Patents by Inventor Alex Nanna

Alex Nanna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dual variable domain immunoconjugates and uses thereof
    Patent number: 11197934
    Abstract: Dual variable domain (DVD) immunoconjugates and uses thereof are provided. Aspects of the subject immunoconjugates include a DVD immunoglobulin molecule having a first and a second variable domain, and a cargo moiety (e.g., a drug moiety) that is covalently conjugated to the second variable domain via a linker. Methods of making and using the subject immunoconjugates in the prevention and/or treatment of cancer and other diseases are also provided.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: December 14, 2021
    Assignee: The Scripps Research Institute
    Inventors: Christoph Rader, Alex Nanna, William Roush
  • DUAL VARIABLE DOMAIN IMMUNOCONJUGATES AND USES THEREOF
    Publication number: 20180250415
    Abstract: Dual variable domain (DVD) immunoconjugates and uses thereof are provided. Aspects of the subject immunoconjugates include a DVD immunoglobulin molecule having a first and a second variable domain, and a cargo moiety (e.g., a drug moiety) that is covalently conjugated to the second variable domain via a linker. Methods of making and using the subject immunoconjugates in the prevention and/or treatment of cancer and other diseases are also provided.
    Type: Application
    Filed: September 16, 2016
    Publication date: September 6, 2018
    Inventors: Christoph Rader, Alex Nanna, William Roush