Patents by Inventor Alexa E. Richardson

Alexa E. Richardson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Positive modulators of the muscarinic acetylcholine receptor M4
    Patent number: 12552790
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Grant
    Filed: December 26, 2024
    Date of Patent: February 17, 2026
    Assignee: Vanderbilt University
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
    Publication number: 20260035366
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Application
    Filed: August 27, 2025
    Publication date: February 5, 2026
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • Positive modulators of the muscarinic acetylcholine receptor M4
    Patent number: 12448380
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Grant
    Filed: December 26, 2024
    Date of Patent: October 21, 2025
    Assignee: Vanderbilt University
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • Positive modulators of the muscarinic acetylcholine receptor M4
    Patent number: 12344608
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Grant
    Filed: June 21, 2024
    Date of Patent: July 1, 2025
    Assignee: Vanderbilt University
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
    Publication number: 20250136600
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Application
    Filed: December 26, 2024
    Publication date: May 1, 2025
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
    Publication number: 20250122200
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Application
    Filed: December 26, 2024
    Publication date: April 17, 2025
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
    Publication number: 20250122201
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Application
    Filed: December 26, 2024
    Publication date: April 17, 2025
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
    Publication number: 20250122199
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Application
    Filed: December 26, 2024
    Publication date: April 17, 2025
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
    Publication number: 20250122198
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Application
    Filed: December 26, 2024
    Publication date: April 17, 2025
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long
  • POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
    Publication number: 20250011320
    Abstract: Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.
    Type: Application
    Filed: June 21, 2024
    Publication date: January 9, 2025
    Inventors: Craig W. Lindsley, Darren W. Engers, Kayla J. Temple, Alison R. Gregro, Alexa E. Richardson, Madeline F. Long