Patents by Inventor Alessandro VACCHINI

Alessandro VACCHINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION
    Publication number: 20230099822
    Abstract: The invention relates to a method for modulating an interaction between an MR1 polypeptide and an MR1-specific T cell receptor molecule, whereby a MR1 polypeptide is contacted with a MR1 ligand compound that is a nucleobase adduct product reflecting a state of metabolic distress of a cell. The invention further relates to the use of compounds identified as MR1 ligands in vaccination or modulation of an MR1-restricted immune response.
    Type: Application
    Filed: January 18, 2021
    Publication date: March 30, 2023
    Applicant: UNIVERSITÄT BASEL
    Inventors: Gennaro DE LIBERO, Lucia MORI, Alessandro VACCHINI, Andrew CHANCELLOR, Julian SPAGNUOLO, Qinmei YANG