Patents by Inventor Alex J. Proescher

Alex J. Proescher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9377438
    Abstract: A kit for separating and concentrating nucleic acid and protein targets includes labeled reagents which affect simultaneous co-purification and concentration of a nucleic acid and a protein, a gel isotachophoresis separation unit to which a sample comprising the nucleic acid and the protein is added, a detection unit for the detection of the presence of the nucleic acid and the protein, and instructions for use. The gel electrophoresis includes a gel box having a negative electrode side and a positive electrode side, the negative electrode side being filled with a first buffer comprising 2-Hydroxy-N-(tris(hydroxymethyl)methyl)-3-aminopropanesulfonic acid buffer and the positive electrode side being filled with a second buffer being different than the first buffer. The gel isotachophoresis separation is configured to subject the sample to isotachophoresis using a voltage.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: June 28, 2016
    Assignee: The Johns Hokpins University
    Inventors: Charles C. Young, Alex J. Proescher, Emily E. Smith
  • Publication number: 20140332389
    Abstract: A kit for separating and concentrating nucleic acid and protein targets includes labeled reagents which affect simultaneous co-purification and concentration of a nucleic acid and a protein, a gel isotachophoresis separation unit to which a sample comprising the nucleic acid and the protein is added, a detection unit for the detection of the presence of the nucleic acid and the protein, and instructions for use. The gel electrophoresis includes a gel box having a negative electrode side and a positive electrode side, the negative electrode side being filled with a first buffer comprising 2-Hydroxy-N-(tris(hydroxymethyl)methyl)-3-aminopropanesulfonic acid buffer and the positive electrode side being filled with a second buffer being different than the first buffer. The gel isotachophoresis separation is configured to subject the sample to isotachophoresis using a voltage.
    Type: Application
    Filed: July 30, 2014
    Publication date: November 13, 2014
    Inventors: Charles C. Young, Alex J. Proescher, Emily E. Smith
  • Patent number: 8865401
    Abstract: A method of simultaneously co-purifying and concentrating nucleic acid and protein targets is described. The method includes automation of the entire sample preparation process, performed by having an analyst add a sample into a device that performs all of the steps necessary to prepare a sample for analysis. The method provides for samples that are not split during the sample preparation process and where common purification methods can be used for purifying multiple analytes.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: October 21, 2014
    Assignee: The Johns Hopkins University
    Inventors: Charles C. Young, Alex J. Proescher, Emily E. Smith
  • Publication number: 20100323913
    Abstract: A method of simultaneously co-purifying and concentrating nucleic acid and protein targets is described. The method includes automation of the entire sample preparation process, performed by having an analyst add a sample into a device that performs all of the steps necessary to prepare a sample for analysis. The method provides for samples that are not split during the sample preparation process and where common purification methods can be used for purifying multiple analytes.
    Type: Application
    Filed: June 17, 2010
    Publication date: December 23, 2010
    Inventors: Charles C. Young, Alex J. Proescher, Emily E. Smith