Patents by Inventor Alexander A. Khorlin
Alexander A. Khorlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11235323Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: August 30, 2019Date of Patent: February 1, 2022Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
-
Publication number: 20200197934Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: August 30, 2019Publication date: June 25, 2020Inventors: Joseph AMSHEY, Daniel BEZDEK, Espir KAHATT, Alexander KHORLIN, Lance PARSONS, Todd PETERSON, Timothy POWERS, Michael THACKER, Timothy UPDYKE, Kornelija ZGONC
-
Patent number: 10434509Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: September 28, 2017Date of Patent: October 8, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
-
Patent number: 10274460Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.Type: GrantFiled: March 6, 2015Date of Patent: April 30, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Ian Walton, Achim Karger, Alexander Khorlin, Michael Simon, Adam Sannicandro, Alexander Dukhovny, Robert Cobene, Dan Kline, John Dixon
-
Publication number: 20180111121Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: September 28, 2017Publication date: April 26, 2018Inventors: Joseph AMSHEY, Daniel BEZDEK, Espir KAHATT, Alexander KHORLIN, Lance PARSONS, Todd PETERSON, Timothy POWERS, Michael THACKER, Timothy UPDYKE, Kornelija ZGONC
-
Patent number: 9808799Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: August 19, 2014Date of Patent: November 7, 2017Assignee: Life Technologies CorporationInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
-
Publication number: 20170176385Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.Type: ApplicationFiled: March 6, 2015Publication date: June 22, 2017Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Ian Walton, Achim Karger, Alexander Khorlin, Michael Simon, Adam Sannicandro, Alexander Dukhovny, Robert Cobene, Dan Kline, John Dixon
-
Publication number: 20150044758Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: August 19, 2014Publication date: February 12, 2015Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
-
Patent number: 8845984Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: September 13, 2012Date of Patent: September 30, 2014Assignee: Life Technologies CorporationInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
-
Patent number: 8404198Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: August 27, 2009Date of Patent: March 26, 2013Assignee: Life Technologies CorporationInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Korneija Zgonc
-
Publication number: 20130040376Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: September 13, 2012Publication date: February 14, 2013Applicant: LIFE TECHNOLOGIES COPORATIONInventors: Joseph AMSHEY, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Tacher, Timothy Updyke, Kornelija Zgonc
-
Publication number: 20100120129Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: August 27, 2009Publication date: May 13, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
-
Patent number: 7250157Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.Type: GrantFiled: October 14, 2005Date of Patent: July 31, 2007Assignee: Applied Genetics Incorporated DermaticsInventors: David A. Brown, Alexander A. Khorlin, Krystyna Lesiak, Wu Yun Ren
-
Patent number: 7064218Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.Type: GrantFiled: December 24, 2002Date of Patent: June 20, 2006Assignee: Genelabs Technologies, Inc.Inventors: Natalia B. Dyatkina, Dong-Fang Shi, Christopher Don Roberts, Mark Douglas Velligan, Sebastian Johannes Reinhard Liehr, Janos Botyanszki, Wentao Zhang, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
-
Publication number: 20060120976Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.Type: ApplicationFiled: October 14, 2005Publication date: June 8, 2006Applicant: Applied Genetics Incorporated DermaticsInventors: David Brown, Alexander Khorlin, Krystyna Lesiak, Wu Ren
-
Patent number: 6955804Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.Type: GrantFiled: September 22, 2003Date of Patent: October 18, 2005Assignee: Applied Genetics Incorporated DematicsInventors: David A. Brown, Alexander A. Khorlin, Krystyna Lesiak, Wu Yun Ren
-
Patent number: 6906103Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.Type: GrantFiled: October 23, 2002Date of Patent: June 14, 2005Assignee: Genelabs Technologies, Inc.Inventors: Wentao Zhang, Sebastian Johannes Reinhard Liehr, Mark Douglas Velligan, Natalia B. Dyatkina, Janos Botyanszki, Dong-Fang Shi, Christopher Don Roberts, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
-
Patent number: 6849713Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.Type: GrantFiled: June 26, 2001Date of Patent: February 1, 2005Assignee: Genelabs Technologies, Inc.Inventors: Wentao Zhang, Sebastian Johannes Reinhard Liehr, Mark Douglas Velligan, Natalia B. Dyatkina, Janos Botyanszki, Dong-Fang Shi, Christopher Don Roberts, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
-
Publication number: 20040241872Abstract: An optical detection liquid handling robot, including: a frame; a X-Y-Z robot connected to the frame; a plurality of liquid aspiration and dispensing nozzles connected to the X-Y-Z robot; a positioning system configured to position the X-Y-Z robot relative to the frame, thereby positioning the plurality of liquid aspiration and dispensing nozzles relative to the frame; a flow cell in each of the liquid aspiration and dispensing nozzles; a fiber optic probe in communication with each of the flow cells; and a spectrophotometer, wherein each of the fiber optic probes are multiplexed to the spectrophotometer.Type: ApplicationFiled: March 16, 2004Publication date: December 2, 2004Applicant: QIAGEN Operon, Inc.Inventors: Ronald J. Wegrzyn, Alexander A. Khorlin
-
Publication number: 20040067209Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.Type: ApplicationFiled: September 22, 2003Publication date: April 8, 2004Applicant: Applied Genetics Incorporated DermaticsInventors: David A. Brown, Alexander A. Khorlin, Krystyna Lesiak, Wu Yun Ren