Patents by Inventor Alexander ASSMANN
Alexander ASSMANN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20250065009Abstract: The present invention provides an improved tissue adhesive to repair defects in soft tissue. Following ASTM standard tests, crosslinked methacryloyl-substituted gelatin hydrogels of the present invention (GelSEAL) were shown to exhibit adhesive properties, i.e. wound closure strength, shear resistance and burst pressure, that were superior to clinically used fibrin- and poly(ethylene glycol)-based glues. Chronic in vivo experiments in rats proved GelSEAL to effectively seal large lung leakages without additional sutures or staples, presenting improved performance as compared to fibrin and poly(ethylene glycol) glues. Furthermore, subcutaneous implantation in rats revealed high biocompatibility of GelSEAL as evidenced by low inflammatory host response.Type: ApplicationFiled: August 9, 2024Publication date: February 27, 2025Inventors: Ali Khademhosseini, Nasim Annabi, Alexander Assmann
-
Patent number: 12090246Abstract: The present invention provides an improved tissue adhesive to repair defects in soft tissue. Following ASTM standard tests, crosslinked methacryloyl-substituted gelatin hydrogels of the present invention (GelSEAL) were shown to exhibit adhesive properties, i.e. wound closure strength, shear resistance and burst pressure, that were superior to clinically used fibrin- and poly(ethylene glycol)-based glues. Chronic in vivo experiments in rats proved GelSEAL to effectively seal large lung leakages without additional sutures or staples, presenting improved performance as compared to fibrin and poly(ethylene glycol) glues. Furthermore, subcutaneous implantation in rats revealed high biocompatibility of GelSEAL as evidenced by low inflammatory host response.Type: GrantFiled: October 6, 2020Date of Patent: September 17, 2024Assignee: The Brigham and Women's Hospital, Inc.Inventors: Ali Khademhosseini, Nasim Annabi, Alexander Assmann
-
Patent number: 11542200Abstract: A composition may be suitable for flowable refractory materials and include calcium aluminate cement, a filler, a plasticizer in the form of a copolymer comprising polyether side chains, and a retarder having at least one acid. An article may include such a composition.Type: GrantFiled: June 25, 2019Date of Patent: January 3, 2023Inventors: Adolf Faerberboeck, Konrad Wutz, Alexander Assmann, Torben Gaedt
-
Patent number: 11387641Abstract: A fitting for receiving an insulated lead and a method for assembly thereof are provided. The fitting comprises an elongate member, a sleeve, a collar, and an insulator. The elongate member comprises a first end, a second end, and an interior surface defining an elongate cavity. The first end is open. The sleeve is configured to receive the insulated lead. The first end is configured to receive the sleeve. The collar is configured to compress the sleeve onto the insulated lead to form a seal between the insulated lead and the elongate member. The insulator is configured to inhibit electrical contact between an inner conductor of the insulated lead and the interior surface of the elongate member.Type: GrantFiled: June 15, 2020Date of Patent: July 12, 2022Assignee: CHROMALOX, INC.Inventors: Danny Rech, Walter Baus, Alexander Assmann
-
Publication number: 20210391700Abstract: A fitting for receiving an insulated lead and a method for assembly thereof are provided. The fitting comprises an elongate member, a sleeve, a collar, and an insulator. The elongate member comprises a first end, a second end, and an interior surface defining an elongate cavity. The first end is open. The sleeve is configured to receive the insulated lead. The first end is configured to receive the sleeve. The collar is configured to compress the sleeve onto the insulated lead to form a seal between the insulated lead and the elongate member. The insulator is configured to inhibit electrical contact between an inner conductor of the insulated lead and the interior surface of the elongate member.Type: ApplicationFiled: June 15, 2020Publication date: December 16, 2021Inventors: Danny Rech, Walter Baus, Alexander Assmann
-
Publication number: 20210261463Abstract: A composition may be suitable for flowable refractory materials and include calcium aluminate cement, a filler, a plasticizer in the form of a copolymer comprising polyether side chains, and a retarder having at least one acid. An article may include such a composition.Type: ApplicationFiled: June 25, 2019Publication date: August 26, 2021Applicant: BASF SEInventors: Adolf FAERBERBOECK, Konrad WUTZ, Alexander ASSMANN, Torben GAEDT
-
