Patents by Inventor Alex SCHEEPERS

Alex SCHEEPERS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of separating Factor VIII from blood products
    Patent number: 10889630
    Abstract: The invention provides a method for separating a Factor VIII (FVIII) protein from a first composition comprising the FVIII protein, which contains at least the light chain of FVIII, and a von-Willebrand-Factor (vWF) protein which comprises at least the FVIII binding domain of vWF, wherein the FVIII protein can form a complex with the vWF protein, the method comprising the steps: contacting the first composition with an affinity resin comprising a ligand and a matrix, wherein the ligand has an affinity to the light chain of FVIII, and separating the affinity resin from the mixture to obtain a modified first composition and a second composition, wherein the second composition contains the affinity resin, and a complex of the FVIII protein and the vWF protein.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: January 12, 2021
    Assignee: OCTAPHARMA AG
    Inventors: Stefan Winge, Per Rosen, Alex Scheepers
  • METHOD OF SEPARATING FACTOR VIII FROM BLOOD PRODUCTS
    Publication number: 20200010532
    Abstract: The invention provides a method for separating a Factor VIII (FVIII) protein from a first composition comprising the FVIII protein, which contains at least the light chain of FVIII, and a von-Willebrand-Factor (vWF) protein which comprises at least the FVIII binding domain of vWF, wherein the FVIII protein can form a complex with the vWF protein, the method comprising the steps: contacting the first composition with an affinity resin comprising a ligand and a matrix, wherein the ligand has an affinity to the light chain of FVIII, and separating the affinity resin from the mixture to obtain a modified first composition and a second composition, wherein the second composition contains the affinity resin, and a complex of the FVIII protein and the vWF protein.
    Type: Application
    Filed: February 10, 2017
    Publication date: January 9, 2020
    Inventors: Stefan WINGE, Per ROSEN, Alex SCHEEPERS