Abstract: A method for treatment of peripheral arterial disease conditions comprising systemically administering an effective amount of therapeutic stem cells. Included within the scope of the invention is intravenous administration of a therapeutic amount of ischemic tolerant mesenchymal stem cells in the treatment of peripheral arterial disease.

Abstract: The invention relates to transgenic stem cells for therapeutic use. Stem cells according to the invention comprise at least one therapeutic trans gene that is expressed when transplanted to a subject. Methods of use and manufacturing the transgenic stem cells of the invention are also contemplated, including the use of transiently transgenic G-CSF bone marrow stem cells for treating the penumbra of ischemic tissues such as central nervous system tissues.

Abstract: The invention relates to transgenic stem cells for therapeutic use. Stem cells according to the invention comprise at least one therapeutic trans gene that is expressed when transplanted to a subject. Methods of use and manufacturing the transgenic stem cells of the invention are also contemplated, including the use of transiently transgenic G-CSF bone marrow stem cells for treating the penumbra of ischemic tissues such as central nervous system tissues.

Abstract: The invention provides, in part, novel SV-BR cancer cell lines. The invention provides a novel cell line SV-BR-1 deposited under ATCC PTA-1712 and SV-BR-1-GM cells deposited under ATCC PTA-1713. The invention further relates to therapeutic and non-therapeutic uses of the novel cell lines. Therapeutic uses include the use of SV-BR cell lines as cancer vaccines, and in particular, or the treatment of cancer.

Abstract: Compounding or extrusion rates can be increased by splitting the polymer solid feed. Melting of additional solid polymer is significantly assisted by excess enthalpy from incoming melt from a primary mixing stage. Depending on resin rheology and melting characteristics, rate increases were achieved of from up to about 55 to about 100% rate increase over the use of a single feed at the same rotor speed. The net result is a decrease in the overall SEI (specific energy input to the polymer) and thus melt temperatures.

Abstract: The invention provides, in part, novel SV-BR cancer cell lines. The invention provides a novel cell line SV-BR-1 deposited under ATCC ______, and SV-BR-1-GM cells deposited under ATCC ______. The invention further relates to therapeutic and non-therapeutic uses of the novel cell lines. Therapeutic uses include the use of SV-BR cell lines as cancer vaccines, and in particular, or the treatment of cancer.

Abstract: A process for the preparation of a composition useful in telecommunications jacketing comprising: (i) introducing a polyolefin into the first mixing zone of a melt/mixer having first and second mixing zones; (ii) introducing particulate carbon black per se or a premix of said carbon black and polyolefin into the first mixing zone, said carbon black being in an amount of about 2 to about 50 percent based on the weight of the polyolefin introduced into the first mixing zone; (iii) melting the polyolefin in the presence of the carbon black in the first mixing zone; (iv) mixing the carbon black and the molten polyolefin in the first mixing zone to provide a molten mixture; (v) passing the molten mixture from step (iv) into the second mixing zone; (vi) adding sufficient polyolefin to the molten mixture from step (v) to dilute the carbon black to a level of about 2 to about 3 percent by weight based on the weight of the total polyolefin in the melt/mixer; (vii) mixing the added polyolefin with the molten mix

Abstract: A process for the preparation of a semiconducting shield composition comprising: (i) introducing an elastomer into a melt/mixer having a melting zone and a mixing zone; (ii) introducing particulate conductive carbon black into the melt/mixer in an amount of about 10 to about 25 percent by weight based on the weight of the resin; (iii) melting the elastomer in the melting zone; (iv) mixing the carbon black and the molten elastomer in the mixing zone; (v) optionally, pelletizing the mixture of carbon black and elastomer; (vi) recycling the mixture of carbon black and elastomer from step (iv) or the pellets from step (v) to a melt/mixer; (vii) introducing additional particulate semiconductive carbon black into the melt/mixer in an amount sufficient to provide a total amount of carbon black in the range of about 25 to about 50 percent by weight based on the weight of the resin; (viii) melting and mixing the mixture from step (vii); and (ix) pelletizing or extruding the mixture from step (viii).

Abstract: Disclosed is a process for pelletizing high melt flow crystalline polymers to produce crystalline pellet products. The process includes feeding a polyolefin granular or pelleted polymer into a melting/mixing mechanism to provide a molten polymer material. The molten polymer material is optionally passed through a melt pump and through a die to form a plurality of molten polymer strands. The plurality of molten polymer strands then are passed through or along a water trough declined with respect to the direction of the horizontal arrays where they are sprayed with cool liquid a plurality of times in such a manner that the sprayed cool liquid creates turbulent flow and disturbs a thin film of hot water and/or steam that forms around each molten polymer strand as it is cooled without undesirable axial acceleration of the polymer strands. Subjecting the molten polymer strands to such a cooling procedure produces cooled polymer strands, which then are fed to a cutting mechanism and cut into pellets.

Abstract: Disclosed is a process making polyolefin pellet products that contain at least one unreacted free radical generator which, when heated, undergo chemical degradation producing a low viscosity polymer. The process includes contacting the polyolefin pellet with the at least one free radical generator to coat the pellet, and contacting the coated pellets and at least one unreacted free radical generator at an elevated temperature and for a period of time sufficient for the free radical initiator to soak into the interior of the pellets. The process of the invention enables the production of polyolefin pellets having any desired amount of free radical generator and therefore, production of a desired viscosity, and improves the processability of the polyolefin pellet at customer fabrication facilities to thereby provide superior quality final articles.

Abstract: A process comprising the following steps: (a) maintaining the process in an essentially oxygen-free state; (b) introducing a first polymer directly from the polymerization reactor in which it was prepared, in molten form, into a mixer/compounder; (c) reducing any higher pressure accompanying the first polymer from the polymerization reactor to the mixer/compounder to a pressure in the range of about 0 to about 5 barg; (d) adding additives selected from the group consisting of antioxidants, second polymers, other polymer enhancing additives, and mixtures thereof to the mixer/compounder, and mixing same with the molten first polymer; (e) passing the molten mixture from step (d) through one or more screens, each having a maximum opening size of about 25 microns; (f) pelletizing the mixture from step (e); (g) introducing the pellets into a spraying chamber, the interior of said chamber being operated in a static condition; (h) spraying the pellets in the chamber with a crosslinking formulation including an organi