Abstract: The invention relates to a method of improving a user's well-being in an interactive system, by: querying the user to determine a user identifier profile and the user's relative levels of a number of state-related traits, and identifying traits for which said relative levels deviate significantly from optimal; wherein the improvement includes: selecting, by a server, from a group of tested motivational messages which have been effective for other users to reduce the deviation in the levels of said traits, one or more selected motivational messages; where the amount of said deviation reduction is the average of all users reduction in deviation following receipt of said selected motivational messages; and sending the selected motivational messages to the device controlled by the user; and querying the user, by sending a questionnaire from the server to said device, to determine if said deviation is reduced.

Abstract: Disclosed is a system of education, monitoring and advising on glucose testing, diet, exercise and drug administration using a device which is carried by the patient and which is capable of: blood glucose testing, displaying messages advising the patient to initiate blood glucose testing, and of recording the results of the test; of displaying advice or further queries based on analysis of the results, and displaying messages relating to advice, education and/or further queries based on the analysis. The messages are optimized based on their effectiveness in bringing about a favorable response in the patient's blood glucose level, estimated HbA1c level, or based on other clinical endpoints.

Abstract: This business method includes: displaying one or more itineraries (including the shortest route, fastest route and most fuel-efficient route) for travel to both flexible and invariable appointments, updated in real time based on: user's location, destination changes and other factors, and wherein merchants within a defined proximity to the route can display information and offers to the user, and merchants pay the service which makes the itinerary selection services available and collects revenue from merchants for the right to make offers to the users, and determines the order of the merchant in a display to the user.