Patents by Inventor Alex Ng
Alex Ng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20250150105Abstract: A method includes: at a processor of a computing device having a first communications interface and a second communications interface, controlling the first communications interface to transmit data; at the processor, determining that the second communications interface is active concurrently with data transmission by the first communications interface; obtaining, at the processor, a performance metric corresponding to the second communications interface; in response to determining that the performance metric is below a threshold, selecting a mitigation action at the processor; and controlling the first communications interface according to the selected mitigation action.Type: ApplicationFiled: November 2, 2023Publication date: May 8, 2025Inventors: Harish Arora, Chu Pang Alex Ng, Jiallang Tan, Benjamin Jean Limongi, Jingyang Hu
-
Patent number: 12195756Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.Type: GrantFiled: February 9, 2024Date of Patent: January 14, 2025Assignee: President and Fellows of Harvard CollegeInventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
-
Publication number: 20240309318Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.Type: ApplicationFiled: May 23, 2024Publication date: September 19, 2024Applicant: President and Fellows of Harvard CollegeInventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
-
Publication number: 20240254437Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.Type: ApplicationFiled: February 9, 2024Publication date: August 1, 2024Applicant: President and Fellows of Harvard CollegeInventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
-
Patent number: 12031153Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.Type: GrantFiled: November 30, 2018Date of Patent: July 9, 2024Assignee: President and Fellows of Harvard CollegeInventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
-
Publication number: 20240209435Abstract: Provided herein, in some embodiments, are methods and compositions for identifying combinations of transcription factors, for example, those involved in cell type conversion processes, such as cell differentiation.Type: ApplicationFiled: September 6, 2023Publication date: June 27, 2024Applicant: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, George M. Church, Parastoo Khoshakhlagh
-
Publication number: 20240209321Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversions between cell identities; however, the extent to which TFs can alter cell identity has not been systematically assessed. Here, we assembled a human TFome, a comprehensive expression library of 1,578 human TF clones with full coverage of the major TF families. By systematically screening the human TFome, we identified 77 individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression profiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.Type: ApplicationFiled: October 27, 2023Publication date: June 27, 2024Applicant: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
-
Publication number: 20240117312Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversion between cell identities; however, the extent to which TFs can alter cell identity has not been systematic ally assessed. Here, we assembled a “human TFome,” a comprehensive expression library of 1,578 human TF clones with fall coverage of the major TF families. By systematically screening the human TFome, we identified many individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression pantiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.Type: ApplicationFiled: May 18, 2023Publication date: April 11, 2024Applicant: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
-
Publication number: 20240106061Abstract: Battery pack transmissions are disclosed herein. An example battery pack including at least one battery cell; a radio frequency (RF) chip; a battery contact contacting an end of the at least one battery cell; a first excitor connecting to the battery contact via the first RF port; and a second excitor connecting to the battery contact via the second RF port; wherein: the RF chip determining if the signal is to be transmitted at a first frequency or a second frequency, the RF chip sends the signal to the battery contact via the first excitor, the first excitor resonates at a first transmission frequency and energizes the at least one battery cell and the battery contact at the first frequency for transmission of the signal, and when the signal is transmitting at the second frequency, the RF chip sends the signal to the battery contact via the second excitor.Type: ApplicationFiled: September 26, 2022Publication date: March 28, 2024Inventors: Chu Pang Alex Ng, Colin Graham
-
Patent number: 11845960Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversions between cell identities; however, the extent to which TFs can alter cell identity has not been systematically assessed. Here, we assembled a human TFome, a comprehensive expression library of 1,578 human TF clones with full coverage of the major TF families. By systematically screening the human TFome, we identified 77 individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression profiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.Type: GrantFiled: September 12, 2017Date of Patent: December 19, 2023Assignee: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
-
Patent number: 11788131Abstract: Provided herein, in some embodiments, are methods and compositions for identifying combinations of transcription factors, for example, those involved in cell type conversion processes, such as cell differentiation.Type: GrantFiled: April 5, 2019Date of Patent: October 17, 2023Assignee: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, George M. Church, Parastoo Khoshakhlagh
-
