Abstract: A method of a virtual X-ray colonoscopy includes scanning (204) a dark-field contrast (144) insufflated colon lumen (140) with an X-ray scanner (110) configured for dark-field-contrast, which generates dark-field-contrasted projection data and attenuation projection data. The dark-field-contrasted projection data and the attenuation projection data are reconstructed (206) into one or more dark-field-contrasted images (148).

Abstract: A method of spectrally imaging an organ during an image-guided intervention is disclosed. Based on at least one first scan, a first image modality is obtained. A selection of a region of interest is obtained within the first image modality. Based on at least one second spectral scan of the organ, at least three second image modalities are obtained. A contrast value is calculated over the previously selected region of interest for all obtained second image modalities. The second image modality with the largest contrast value is selected for display. Alternatively, image modalities of the organ are displayed over time and the modalities for display are selected according to an imaging protocol which associates a lesion type and timestamp of a spectral scan with a modality having optimal contrast.

Abstract: A method of a virtual X-ray colonoscopy includes scanning (204) a dark-field contrast (144) insufflated colon lumen (140) with an X-ray scanner (110) configured for dark-field-contrast, which generates dark-field-contrasted projection data and attenuation projection data. The dark-field-contrasted projection data and the attenuation projection data are reconstructed (206) into one or more dark-field-contrasted images (148).