Patents by Inventor Alexander ALEXANDROV

Alexander ALEXANDROV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY OF HBV AND HDV INFECTION
    Publication number: 20220040178
    Abstract: The invention provides a composition comprising an inhibitor of Na+-taurocholate cotransporting polypeptide (NTCP) and a active ingredient selected from the group consisting of a nucleoside analogue such as lamivudine, telbivudine, or entecavir, a nucleotide analogue such as tenofovir, adefovir and an immunomodulator such as interferon alpha. The NTCP inhibitor inhibits HBV/HDV entry into a cell and is preferably derived from an HBV pre-S1 peptide. Also provided are methods of treating HBV and HDV infection, hepatitis B and D, or chronic hepatitis B and D.
    Type: Application
    Filed: March 23, 2021
    Publication date: February 10, 2022
    Applicant: MYR GMBH
    Inventor: Alexander ALEXANDROV
  • THERAPY OF ATHEROSCLEROSIS, PRIMARY BILIARY CIRRHOSIS AND NRLP3 INFLAMMASOME-ASSOCIATED DISEASE BY HTCP INHIBITORS
    Publication number: 20210196786
    Abstract: An inhibitor of Na+-taurocholate cotransporting polypeptide (NTCP) for use in a method of treatment of primary biliary cirrhosis, atherosclerosis, or an NRLP3 inflammasome-associated disease in a subject.
    Type: Application
    Filed: February 22, 2021
    Publication date: July 1, 2021
    Applicant: MYR GmbH
    Inventor: Alexander ALEXANDROV
  • Therapy of atherosclerosis, primary biliary cirrhosis and NRLP3 inflammasome-associated disease by HTCP inhibitors
    Patent number: 10925925
    Abstract: An inhibitor of Na+-taurocholate cotransporting polypeptide (NTCP) for use in a method of treatment of primary biliary cirrhosis, atherosclerosis, or an NRLP3 inflammasome-associated disease in a subject.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: February 23, 2021
    Assignee: MYR GMBH
    Inventor: Alexander Alexandrov
  • THERAPY OF ATHEROSCLEROSIS, PRIMARY BILIARY CIRRHOSIS AND NRLP3 INFLAMMASOME-ASSOCIATED DISEASE BY HTCP INHIBITORS
    Publication number: 20180296634
    Abstract: An inhibitor of Na+-taurocholate cotransporting polypeptide (NTCP) for use in a method of treatment of primary biliary cirrhosis, atherosclerosis, or an NRLP3 inflammasome-associated disease in a subject.
    Type: Application
    Filed: April 12, 2018
    Publication date: October 18, 2018
    Applicant: MYR GmbH
    Inventor: Alexander ALEXANDROV
  • COMBINATION THERAPY OF HBV AND HDV INFECTION
    Publication number: 20180228804
    Abstract: The invention provides a composition comprising an inhibitor of Na+-taurocholate cotransporting polypeptide (NTCP) and a active ingredient selected from the group consisting of a nucleoside analogue such as lamivudine, telbivudine, or entecavir, a nucleotide analogue such as tenofovir, adefovir and an immunomodulator such as interferon alpha. The NTCP inhibitor inhibits HBV/HDV entry into a cell and is preferably derived from an HBV pre-S1 peptide. Also provided are methods of treating HBV and HDV infection, hepatitis B and D, or chronic hepatitis B and D.
    Type: Application
    Filed: October 7, 2015
    Publication date: August 16, 2018
    Applicant: MYR GMBH
    Inventor: Alexander ALEXANDROV
  • COMPUTING DEVICE APPLICATIONS WITH AN AUTOMATICALLY ADAPTING USER INTERFACE
    Publication number: 20140035945
    Abstract: In one aspect, the present disclosure describes a method that may include determining, by a processor of a computing device, a platform of the computing device. Based at least in part upon the platform, the method may include altering, by the processor, a platform-independent presentation file. The method may include determining, by the processor, a platform-specific graphical user interface of a software application based at least in part on the platform-independent presentation file.
    Type: Application
    Filed: August 3, 2012
    Publication date: February 6, 2014
    Inventors: Todd Anglin, Alexander Alexandrov Gyoshev, Kamen Todorov Bandev