Patents by Inventor Alexander A. Khorlin

Alexander A. Khorlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11235323
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: February 1, 2022
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
  • Publication number: 20200197934
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Application
    Filed: August 30, 2019
    Publication date: June 25, 2020
    Inventors: Joseph AMSHEY, Daniel BEZDEK, Espir KAHATT, Alexander KHORLIN, Lance PARSONS, Todd PETERSON, Timothy POWERS, Michael THACKER, Timothy UPDYKE, Kornelija ZGONC
  • Patent number: 10434509
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: October 8, 2019
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
  • Patent number: 10274460
    Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: April 30, 2019
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Ian Walton, Achim Karger, Alexander Khorlin, Michael Simon, Adam Sannicandro, Alexander Dukhovny, Robert Cobene, Dan Kline, John Dixon
  • Publication number: 20180111121
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Application
    Filed: September 28, 2017
    Publication date: April 26, 2018
    Inventors: Joseph AMSHEY, Daniel BEZDEK, Espir KAHATT, Alexander KHORLIN, Lance PARSONS, Todd PETERSON, Timothy POWERS, Michael THACKER, Timothy UPDYKE, Kornelija ZGONC
  • Patent number: 9808799
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: November 7, 2017
    Assignee: Life Technologies Corporation
    Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
  • Publication number: 20170176385
    Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.
    Type: Application
    Filed: March 6, 2015
    Publication date: June 22, 2017
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Ian Walton, Achim Karger, Alexander Khorlin, Michael Simon, Adam Sannicandro, Alexander Dukhovny, Robert Cobene, Dan Kline, John Dixon
  • Publication number: 20150044758
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 12, 2015
    Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
  • Patent number: 8845984
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: September 30, 2014
    Assignee: Life Technologies Corporation
    Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
  • Patent number: 8404198
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: March 26, 2013
    Assignee: Life Technologies Corporation
    Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Korneija Zgonc
  • Publication number: 20130040376
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Application
    Filed: September 13, 2012
    Publication date: February 14, 2013
    Applicant: LIFE TECHNOLOGIES COPORATION
    Inventors: Joseph AMSHEY, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Tacher, Timothy Updyke, Kornelija Zgonc
  • Publication number: 20100120129
    Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.
    Type: Application
    Filed: August 27, 2009
    Publication date: May 13, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
  • Patent number: 7250157
    Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: July 31, 2007
    Assignee: Applied Genetics Incorporated Dermatics
    Inventors: David A. Brown, Alexander A. Khorlin, Krystyna Lesiak, Wu Yun Ren
  • Patent number: 7064218
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: June 20, 2006
    Assignee: Genelabs Technologies, Inc.
    Inventors: Natalia B. Dyatkina, Dong-Fang Shi, Christopher Don Roberts, Mark Douglas Velligan, Sebastian Johannes Reinhard Liehr, Janos Botyanszki, Wentao Zhang, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Publication number: 20060120976
    Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.
    Type: Application
    Filed: October 14, 2005
    Publication date: June 8, 2006
    Applicant: Applied Genetics Incorporated Dermatics
    Inventors: David Brown, Alexander Khorlin, Krystyna Lesiak, Wu Ren
  • Patent number: 6955804
    Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.
    Type: Grant
    Filed: September 22, 2003
    Date of Patent: October 18, 2005
    Assignee: Applied Genetics Incorporated Dematics
    Inventors: David A. Brown, Alexander A. Khorlin, Krystyna Lesiak, Wu Yun Ren
  • Patent number: 6906103
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: June 14, 2005
    Assignee: Genelabs Technologies, Inc.
    Inventors: Wentao Zhang, Sebastian Johannes Reinhard Liehr, Mark Douglas Velligan, Natalia B. Dyatkina, Janos Botyanszki, Dong-Fang Shi, Christopher Don Roberts, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Patent number: 6849713
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: February 1, 2005
    Assignee: Genelabs Technologies, Inc.
    Inventors: Wentao Zhang, Sebastian Johannes Reinhard Liehr, Mark Douglas Velligan, Natalia B. Dyatkina, Janos Botyanszki, Dong-Fang Shi, Christopher Don Roberts, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Publication number: 20040241872
    Abstract: An optical detection liquid handling robot, including: a frame; a X-Y-Z robot connected to the frame; a plurality of liquid aspiration and dispensing nozzles connected to the X-Y-Z robot; a positioning system configured to position the X-Y-Z robot relative to the frame, thereby positioning the plurality of liquid aspiration and dispensing nozzles relative to the frame; a flow cell in each of the liquid aspiration and dispensing nozzles; a fiber optic probe in communication with each of the flow cells; and a spectrophotometer, wherein each of the fiber optic probes are multiplexed to the spectrophotometer.
    Type: Application
    Filed: March 16, 2004
    Publication date: December 2, 2004
    Applicant: QIAGEN Operon, Inc.
    Inventors: Ronald J. Wegrzyn, Alexander A. Khorlin
  • Publication number: 20040067209
    Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.
    Type: Application
    Filed: September 22, 2003
    Publication date: April 8, 2004
    Applicant: Applied Genetics Incorporated Dermatics
    Inventors: David A. Brown, Alexander A. Khorlin, Krystyna Lesiak, Wu Yun Ren