Abstract: The invention relates to a device for closing an atrial appendage, particularly the left atrial appendage, comprising a closing element, designed to be arranged in an atrial appendage entrance and to prevent an entrance of blood into the atrial appendage and/or a leakage of thrombus out of the atrial appendage, which is configured that it does not, in the implanted state, protrude out of the atrial appendage into the atrium of the heart; a first anchoring element, which is arranged adjacent to the closing element and connected to the closing element, wherein the first anchoring element is designed for an anchoring on an atrial appendage tissue wall, a connecting element which is at least in a radial direction flexible and connected to the first anchoring element and a second anchoring element, which is connected to the connecting element and designed for an anchoring on an atrial appendage tissue wall.

Abstract: A left atrial appendage occlusion device includes a deformable wire having a proximal portion and a distal portion, wherein the deformable wire is configured to form a first predetermined expanded shape and a second predetermined relaxed shape; a distal anchor that includes a plurality of hooks or barbs extending from a point at an overall distal end of the deformable wire, the distal anchor being configured to attach the device to an interior wall of the left atrial appendage; and a sheet attached to the proximal portion of the deformable wire.

Abstract: The invention relates to a device for closing an atrial appendage, particularly the left atrial appendage, comprising a closing element, designed to be arranged in an atrial appendage entrance and to prevent an entrance of blood into the atrial appendage and/or a leakage of thrombus out of the atrial appendage, which is configured that it does not, in the implanted state, protrude out of the atrial appendage into the atrium of the heart; a first anchoring element, which is arranged adjacent to the closing element and connected to the closing element, wherein the first anchoring element is designed for an anchoring on an atrial appendage tissue wall, a connecting element which is at least in a radial direction flexible and connected to the first anchoring element and a second anchoring element, which is connected to the connecting element and designed for an anchoring on an atrial appendage tissue wall.

Abstract: A left atrial appendage occlusion device including an occluder disk configured to substantially prevent blood from at least one of entering and exiting the left atrial appendage, a middle portion including a coiled element and a first anchoring element. The coiled element connects to the occluder disk, has a substantially constant cross section and allows for variable length, variable orientation, and/or varied angles. The first anchoring element connects to the coiled element and includes scalloped edges that are configured to anchor the occlusion device to inner walls of the left atrial appendage and reduce the risk of one of penetration and perforation of walls of the left atrial appendage. The left atrial appendage occlusion device may also include a self-centering element that connects to the occluder disk and middle portion and is configured to center the occlusion device within the orifice of the left atrial appendage.

Abstract: A left atrial appendage occlusion device including an occluder disk configured to substantially prevent blood from at least one of entering and exiting the left atrial appendage, a middle portion including a coiled element and a first anchoring element. The coiled element connects to the occluder disk, has a substantially constant cross section and allows for variable length, variable orientation, and/or varied angles. The first anchoring element connects to the coiled element and includes scalloped edges that are configured to anchor the occlusion device to inner walls of the left atrial appendage and reduce the risk of one of penetration and perforation of walls of the left atrial appendage. The left atrial appendage occlusion device may also include a self-centering element that connects to the occluder disk and middle portion and is configured to center the occlusion device within the orifice of the left atrial appendage.

Abstract: The present invention provides devices and methods for occluding the left atrial appendage. The device includes an easily deployed wire structure of shape memory material sized to be appropriate for use in a patient. The device may be manufactured in various sizes for use in various patients. The device has a sheet of material attached for eclipsing the opening of the left atrial appendage and means for secured attachment substantially within the left atrial appendage. The method includes deploying the device within the left atrial appendage, securely anchoring the device, and ensuring that a sheet of material eclipses the opening of the left atrial appendage. These features are incorporated into the improved devices and methods in order to more effectively aid in the prevention of clot formation and clot migration into or out of the left atrial appendage to greatly decrease the risk of stroke in patients with atrial fibrillation.