Patents by Inventor Alexander Abbas

Alexander Abbas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HEPATOCELLULAR CARCINOMA MOLECULAR SUBTYPE CLASSIFICATION AND SUBTYPE SPECIFIC TREATMENTS FOR HEPATOCELLULAR CARCINOMA
    Publication number: 20250054631
    Abstract: A method for hepatocellular carcinoma (HCC) subtype classification and treatment may include identifying, for a liver epithelial cell lineage, one or more features associated with the liver epithelial cell lineage. The one or more features may be designated as representative of a molecular subtype associated with hepatocellular carcinoma (HCC) such as, for example, a cholangio-like subtype, a hepatocyte-like subtype, or a progenitor-like subtype. A patient may be determined to exhibit the molecular subtype if these features are detected within the tumor sample of the patient. Moreover, treatment for the patient may be determined based on the molecular subtype exhibited by the patient. For example, treatment for the patient may include additional therapies, such as an GPC3/CD3 bi-specific antibody, to overcome subtype-specific resistance to combination immunotherapy associated with the progenitor-like subtype. Related systems and computer program products are also provided.
    Type: Application
    Filed: October 28, 2024
    Publication date: February 13, 2025
    Inventors: Yinghui GUAN, Shan LU, Yulei WANG, Alexander ABBAS
  • METHODS AND COMPOSITIONS FOR DETECTING AUTOIMMUNE DISORDERS
    Publication number: 20160097098
    Abstract: The invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Application
    Filed: September 2, 2015
    Publication date: April 7, 2016
    Applicant: Genentech, Inc.
    Inventors: Alexander ABBAS, Barmak MODREK, Michael J. TOWNSEND
  • Methods for diagnosing and treating systemic lupus erythematosus
    Patent number: 9139878
    Abstract: This invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: September 22, 2015
    Assignee: Genentech, Inc.
    Inventors: Alexander Abbas, Barmak Modrek, Michael J. Townsend
  • Methods for detecting and treating systemic lupus erythematous
    Patent number: 8962249
    Abstract: The invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: February 24, 2015
    Assignee: Genentech, Inc.
    Inventors: Alexander Abbas, Barmak Modrek, Michael J. Townsend
  • Compositions and methods for the treatment of immune related diseases
    Publication number: 20140371086
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
    Type: Application
    Filed: May 29, 2014
    Publication date: December 18, 2014
    Inventors: Alexander Abbas, Hilary Clark, Wenjun Ouyang, P. Mickey Williams, William I. Wood, Thomas D. Wu
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES
    Publication number: 20140018250
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
    Type: Application
    Filed: July 13, 2012
    Publication date: January 16, 2014
    Inventors: Alexander ABBAS, Sarah C. Bodary, Hilary Clark, Jill R. Schoenfeld, P. Mickey Williams, William I. Wood, Thomas D. Wu
  • METHODS AND COMPOSITIONS FOR DETECTING AUTOIMMUNE DISORDERS
    Publication number: 20130338019
    Abstract: This invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Application
    Filed: March 11, 2013
    Publication date: December 19, 2013
    Inventors: Alexander ABBAS, Barmak MODREK, Michael J. TOWNSEND
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES
    Publication number: 20130165332
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
    Type: Application
    Filed: July 13, 2012
    Publication date: June 27, 2013
    Inventors: Alexander ABBAS, Hilary Clark, Wenjun Ouyang, P. Mickey Williams, William I. Wood, Thomas D. Wu
  • Methods and compositions for detecting autoimmune disorders
    Publication number: 20120295799
    Abstract: The invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Application
    Filed: December 21, 2011
    Publication date: November 22, 2012
    Applicant: Genentech, Inc.
    Inventors: Alexander Abbas, Barmak Modrek, Michael J. Townsend
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES
    Publication number: 20110245090
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
    Type: Application
    Filed: March 11, 2011
    Publication date: October 6, 2011
    Inventors: Alexander Abbas, Hilary Clark, Wenjun Ouyang, P. Mickey Williams, William I. Wood, Thomas D. Wu
  • Compositions and methods for the treatment of systemic lupus erythematosis
    Publication number: 20110142841
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
    Type: Application
    Filed: October 22, 2009
    Publication date: June 16, 2011
    Inventors: Alexander Abbas, Sarah C. Bodary, Hilary Clark, Jill R. Schoenfeld, P. Mickey Williams, William I. Wood, Thomas D. Wu
  • Methods and Compositions For Detecting Autoimmune Disorders
    Publication number: 20100279298
    Abstract: The invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Application
    Filed: March 30, 2010
    Publication date: November 4, 2010
    Applicant: Genentech, Inc.
    Inventor: Alexander Abbas
  • Methods and Compositions For Detecting Autoimmune Disorders
    Publication number: 20100267033
    Abstract: The invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Application
    Filed: March 30, 2010
    Publication date: October 21, 2010
    Applicant: Genentech, Inc.
    Inventors: Alexander Abbas, Barmak Modrek, Michael J. Townsend
  • PRO polypeptides for diagnosis of systemic lupus erythematosis
    Patent number: 7749695
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: July 6, 2010
    Inventors: Alexander Abbas, Sarah Bodary, Hilary Clark, P Mickey Williams, Thomas D Wu
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES
    Publication number: 20100034817
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
    Type: Application
    Filed: October 7, 2009
    Publication date: February 11, 2010
    Inventors: Alexander Abbas, Hilary Clark, Wenjun Ouyang, P. Mickey Williams, William I. Wood, Thomas D. Wu
  • Gene expression markers for inflammatory bowel disease
    Publication number: 20090186034
    Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
    Type: Application
    Filed: December 19, 2007
    Publication date: July 23, 2009
    Applicant: Genetech, Inc.
    Inventors: Alexander Abbas, Hilary Clark, Lauri Diehl
  • NOVEL COMPOSITION AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASE
    Publication number: 20090162350
    Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related disease.
    Type: Application
    Filed: July 29, 2005
    Publication date: June 25, 2009
    Inventors: Alexander Abbas, Hilary Clark, P. Mickey Williams, William I. Wood
  • Compositions and Methods for the Treatment of Systemic Lupus Erythematosis
    Publication number: 20090054300
    Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases
    Type: Application
    Filed: March 2, 2004
    Publication date: February 26, 2009
    Inventors: Alexander Abbas, Sarah C. Bodary, Hilary Clark, Jill R. Schoenfeld, P. Mickey Williams, William I. Wood, Thomas D. Wu
  • METHODS AND COMPOSITIONS FOR DETECTING AUTOIMMUNE DISORDERS
    Publication number: 20080318800
    Abstract: The invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Application
    Filed: February 20, 2008
    Publication date: December 25, 2008
    Applicant: Genentech, Inc.
    Inventor: Alexander ABBAS
  • METHODS AND COMPOSITIONS FOR DETECTING AUTOIMMUNE DISORDERS
    Publication number: 20080057503
    Abstract: The invention provides methods and compositions useful for detecting autoimmune disorders.
    Type: Application
    Filed: April 24, 2007
    Publication date: March 6, 2008
    Inventors: Alexander Abbas, Barmak Modrek, Michael Townsend