Patents by Inventor Alexander ANNALA

Alexander ANNALA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENCAPSULATED DIAGNOSTICS AND THERAPEUTICS IN NANOPARTICLES - CONJUGATED TO TROPIC CELLS AND METHODS FOR THEIR USE
    Publication number: 20190388474
    Abstract: A therapeutic or diagnostic delivery vehicle is provided. The delivery vehicle may include one or more particles, such as microparticles, nanoparticles and stimuli-responsive particles, conjugated to a tropic cell that targets at least one pathological entity or site. In addition. a pharmaceutical composition is provided. The pharmaceutical composition may include, among other things, a particle conjugated to a tropic cell such as those discussed above and at least one diagnostic or therapeutic agent, such as those described herein. In some aspects, the tropic cell may target at least one pathological entity or site. Further, methods for diagnosing, monitoring or treating a pathological condition in a subject are provided. Such methods may include administering a therapeutically effective amount of the pharmaceutical composition to a subject.
    Type: Application
    Filed: August 7, 2019
    Publication date: December 26, 2019
    Inventors: Karen ABOODY, Alexander ANNALA, Rachael MOONEY, Jacob BERLIN, Yiming WENG
  • Encapsulated diagnostics and therapeutics in nanoparticles—conjugated to tropic cells and methods for their use
    Patent number: 10426801
    Abstract: A therapeutic or diagnostic delivery vehicle is provided. The delivery vehicle may include one or more particles, such as microparticles, nanoparticles and stimuli-responsive particles, conjugated to a tropic cell that targets at least one pathological entity or site. In addition, a pharmaceutical composition is provided. The pharmaceutical composition may include, among other things, a particle conjugated to a tropic cell such as those discussed above and at least one diagnostic or therapeutic agent, such as those described herein. In some aspects, the tropic cell may target at least one pathological entity or site. Further, methods for diagnosing, monitoring or treating a pathological condition in a subject are provided. Such methods may include administering a therapeutically effective amount of the pharmaceutical composition to a subject.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: October 1, 2019
    Assignee: City of Hope
    Inventors: Karen Aboody, Alexander Annala, Rachael Mooney, Jacob Berlin, Yiming Weng
  • ENCAPSULATED DIAGNOSTICS AND THERAPEUTICS IN NANOPARTICLES - CONJUGATED TO TROPIC CELLS AND METHODS FOR THEIR USE
    Publication number: 20150056144
    Abstract: A therapeutic or diagnostic delivery vehicle is provided. The delivery vehicle may include one or more particles, such as microparticles, nanoparticles and stimuli-responsive particles, conjugated to a tropic cell that targets at least one pathological entity or site. In addition, a pharmaceutical composition is provided. The pharmaceutical composition may include, among other things, a particle conjugated to a tropic cell such as those discussed above and at least one diagnostic or therapeutic agent, such as those described herein. In some aspects, the tropic cell may target at least one pathological entity or site. Further, methods for diagnosing, monitoring or treating a pathological condition in a subject are provided. Such methods may include administering a therapeutically effective amount of the pharmaceutical composition to a subject.
    Type: Application
    Filed: April 18, 2014
    Publication date: February 26, 2015
    Inventors: Karen ABOODY, Alexander ANNALA, Rachael MOONEY, Jacob BERLIN, Yiming WENG