Patents by Inventor Alex Pasternak

Alex Pasternak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10429281
    Abstract: A molding apparatus for producing a biological tissue embedded in a block of an embedding material. The molding apparatus comprising a mold comprising a compartment configured for containing the embedding material. The compartment having a compartment floor and at least one wall extending upwards from said compartment floor. The compartment comprises at least one depression extending downwards from the compartment floor. The molding apparatus further comprising a sample sheet configured to attach to the biological tissue and hold the biological tissue thereon. The sample sheet being further dimensioned to be positioned in the compartment and to be constrained to the position thereof, at least along one direction, by the compartment. The depression is configured for accepting the biological tissue at least partially therein.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: October 1, 2019
    Assignee: UC-CARE LTD.
    Inventors: Alex Pasternak, Keren Shapira-Schweitzer
  • Patent number: 10383607
    Abstract: A tissue handling device is disclosed. A tissue collecting device is disclosed. A cassette for handling biological tissues is disclosed. A tissue dyeing device is disclosed. A method for handling biological tissues is disclosed. A method for dyeing biological tissues is disclosed.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: August 20, 2019
    Assignee: UC-CARE LTD.
    Inventors: Alex Pasternak, Keren Shapira-Schweizer, Shaike Schatzberger
  • Patent number: 10092279
    Abstract: A system further comprises a processing unit functionally associated with the display, wherein the processing unit comprises an image processing module. The system further comprises a camera functionally associated with the processing unit via a communication channel for transferring images from the camera to the processing unit and configured to obtain images of a biopsy sample obtained from the body of the patient. The processing unit is configured to receive image data from an imaging modality capable of obtaining images of internal patient's body parts not directly visible from outside the body, and to display to a user on a display images related to the image data. The processing unit is further configured to generate, from at least one image of a biopsy sample and using the image processing module, a processed image related to the biopsy sample, and to display the processed image on the display.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: October 9, 2018
    Assignee: UC-CARE LTD.
    Inventors: Alex Pasternak, Tomer Schatzberger, Shaike Schatzberger, Moshe Ebenstein
  • Patent number: 9892557
    Abstract: An integrated system for facilitating local treatment in an organ and capable of universally interfacing with other devices and systems is provided. The integrated system comprises an imaging system interface module configured to functionally associate with an imaging system capable of presenting to a user, through a user-interface device, parameters indicating a mode of operation of the imaging system. The imaging system interface module is configured to receive at least one of the parameters, to interpret such parameter and to allow the integrated system to assume a mode of operation according the parameter. The integrated system further comprises a treatment tool interface module, configured to receive and detect a treatment event signal from a portable treatment tool. The treatment event signal indicates a treatment event, thereby allowing establishing a time of the treatment event and thereby establishing a locality of a treatment provided to the organ by the portable treatment tool.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: February 13, 2018
    Assignee: UC-CARE LTD.
    Inventors: Alex Pasternak, Roni Zvuloni, Tomer Schatzberger, Shaike Schatzberger, Keren Shapira-Schweizer, Moshe Ebenstein, Michael Cohen
  • Patent number: 9708336
    Abstract: The present invention relates to compounds of formula (I) that are metallo-?-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with ?-lactam antibiotics for overcoming resistance.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: July 18, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Mihir Mandal, Haifeng Tang, Li Xiao, Jing Su, Guoqing Li, Shu-Wei Yang, Weidong Pan, Haiqun Tang, Reynalda DeJesus, Jacqueline Hicks, Matthew Lombardo, Hong Chu, William Hagmann, Alex Pasternak, Xin Gu, Jinlong Jiang, Shuzhi Dong, Fa-Xiang Ding, Clare London, Dipshikha Biswas, Katherine Young, David N. Hunter, Zhiqiang Zhao, Dexi Yang
  • Publication number: 20160333021
    Abstract: The present invention relates to compounds of formula (I) that are metallo-?-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with ?-lactam antibiotics for overcoming resistance.
    Type: Application
    Filed: January 16, 2015
    Publication date: November 17, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Mihir Mandal, Haifeng Tang, Li Xiao, Jing Su, Guoqing Li, Shu-Wei Yang, Weidong Pan, Haiqun Tang, Reynalda DeJesus, Jacqueline Hicks, Matthew Lombardo, Hong Chu, William Hagmann, Alex Pasternak, Xin Gu, Jinlong Jiang, Shuzhi Dong, Fa-Xiang Ding, Clare London, Dipshikha Biswas, Katherine Young, David N. Hunter, Zhiqiang Zhao, Dexi Yang
  • Publication number: 20160242748
    Abstract: A tissue handling device is disclosed. A tissue collecting device is disclosed. A cassette for handling biological tissues is disclosed. A tissue dyeing device is disclosed. A method for handling biological tissues is disclosed. A method for dyeing biological tissues is disclosed.
