Patents by Inventor Alex S. Goldstein

Alex S. Goldstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitor compounds for male contraception
    Patent number: 11548875
    Abstract: Pyrazole compounds and piperazine compounds that are inhibitors of ALDH1A1 and ALDH1A2 and methods for using the pyrazole compounds and piperazine compounds in male contraceptive compositions for preventing spermatogenesis.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: January 10, 2023
    Assignee: University of Washington
    Inventors: Alex S. Goldstein, John K. Amory, Jisun Paik, Michael Haenisch, Nina Isoherranen, Piper Treuting, Charles H. Muller
  • INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION
    Publication number: 20210332030
    Abstract: Pyrazole compounds and piperazine compounds that are inhibitors of ALDH1A1 and ALDH1A2 and methods for using the pyrazole compounds and piperazine compounds in male contraceptive compositions for preventing spermatogenesis.
    Type: Application
    Filed: December 12, 2019
    Publication date: October 28, 2021
    Applicant: University of Washington
    Inventors: Alex S. Goldstein, John K. Amory, Jisun Paik, Michael Haenisch, Nina Isoherranen, Piper Treuting, Charles H. Muller
  • Therapeutic delivery using compounds self-assembled into high axial ratio microstructures
    Patent number: 6180114
    Abstract: Therapeutic complexes comprising plural therapeutic compounds self assembled into high axial ratio microstructures are described. The therapeutic complexes satisfy the formula HARM-Th, wherein HARM is a high axial ratio forming material and Th is a therapeutic coupled to or associated with the HARM. The therapeutic complexes also can satisfy the formula HARM-S-Th, wherein S is a spacer. Release of the therapeutic by the complex generally follows either 0-order kinetics or psuedo-first order kinetics. A method for delivering therapeutics to oransims, particularly humans, also is described. The method comprises administering an effective amount of (1) a ligand, such as a therapeutic, self-assembled into a HAR microstructure, or (2) a ligand, such as a therapeutic, coupled to or associated with a material capable of thereafter self-assembling into a high axial ratio microstructure, to the mammal.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: January 30, 2001
    Assignee: University of Washington
    Inventors: Paul Yager, Michael H. Gelb, Anatoly N. Lukyanov, Alex S. Goldstein, Mary L. Disis
  • Therapeutic delivery using compounds self-assembled into high axial ratio microstructures
    Patent number: 5851536
    Abstract: Therapeutic agents comprising plural therapeutic compounds self assembled into high axial ratio microstructures are described. The threapeutic compounds satisfy the formula HARFM-Th, wherein HARFM is a high axial ratio forming material and Th is a therapeutic associated with the HARFM. The therapeutic agent also can satisfy the formula HARFM-S-Th, wherein S is a spacer. Release of the therapeutic by the agent generally follows either 0-order kinetics or psuedofirst order kinetics. A method for delivering drugs to animals or persons also is described. The method comprises administering an effective amount of a therapeutic self-assembled into an HAR microstructure to the animal or person.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: December 22, 1998
    Assignee: University of Washington
    Inventors: Paul Yager, Michael H. Gelb, Paul A. Carlson, Kyujin C. Lee, Anatoly N. Lukyanov, Alex S. Goldstein