Abstract: Apparatus including a refrigeration system, a geothermal system, and a refrigerant flow control apparatus connected between the refrigeration system and the geothermal system, wherein a first valve system is selectively actuatable to (i) in a first operation mode cause the refrigerant from a refrigerant circuit to flow through a first heat exchanger, with no refrigerant flow through a second heat exchanger, (ii) in a second operation mode cause the refrigerant from the refrigerant circuit to flow first through the first heat exchanger and then through the second heat exchanger in a first refrigerant flow direction, (iii) in a third operation mode cause the refrigerant from the refrigerant circuit to flow through the second heat exchanger, with no refrigerant flow through the first heat exchanger, and (iv) in a fourth operation mode cause the refrigerant from the refrigerant circuit to flow first through the second heat exchanger and then through the first heat exchanger in a second refrigerant flow direction.

Abstract: An apparatus connected to a refrigeration system and a geothermal system including: a first refrigerant connection connecting a compressor discharge line of a refrigerant circuit of a refrigeration system to a first side of a first heat exchanger, the first side of the first heat exchanger being couplable to the refrigerant and a second side of the first heat exchanger being couplable to ambient air, a second refrigerant connection connecting the first side of the first heat exchanger to a first side of a second heat exchanger, a second side of the second heat exchanger being couplable to a working fluid in a geothermal system, a third refrigerant connection connecting the first side of the second heat exchanger to a liquid return line of the refrigeration circuit, a first refrigerant interconnection that interconnects the first refrigerant connection with the second refrigerant connection, a second refrigerant interconnection that interconnects the second refrigerant connection with the third refrigerant con

Abstract: The present invention relates to regulation of IgE-receptor-mediated mast cell degranulation. More particularly, the present invention is directed to nucleic acids encoding CD43 (also called leukosialin or leukocyte large sialoglycoprotein), which is involved in modulation of IgE-receptor-mediated mast cell degranulation. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions, antibodies, siRNA, antisense nucleic acids, and ribozymes, that modulate IgE-receptor-mediated mast cell degranulation via modulation of CD43 and CD43-related signal transduction; as well as to the use of expression profiles and compositions in diagnosis and therapy related to diseases such as allergies and asthma.