Publication number: 20220204926Abstract: Provided herein is a differentiation agent that consist essentially of SOX9 for the production of oligodendrocyte progenitor cells (OPCs) from pluripotent stem cells (PSCs). Also provided herein are methods of producing the PSCs and methods of using the PSCs to produce OPCs and oligodendrocytes.Type: ApplicationFiled: November 29, 2021Publication date: June 30, 2022Applicant: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, Parastoo Khoshakhlagh, George M. Church
-
Publication number: 20220019800Abstract: A method in a mobile computing device includes: obtaining order collection data containing (i) item identifiers corresponding to a set of target items and a set of non-target items, (ii) a reference layout indicating, within a region of a facility, respective positions of the target items and the non-target items, and (iii) item recognition data for the target items and the non-target items; controlling an image sensor of the mobile computing device to acquire an image of a portion of the region; based on the item recognition data, detecting an item from the image; when the detected item is a target item, controlling an output assembly of the mobile computing device to present a prompt to collect the detected item; and when the detected item is a non-target item, controlling the output assembly to present a directional guide towards a selected target item based on the reference layout.Type: ApplicationFiled: July 17, 2020Publication date: January 20, 2022Inventors: Chu Pang Alex Ng, Yi-Hsuan Yeh
-
Publication number: 20210171902Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.Type: ApplicationFiled: November 30, 2018Publication date: June 10, 2021Applicant: President and Fellows of Harvard CollegeInventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
-
Publication number: 20210054448Abstract: Provided herein, in some embodiments, are methods and compositions for identifying combinations of transcription factors, for example, those involved in cell type conversion processes, such as cell differentiation.Type: ApplicationFiled: April 5, 2019Publication date: February 25, 2021Applicant: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, George M. Church, Parastoo Khoshakhlagh
-
Publication number: 20200063105Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversions between cell identities; however, the extent to which TFs can alter cell identity has not been systematically assessed. Here, we assembled a “human TFome,” a comprehensive expression library of 1,578 human TF clones with full coverage of the major TF families. By systematically screening the human TFome, we identified many individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression profiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.Type: ApplicationFiled: April 30, 2018Publication date: February 27, 2020Applicant: President and Fellows of Harvard CollegeInventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
-
Patent number: 9446322Abstract: A toy horse having a horse body, wherein the horse body includes a saddle board, two side boards, each side board being provided with a straight horse-back panel on its top, the two side boards being arranged opposite to each other symmetrically, which makes the horse-back panel of the two side boards being coplanar, the two side boards being removably installed on the saddle board, which makes the horse-back panel of the two side boards being abutted against the bottom of the saddle board, and the bottom of two side boards being shaped curly. The toy horse allows for portability of carry, convenience of assemble and comfortableness of ride.Type: GrantFiled: January 2, 2015Date of Patent: September 20, 2016Assignee: SCIENTIFIC PU FOAM CO., LIMITEDInventors: Ping Fun Alex Ng, Kin Wai Ho
-
Publication number: 20160248972Abstract: A surveillance camera, useful for capturing the movement of an animate object across a wide field of view, includes three separate lens apertures having fixed and adjacent fields of view. Each lens aperture has an associated image sensor that captures the field of view for combination by a microprocessor unit to yield a panoramic image.Type: ApplicationFiled: February 23, 2015Publication date: August 25, 2016Applicant: EBSCO INDUSTRIES, INCInventors: Jeff Garrison, Bart Stephens, Alex Ng, Patrick Cheung
-
Patent number: 9160347Abstract: A method and apparatus for operating an electronic device is provided. The electronic device, which includes a phase lock loop (PLL) receives sensor indicators from at least one sensor. Upon receiving sensor indicators, the device identifies a motion indicator based on the sensor indicators. A parameter of the PLL is adjusted based on the motion indicator, the PLL having at least one component susceptible to microphonics. When the PLL includes a charge pump, a parameter that may be adjusted is a pump current of the charge pump. When the PLL further comprises an oscillator for generating a reference signal, the parameter that may be adjusted is a trim of the oscillator.Type: GrantFiled: August 7, 2014Date of Patent: October 13, 2015Assignee: Symbol Technologies, LLCInventors: Irfan Kadri, Chu Pang Alex Ng
-
Publication number: 20150182866Abstract: A toy horse having a horse body, wherein the horse body includes a saddle board, two side boards, each side board being provided with a straight horse-back panel on its top, the two side boards being arranged opposite to each other symmetrically, which makes the horse-back panel of the two side boards being coplanar, the two side boards being removably installed on the saddle board, which makes the horse-back panel of the two side boards being abutted against the bottom of the saddle board, and the bottom of two side boards being shaped curly. The toy horse allows for portability of carry, convenience of assemble and comfortableness of ride.Type: ApplicationFiled: January 2, 2015Publication date: July 2, 2015Inventors: Ping Fun Alex NG, KIN WAI HO