Patents by Inventor Alex Herman Copmans

Alex Herman Copmans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE
    Publication number: 20090012108
    Abstract: The present invention relates to a pharmaceutical composition comprising as active ingredient the hydrochloric acid salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethyl-phenyl]amino]-2-pyrimidinyl]amino]benzonitrile and to processes for their preparation.
    Type: Application
    Filed: July 7, 2008
    Publication date: January 8, 2009
    Inventors: Jerome Emile Guillemont, Paul Theodoor Agnes Stevens, Alex Herman Copmans, Jozef Peeters, Alfred Elisabeth Stappers, Roger Petrus Gerebern Vandecruys, Paul Stoffels
  • Process for preparing enantiomerically pure 6-{4-chlorophenyl) (1 H-1,2,4-triazol-1-YL) methyl}-1-methyl-1 H-benzotriazole
    Patent number: 5746840
    Abstract: A process for preparing (+)-6-?(4-chlorophenyl)(1H- 1,2,4-triazol-1-yl)methyl!-1-methyl-1H-benzotriazole comprising the resolution of (.+-.)-6-!(4-chlorophenyl)-hydrazinomethyl)-1-methyl-1H-benzotriazole and converting the appropriate enantiomerically pure hydrazine intermediate into (+)-6-?(4-chlorophenyl)(H- 1,2,4-triazol-1-yl)methyl!-1-methyl-1H-benzotriazole.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: May 5, 1998
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Albert Louis Anna Willemsens, Walter Louis Antoine Verstappen, Alex Herman Copmans, Anna Maria Jozefa Vandendriessche, Alfons Gaston Maria De Knaep, Marc Gaston Venet
  • Process for preparing enantiomerically pure 6-[(4-chlorophenyl) (1H-1,2,4-triazol-1-yl) methyl]-1-methyl-1H-benzotrizole
    Patent number: 5663354
    Abstract: A process for preparing (+)-6-[(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H-benzotri azole comprising the resolution of (.+-.)-6-[(4-chlorophenyl)-hydrazinomethyl)-1-methyl-1H-benzotriazole and converting the appropriate enantiomerically pure hydrazine intermediate into (+)-6-[(4-chlorophenyl)(1 H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H-benzotriazole.
    Type: Grant
    Filed: April 18, 1995
    Date of Patent: September 2, 1997
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Albert Louis Anna Willemsens, Walter Louis Antoine Verstappen, Alex Herman Copmans, Anna Maria Jozefa Vandendriessche, Alfons Gaston Maria De Knaep, Marc Gaston Venet