Patents by Inventor Alex Ng

Alex Ng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250150105
    Abstract: A method includes: at a processor of a computing device having a first communications interface and a second communications interface, controlling the first communications interface to transmit data; at the processor, determining that the second communications interface is active concurrently with data transmission by the first communications interface; obtaining, at the processor, a performance metric corresponding to the second communications interface; in response to determining that the performance metric is below a threshold, selecting a mitigation action at the processor; and controlling the first communications interface according to the selected mitigation action.
    Type: Application
    Filed: November 2, 2023
    Publication date: May 8, 2025
    Inventors: Harish Arora, Chu Pang Alex Ng, Jiallang Tan, Benjamin Jean Limongi, Jingyang Hu
  • Patent number: 12195756
    Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.
    Type: Grant
    Filed: February 9, 2024
    Date of Patent: January 14, 2025
    Assignee: President and Fellows of Harvard College
    Inventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
  • Publication number: 20240309318
    Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.
    Type: Application
    Filed: May 23, 2024
    Publication date: September 19, 2024
    Applicant: President and Fellows of Harvard College
    Inventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
  • Publication number: 20240254437
    Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.
    Type: Application
    Filed: February 9, 2024
    Publication date: August 1, 2024
    Applicant: President and Fellows of Harvard College
    Inventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
  • Patent number: 12031153
    Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: July 9, 2024
    Assignee: President and Fellows of Harvard College
    Inventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
  • Publication number: 20240209435
    Abstract: Provided herein, in some embodiments, are methods and compositions for identifying combinations of transcription factors, for example, those involved in cell type conversion processes, such as cell differentiation.
    Type: Application
    Filed: September 6, 2023
    Publication date: June 27, 2024
    Applicant: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, George M. Church, Parastoo Khoshakhlagh
  • Publication number: 20240209321
    Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversions between cell identities; however, the extent to which TFs can alter cell identity has not been systematically assessed. Here, we assembled a human TFome, a comprehensive expression library of 1,578 human TF clones with full coverage of the major TF families. By systematically screening the human TFome, we identified 77 individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression profiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.
    Type: Application
    Filed: October 27, 2023
    Publication date: June 27, 2024
    Applicant: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
  • Publication number: 20240117312
    Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversion between cell identities; however, the extent to which TFs can alter cell identity has not been systematic ally assessed. Here, we assembled a “human TFome,” a comprehensive expression library of 1,578 human TF clones with fall coverage of the major TF families. By systematically screening the human TFome, we identified many individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression pantiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.
    Type: Application
    Filed: May 18, 2023
    Publication date: April 11, 2024
    Applicant: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
  • Publication number: 20240106061
    Abstract: Battery pack transmissions are disclosed herein. An example battery pack including at least one battery cell; a radio frequency (RF) chip; a battery contact contacting an end of the at least one battery cell; a first excitor connecting to the battery contact via the first RF port; and a second excitor connecting to the battery contact via the second RF port; wherein: the RF chip determining if the signal is to be transmitted at a first frequency or a second frequency, the RF chip sends the signal to the battery contact via the first excitor, the first excitor resonates at a first transmission frequency and energizes the at least one battery cell and the battery contact at the first frequency for transmission of the signal, and when the signal is transmitting at the second frequency, the RF chip sends the signal to the battery contact via the second excitor.
    Type: Application
    Filed: September 26, 2022
    Publication date: March 28, 2024
    Inventors: Chu Pang Alex Ng, Colin Graham
  • Patent number: 11845960
    Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversions between cell identities; however, the extent to which TFs can alter cell identity has not been systematically assessed. Here, we assembled a human TFome, a comprehensive expression library of 1,578 human TF clones with full coverage of the major TF families. By systematically screening the human TFome, we identified 77 individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression profiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: December 19, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
  • Patent number: 11788131
    Abstract: Provided herein, in some embodiments, are methods and compositions for identifying combinations of transcription factors, for example, those involved in cell type conversion processes, such as cell differentiation.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: October 17, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, George M. Church, Parastoo Khoshakhlagh
  • Publication number: 20220204926
    Abstract: Provided herein is a differentiation agent that consist essentially of SOX9 for the production of oligodendrocyte progenitor cells (OPCs) from pluripotent stem cells (PSCs). Also provided herein are methods of producing the PSCs and methods of using the PSCs to produce OPCs and oligodendrocytes.
