Patents by Inventor Alessia Rossi

Alessia Rossi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of daptomycin
    Patent number: 8313922
    Abstract: The present invention relates to an improved process for the production of Daptomycin by fermentation with Streptomyces roseosporus, in the presence of n-decanal or Cuphea oil as sources of the n-decanoyl side chain. These reagents allow to reduce toxicity effects on the bacteria and to avoid the use of solvents in the feeding solution.
    Type: Grant
    Filed: July 30, 2009
    Date of Patent: November 20, 2012
    Assignee: Antibioticos S.p.A.
    Inventors: Gianluca Bertetti, Antonella Malcangi, Roberto Muraca, Guido Trione, Alessia Rossi
  • Process for the preparation and purification of valgancyclovir hydrochloride
    Patent number: 7935818
    Abstract: A process for the preparation of valgancyclovir which comprises: a) reacting a compound of formula 7, in an aprotic solvent, in the presence of a condensing agent, with a compound of formula 8, wherein R1, and R2 may be, each independently, hydrogen, an halogen atom or an hydroxyl group; the double bond may either be in the E or Z configuration or a mixture thereof to yield a compound of formula 9 b) mild hydrolysis of compound obtained in a) to give valgancyclovir.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: May 3, 2011
    Assignee: Fidia Farmaceutici S.p.A.
    Inventors: Gianluca Belogi, Alessia Rossi, Angelo Bedeschi, Roberta Pizzocaro
  • PROCESS FOR THE PRODUCTION OF DAPTOMYCIN
    Publication number: 20100047873
    Abstract: The present invention relates to an improved process for the production of Daptomycin by fermentation with Streptomyces roseosporus, in the presence of n-decanal or Cuphea oil as sources of the n-decanoyl side chain. These reagents allow to reduce toxicity effects on the bacteria and to avoid the use of solvents in the feeding solution.
    Type: Application
    Filed: July 30, 2009
    Publication date: February 25, 2010
    Applicant: ANTIBIOTICOS S.p.A
    Inventors: Gianluca BERTETTI, Antonella Malcangi, Roberto Muraca, Guido Trione, Alessia Rossi
  • Process for the manufacture of famciclovir using phase-transfer catalysts
    Publication number: 20080154038
    Abstract: The invention relates to a process for the preparation of Famciclovir, which comprises the preparation of a compound of formula (II) wherein X is a halogen atom by reaction of a compound of formula (III) with a compound of formula (VII) wherein L is a leaving group, in the presence of a catalytic amount of a quaternary ammonium salt, followed by hydrogenation of compound (II) to Famciclovir.
    Type: Application
    Filed: April 11, 2007
    Publication date: June 26, 2008
    Inventors: Giorgio Chiodini, Alessia Rossi
  • Process for the preparation and purification of valgancyclovir
    Publication number: 20080076923
    Abstract: A process for the preparation of valgancyclovir which comprises: a) reacting a compound of formula 7, in an aprotic solvent, in the presence of a condensing agent, with a compound of formula 8, wherein R1, and R2 may be, each independently, hydrogen, an halogen atom or an hydroxyl group; the double bond may either be in the E or Z configuration or a mixture thereof to yield a compound of formula 9 b) mild hydrolysis of compound obtained in a) to give valgancyclovir.
    Type: Application
    Filed: June 20, 2007
    Publication date: March 27, 2008
    Inventors: Gianluca Belogi, Alessia Rossi, Angelo Bedeschi, Roberta Pizzocaro