Patents by Inventor Alex Blyth

Alex Blyth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260258362
    Abstract: A method of preparing cells for therapeutic use is provided, in which a population of progenitor cells is cultured in cell culture conditions that promote differentiation of the progenitor cells comprising the presence of: G-CSF, GM-CSF, IL-3 and TNF; to produce a population of granulopoietic cells. The granulopoietic cells produced may be useful in methods of treatment, including the treatment of cancer and infections, and to modulate inflammatory cell responses.
    Type: Application
    Filed: March 8, 2024
    Publication date: September 3, 2026
    Applicant: LIFT BioSciences Ltd
    Inventors: Alex Blyth, Oxana POLYAKOVA, Aoife MCGINLEY, Samuel FLORENCE, Mihil PATEL, Durva PATEL, Andrew WILLIS
  • Publication number: 20260207663
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Application
    Filed: July 2, 2025
    Publication date: July 23, 2026
    Applicant: LIfT BioSciences Ltd
    Inventors: Alex Blyth, Nico Bruyniks
  • Publication number: 20250325584
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Application
    Filed: July 2, 2025
    Publication date: October 23, 2025
    Applicant: LIfT BioSciences Ltd
    Inventors: Alex Blyth, Nico Bruyniks
  • Patent number: 12370216
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Grant
    Filed: March 24, 2023
    Date of Patent: July 29, 2025
    Assignee: LIft BioSciences Ltd
    Inventors: Alex Blyth, Nico Bruyniks
  • Publication number: 20240285681
    Abstract: The invention relates to a granulocyte or stem cell (preferably granulocyte) for use in treating an infection. The invention also relates to said methods for identifying said granulocytes and stem cells capable of differentiating into said granulocytes, compositions and kits comprising the same, as well as uses of the same for treating an infection.
    Type: Application
    Filed: December 11, 2020
    Publication date: August 29, 2024
    Inventor: Alex Blyth
  • Patent number: 12070473
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein the haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to the granulocytes, methods for identifying the haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: August 27, 2024
    Assignee: LIFT BIOSCIENCES LTD
    Inventors: Alex Blyth, Nico Bruyniks
  • Publication number: 20240197776
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Application
    Filed: November 17, 2023
    Publication date: June 20, 2024
    Inventors: Alex Blyth, Nico Bruyniks
  • Patent number: 11878033
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: January 23, 2024
    Assignee: LIFT BIOSCIENCES LTD
    Inventors: Alex Blyth, Nico Bruyniks
  • Publication number: 20230346834
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Application
    Filed: March 24, 2023
    Publication date: November 2, 2023
    Applicant: LIfT BioSciences Ltd
    Inventors: Alex Blyth, Nico Bruyniks
  • Publication number: 20230203441
    Abstract: The invention relates to a method for determining the suitability of a granulocyte for treating cancer. The invention also relates to said granulocytes, methods for identifying said granulocytes and stem cells capable of differentiating into said granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 29, 2023
    Inventor: Alex Blyth
  • Patent number: 11642373
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: May 9, 2023
    Assignee: LIfT Biosciences Ltd
    Inventors: Alex Blyth, Nico Bruyniks
  • Publication number: 20210189340
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Application
    Filed: April 24, 2018
    Publication date: June 24, 2021
    Inventors: Alex Blyth, Nico Bruyniks
  • Publication number: 20190314409
    Abstract: The present invention relates to an in vitro culture of haematopoietic cells, wherein said haematopoietic cells differentiate to form granulocytes characterised by the ability to kill cancer cells. The invention also relates to said granulocytes, methods for identifying said haematopoietic cells and granulocytes, compositions and kits comprising the same, as well as uses of the same for treating cancer.
    Type: Application
    Filed: October 25, 2017
    Publication date: October 17, 2019
    Inventors: Alex Blyth, Nico Bruyniks