    Type: Application
    Filed: November 29, 2021
    Publication date: June 30, 2022
    Applicant: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, Parastoo Khoshakhlagh, George M. Church
  • Publication number: 20220019800
    Abstract: A method in a mobile computing device includes: obtaining order collection data containing (i) item identifiers corresponding to a set of target items and a set of non-target items, (ii) a reference layout indicating, within a region of a facility, respective positions of the target items and the non-target items, and (iii) item recognition data for the target items and the non-target items; controlling an image sensor of the mobile computing device to acquire an image of a portion of the region; based on the item recognition data, detecting an item from the image; when the detected item is a target item, controlling an output assembly of the mobile computing device to present a prompt to collect the detected item; and when the detected item is a non-target item, controlling the output assembly to present a directional guide towards a selected target item based on the reference layout.
    Type: Application
    Filed: July 17, 2020
    Publication date: January 20, 2022
    Inventors: Chu Pang Alex Ng, Yi-Hsuan Yeh
  • Publication number: 20210171902
    Abstract: Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes.
    Type: Application
    Filed: November 30, 2018
    Publication date: June 10, 2021
    Applicant: President and Fellows of Harvard College
    Inventors: Parastoo Khoshakhlagh, Hon Man Alex Ng, George M. Church
  • Publication number: 20210054448
    Abstract: Provided herein, in some embodiments, are methods and compositions for identifying combinations of transcription factors, for example, those involved in cell type conversion processes, such as cell differentiation.
    Type: Application
    Filed: April 5, 2019
    Publication date: February 25, 2021
    Applicant: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, George M. Church, Parastoo Khoshakhlagh
  • Publication number: 20200063105
    Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversions between cell identities; however, the extent to which TFs can alter cell identity has not been systematically assessed. Here, we assembled a “human TFome,” a comprehensive expression library of 1,578 human TF clones with full coverage of the major TF families. By systematically screening the human TFome, we identified many individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression profiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.
    Type: Application
    Filed: April 30, 2018
    Publication date: February 27, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Hon Man Alex Ng, George M. Church, Volker Busskamp
  • Patent number: 9446322
    Abstract: A toy horse having a horse body, wherein the horse body includes a saddle board, two side boards, each side board being provided with a straight horse-back panel on its top, the two side boards being arranged opposite to each other symmetrically, which makes the horse-back panel of the two side boards being coplanar, the two side boards being removably installed on the saddle board, which makes the horse-back panel of the two side boards being abutted against the bottom of the saddle board, and the bottom of two side boards being shaped curly. The toy horse allows for portability of carry, convenience of assemble and comfortableness of ride.
    Type: Grant
    Filed: January 2, 2015
    Date of Patent: September 20, 2016
    Assignee: SCIENTIFIC PU FOAM CO., LIMITED
    Inventors: Ping Fun Alex Ng, Kin Wai Ho
  • Publication number: 20160248972
    Abstract: A surveillance camera, useful for capturing the movement of an animate object across a wide field of view, includes three separate lens apertures having fixed and adjacent fields of view. Each lens aperture has an associated image sensor that captures the field of view for combination by a microprocessor unit to yield a panoramic image.
    Type: Application
    Filed: February 23, 2015
    Publication date: August 25, 2016
    Applicant: EBSCO INDUSTRIES, INC
    Inventors: Jeff Garrison, Bart Stephens, Alex Ng, Patrick Cheung
  • Patent number: 9160347
    Abstract: A method and apparatus for operating an electronic device is provided. The electronic device, which includes a phase lock loop (PLL) receives sensor indicators from at least one sensor. Upon receiving sensor indicators, the device identifies a motion indicator based on the sensor indicators. A parameter of the PLL is adjusted based on the motion indicator, the PLL having at least one component susceptible to microphonics. When the PLL includes a charge pump, a parameter that may be adjusted is a pump current of the charge pump. When the PLL further comprises an oscillator for generating a reference signal, the parameter that may be adjusted is a trim of the oscillator.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: October 13, 2015
    Assignee: Symbol Technologies, LLC
    Inventors: Irfan Kadri, Chu Pang Alex Ng
  • Publication number: 20150182866
    Abstract: A toy horse having a horse body, wherein the horse body includes a saddle board, two side boards, each side board being provided with a straight horse-back panel on its top, the two side boards being arranged opposite to each other symmetrically, which makes the horse-back panel of the two side boards being coplanar, the two side boards being removably installed on the saddle board, which makes the horse-back panel of the two side boards being abutted against the bottom of the saddle board, and the bottom of two side boards being shaped curly. The toy horse allows for portability of carry, convenience of assemble and comfortableness of ride.
    Type: Application
    Filed: January 2, 2015
    Publication date: July 2, 2015
    Inventors: Ping Fun Alex NG, KIN WAI HO