Patents by Inventor Alex Vilensky

Alex Vilensky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and intermediates for production of cabergoline and related compounds
    Patent number: 6696568
    Abstract: A process for preparation of N-(ergoline-8&bgr;-carbonyl)ureas of the formula [I] their stereoisomers as well as acid addition salts thereof which process comprises silylating an ergoline-8&bgr;-carboxamide of the formula [2], their stereoisomers as well as metal or ammonium salts or acid addition salts thereof and reacting the resultant product with an isocyanates R1N═C═O [5] wherein R1 is selected from alkyl having from 1 to 4 carbon atoms, cyclohexyl, phenyl, and dimethylamino alkyl group —(CH2)nNMe2 in which n is an integer, R2 is selected from hydrogen, alkyl having from 1 to 4 carbon atoms, cyclohexyl, phenyl, dimethylamino alkyl group —(CH2)nNMe2 in which n is an integer, pyridyl, pyrimidyl, pyrazinyl, pyridazinyl, thiazolyl or thiadiazolyl, R3 represent a hydrocarbon group having from 1 to 4 carbon atoms, and R4 is selected from hydrogen, halogen, methylthio and phenylthio group;; followed by desilylation.
    Type: Grant
    Filed: April 16, 2001
    Date of Patent: February 24, 2004
    Assignee: Finetech Ltd.
    Inventors: Arie L. Gutman, Gennadiy Nisnevich, Igor Ruchman, Boris Tishin, Alex Vilensky, Boris Pertsikov
  • Novel process and intermediates for production of cabergoline and related compounds
    Publication number: 20020177709
    Abstract: A process for preparation of N-(ergoline-8&bgr;-carbonyl)ureas of the formula [I] their stereoisomers as well as acid addition salts thereof which process comprises silylating an ergoline-8&bgr;-carboxamide of the formula [2], 1
    Type: Application
    Filed: April 16, 2001
    Publication date: November 28, 2002
    Inventors: Arie L. Gutman, Gennadiy Nisnevich, Igor Rukhman, Boris Tishin, Alex Vilensky, Boris Pertsikov