    Type: Application
    Filed: May 3, 2016
    Publication date: August 25, 2016
    Inventors: Alex Pasternak, Keren Shapira-Schweizer, Shaike Schatzberger
  • Publication number: 20160169778
    Abstract: A molding apparatus for producing a biological tissue embedded in a block of an embedding material. The molding apparatus comprising a mold comprising a compartment configured for containing the embedding material. The compartment having a compartment floor and at least one wall extending upwards from said compartment floor. The compartment comprises at least one depression extending downwards from the compartment floor. The molding apparatus further comprising a sample sheet configured to attach to the biological tissue and hold the biological tissue thereon. The sample sheet being further dimensioned to be positioned in the compartment and to be constrained to the position thereof, at least along one direction, by the compartment. The depression is configured for accepting the biological tissue at least partially therein.
    Type: Application
    Filed: February 1, 2016
    Publication date: June 16, 2016
    Inventors: Alex PASTERNAK, Keren SHAPIRA-SCHWEITZER
  • Patent number: 9341551
    Abstract: A tissue handling device is disclosed. A tissue collecting device is disclosed. A cassette for handling biological tissues is disclosed. A tissue dyeing device is disclosed. A method for handling biological tissues is disclosed. A method for dyeing biological tissues is disclosed.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: May 17, 2016
    Assignee: UC-CARE LTD.
    Inventors: Alex Pasternak, Keren Shapira-Schweizer, Shaike Schatzberger
  • Publication number: 20160030021
    Abstract: A system further comprises a processing unit functionally associated with the display, wherein the processing unit comprises an image processing module. The system further comprises a camera functionally associated with the processing unit via a communication channel for transferring images from the camera to the processing unit and configured to obtain images of a biopsy sample obtained from the body of the patient. The processing unit is configured to receive image data from an imaging modality capable of obtaining images of internal patient's body parts not directly visible from outside the body, and to display to a user on a display images related to the image data. The processing unit is further configured to generate, from at least one image of a biopsy sample and using the image processing module, a processed image related to the biopsy sample, and to display the processed image on the display.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 4, 2016
    Inventors: Alex PASTERNAK, Tomer SCHATZBERGER, Shaike SCHATZBERGER, Moshe EBENSTEIN
  • Patent number: 9250167
    Abstract: A mold for producing a biological tissue embedded in a block of an embedding material is provided. The mold comprises a compartment having a compartment floor and a depression extending downwards from the compartment floor. A molding apparatus, comprising a mold and a press for pressing a sample sheet onto the compartment floor of the mold is provided. The press comprises a foot configured to enter at least partially into the compartment and press a sample tissue, at least partially into the depression. A method of embedding a biological tissue in an embedding material using a mold as described herein is provided. A cleaning device configured for removing excess embedding materials from the press of the molding apparatus is provided.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: February 2, 2016
    Assignee: UC-CARE LTD.
    Inventors: Alex Pasternak, Keren Schweizer
  • Publication number: 20150045648
    Abstract: An integrated system for facilitating local treatment in an organ and capable of universally interfacing with other devices and systems is provided. The integrated system comprises an imaging system interface module configured to functionally associate with an imaging system capable of presenting to a user, through a user-interface device, parameters indicating a mode of operation of the imaging system. The imaging system interface module is configured to receive at least one of the parameters, to interpret such parameter and to allow the integrated system to assume a mode of operation according the parameter. The integrated system further comprises a treatment tool interface module, configured to receive and detect a treatment event signal from a portable treatment tool. The treatment event signal indicates a treatment event, thereby allowing establishing a time of the treatment event and thereby establishing a locality of a treatment provided to the organ by the portable treatment tool.
    Type: Application
    Filed: January 24, 2013
    Publication date: February 12, 2015
    Inventors: Alex Pasternak, Roni Zvuloni, Tomer Schatzberger, Shaike Schatzberger, Keren Shapira-Schweizer, Moshe Ebenstein, Michael Cohen
  • Publication number: 20150008616
    Abstract: A mold for producing a biological tissue embedded in a block of an embedding material is provided. The mold comprises a compartment having a compartment floor and a depression extending downwards from the compartment floor. A molding apparatus, comprising a mold and a press for pressing a sample sheet onto the compartment floor of the mold is provided. The press comprises a foot configured to enter at least partially into the compartment and press a sample tissue, at least partially into the depression. A method of embedding a biological tissue in an embedding material using a mold as described herein is provided. A cleaning device configured for removing excess embedding materials from the press of the molding apparatus is provided.
    Type: Application
    Filed: December 17, 2013
    Publication date: January 8, 2015
    Applicant: UC-CARE LTD.
    Inventors: Alex Pasternak, Keren Schweizer
  • Publication number: 20140377148
    Abstract: A tissue handling device is disclosed. A tissue collecting device is disclosed. A cassette for handling biological tissues is disclosed. A tissue dyeing device is disclosed. A method for handling biological tissues is disclosed. A method for dyeing biological tissues is disclosed.
    Type: Application
    Filed: January 10, 2013
    Publication date: December 25, 2014
    Inventors: Alex Pasternak, Keren Shapira-Schweizer, Shaike Schatzberger