
    Type: Application
    Filed: June 15, 2005
    Publication date: September 6, 2007
    Applicant: UNIVERSITA' DEGLI STUDI DI TRIESTE
    Inventors: Fabio Benedetti, Alessandro Tossi, Federico Berti, Pietro Campaner, Francesca Dinon