Patents by Inventor Alex LEPAK

Alex LEPAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hemoglobin-based oxygen carrier compositions
    Patent number: 12698320
    Abstract: Provided herein are modified hemoglobin (Hb) comprising at least two subunits of a Hb intramolecularly crosslinked with a compound of formula (I), or salt, stereoisomer, or deuterated form thereof, wherein X, R1, and R2 are defined herein. The modified Hb can further comprise residues functionalized with reactive groups. Also provided herein are multimerized hemoglobin (Hb) compositions comprising a reaction product of: the modified Hb comprising a residue functionalized with one or more first reactive groups for click reaction and a reactant molecule comprising second reactive groups complementary to the first reactive group for the click reaction.
    Type: Grant
    Filed: May 15, 2025
    Date of Patent: August 4, 2026
    Assignee: 20BLOC, INC.
    Inventors: Alex Lepak, David Rozzell, Sky Ferrara, Kai Lu, Martin Michael Dcona, Nitin Pawar, Erik Goebel
  • HEMOGLOBIN-BASED OXYGEN CARRIER COMPOSITIONS
    Publication number: 20250353897
    Abstract: Provided herein are modified hemoglobin (Hb) comprising at least two subunits of a Hb intramolecularly crosslinked with a compound of formula (I), or salt, stereoisomer, or deuterated form thereof, wherein X, R1, and R2 are defined herein. The modified Hb can further comprise residues functionalized with reactive groups. Also provided herein are multimerized hemoglobin (Hb) compositions comprising a reaction product of: the modified Hb comprising a residue functionalized with one or more first reactive groups for click reaction and a reactant molecule comprising second reactive groups complementary to the first reactive group for the click reaction.
    Type: Application
    Filed: May 15, 2025
    Publication date: November 20, 2025
    Inventors: Alex LEPAK, David ROZZELL, Sky FERRARA, Kai LU, Martin Michael DCONA, Nitin PAWAR, Erik GOEBEL