Patents by Inventor Alex E. MacKenzie

Alex E. MacKenzie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neuronal apoptosis inhibitor protein gene sequence and mutations causative of spinal muscular atrophy
    Patent number: 6429011
    Abstract: The gene for autosomal recessive neurodegenerative disorder Spinal Muscular Atrophy has been mapped to a region of chromosome 5. The gene encodes a protein having homology with apoptosis inhibitor proteins of viruses so that the encoded protein has been labelled as a neuronal apoptosis inhibitor protein (NAIP). A deletion in the (NAIP) domain was identified in persons with Type I, II and III Spinal Muscular Atrophy (SMA) and not in the normal non-SMA population.
    Type: Grant
    Filed: January 28, 2000
    Date of Patent: August 6, 2002
    Assignees: University of Ottawa, Research Development Corporation of Japan
    Inventors: Alex E. MacKenzie, Robert G. Korneluk, Natalie Roy, Mani S. Mahadevan, Michael McLean, Joh-E Ikeda
  • Neuronal apoptosis inhibitor protein, gene sequence and mutations causative of spinal muscular atrophy
    Patent number: 6020127
    Abstract: The gene for the autosomal recessive neurodegenerative disorder Spinal Muscular Atrophy has been mapped to a region of chromosome 5. The gene encodes a protein having homology with apoptosis inhibitor proteins of viruses so that the encoded protein has been labelled as a neuronal apoptosis inhibitor protein (NAIP). A deletion in the (NAIP) domain was identified in persons with Type I, II and III Spinal Muscular Atrophy (SMA) and not in the normal non-SMA population.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: February 1, 2000
    Assignees: The University of Ottawa, Research Development Corp. of Japan
    Inventors: Alex E. MacKenzie, Robert G. Korneluk, Natalie Roy, Mani S. Mahadevan, Michael McLean, Joh-E Ikeda