Patents by Inventor Alexander A. Chubykin

Alexander A. Chubykin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SENSOR FOR HYPERSPECTRAL IMAGING BASED ON A METASURFACE-INTEGRATED LIGHT DETECTOR ARRAY
    Publication number: 20200025610
    Abstract: A spectroscopic microscope device, comprising at least one array of metasurfaces, and at least one CCD array integrated with the array of metasurfaces. The metasurfaces in the array are configured to separately direct LCP an RCP components of light incident on the metasurface to separate pixels in the CCD array.
    Type: Application
    Filed: March 22, 2019
    Publication date: January 23, 2020
    Applicant: Purdue Research Foundation
    Inventors: Rohith Chandrasekar, Amr Shaltout, Vladimir Shalaev, Alexander Chubykin, Alexei Lagoutchev
  • Systems and methods for automated image-guided patch-clamp electrophysiology in vitro
    Patent number: 10324080
    Abstract: Automated, image-guided systems for automatically performing in vitro cell patch clamping are provided. The systems are configured for use with a patch-clamp arrangement and include a camera system for providing images from tissues under investigation and a computer to execute calibration, detection, and whole-cell patching algorithms based on the collected image data. Automated methods for carrying out in vitro cell patch clamping using this automated, image-guided system are also provided and include using images to automatically calibrate a manipulator relative to a tissue of interest, detect and extract coordinates for a plurality of cells, and utilizing the coordinates with a patch-clamp arrangement to automatically move a manipulator directly above each of the plurality of cells and initiate the performance of an automated patch clamp mechanism for each of the plurality of cells driven by the system.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: June 18, 2019
    Assignee: Purdue Research Foundation
    Inventors: Alexander A. Chubykin, Zhaolun Su, Qiuyu Wu
  • SYSTEMS AND METHODS FOR AUTOMATED IMAGE-GUIDED PATCH-CLAMP ELECTROPHYSIOLOGY IN VITRO
    Publication number: 20170138926
    Abstract: Automated, image-guided systems for automatically performing in vitro cell patch clamping are provided. The systems are configured for use with a patch-clamp arrangement and include a camera system for providing images from tissues under investigation and a computer to execute calibration, detection, and whole-cell patching algorithms based on the collected image data. Automated methods for carrying out in vitro cell patch clamping using this automated, image-guided system are also provided and include using images to automatically calibrate a manipulator relative to a tissue of interest, detect and extract coordinates for a plurality of cells, and utilizing the coordinates with a patch-clamp arrangement to automatically move a manipulator directly above each of the plurality of cells and initiate the performance of an automated patch clamp mechanism for each of the plurality of cells driven by the system.
    Type: Application
    Filed: November 16, 2016
    Publication date: May 18, 2017
    Inventors: Alexander A. Chubykin, Zhaolun Su, Qiuyu Wu