Publication number: 20210100928Abstract: The present invention provides an improved tissue adhesive to repair defects in soft tissue. Following ASTM standard tests, crosslinked methacryloyl-substituted gelatin hydrogels of the present invention (GelSEAL) were shown to exhibit adhesive properties, i.e. wound closure strength, shear resistance and burst pressure, that were superior to clinically used fibrin- and poly(ethylene glycol)-based glues. Chronic in vivo experiments in rats proved GelSEAL to effectively seal large lung leakages without additional sutures or staples, presenting improved performance as compared to fibrin and poly(ethylene glycol) glues. Furthermore, subcutaneous implantation in rats revealed high biocompatibility of GelSEAL as evidenced by low inflammatory host response.Type: ApplicationFiled: October 6, 2020Publication date: April 8, 2021Inventors: Ali Khademhosseini, Nasim Annabi, Alexander Assmann
-
Patent number: 10814032Abstract: The present invention provides an improved tissue adhesive to repair defects in soft tissue. Following ASTM standard tests, crosslinked methacryloyl-substituted gelatin hydrogels of the present invention (GelSEAL) were shown to exhibit adhesive properties, i.e. wound closure strength, shear resistance and burst pressure, that were superior to clinically used fibrin- and poly(ethylene glycol)-based glues. Chronic in vivo experiments in rats proved GelSEAL to effectively seal large lung leakages without additional sutures or staples, presenting improved performance as compared to fibrin and poly(ethylene glycol) glues. Furthermore, subcutaneous implantation in rats revealed high biocompatibility of GelSEAL as evidenced by low inflammatory host response.Type: GrantFiled: August 6, 2015Date of Patent: October 27, 2020Assignee: The Brigham and Women's Hospital, Inc.Inventors: Ali Khademhosseini, Nasim Annabi, Alexander Assmann
-
Patent number: 10144671Abstract: A process for hydrophobization of concrete or mortar using an aqueous dispersion containing an alkylketene dimer, at least one emulsifier and a condensation product of phenol sulfonic acid and formaldehyde, naphthalene sulfonic acid and formaldehyde, or naphthalene sulfonic acid, phenol, formaldehyde and urea; and the concrete or mortar obtainable by the process. The process allows effective mass and surface hydrophobization of concrete.Type: GrantFiled: October 23, 2015Date of Patent: December 4, 2018Assignee: BASF SEInventors: Uwe Gehrig, Alexander Assmann, Klaus Seip, Martin Pichler, Torben Gädt
-
Patent number: 9926233Abstract: The present invention relates to a construction chemical composition comprising Portland cement, a water retention agent, a dispersing agent, and a hardening accelerator comprising calcium-silicate-hydrate, as well as a mortar composition containing said construction chemical composition. Although the composition is based on Portland cement it has a pull-off strength after 6 h meeting the DIN requirements and can therefore be used as a fast setting tile mortar.Type: GrantFiled: December 17, 2015Date of Patent: March 27, 2018Assignee: BASF SEInventors: Alexander Assmann, Christian Biro, Christoph Hesse
-
Publication number: 20170275204Abstract: The present invention relates to a construction chemical composition comprising Portland cement, a water retention agent, a dispersing agent, and a hardening accelerator comprising calcium-silicate-hydrate, as well as a mortar composition containing said construction chemical composition. Although the composition is based on Portland cement it has a pull-off strength after 6 h meeting the DIN requirements and can therefore be used as a fast setting tile mortar.Type: ApplicationFiled: December 17, 2015Publication date: September 28, 2017Inventors: Alexander ASSMANN, Christian BIRO, Christoph HESSE
-
Publication number: 20170240468Abstract: The invention relates to a process for hydrophobization of concrete or mortar using an alkylketene dimer dispersion and to the concrete or mortar obtainable by the process of the invention. The process allows to achieve effective mass and surface hydrophobization of concrete.Type: ApplicationFiled: October 23, 2015Publication date: August 24, 2017Inventors: Uwe GEHRIG, Alexander ASSMANN, Klaus SEIP, Martin PICHLER, Torben GÄDT
-
Publication number: 20170232138Abstract: The present invention provides an improved tissue adhesive to repair defects in soft tissue. Following ASTM standard tests, crosslinked methacryloyl-substituted gelatin hydrogels of the present invention (GelSEAL) were shown to exhibit adhesive properties, i.e. wound closure strength, shear resistance and burst pressure, that were superior to clinically used fibrin- and poly(ethylene glycol)-based glues. Chronic in vivo experiments in rats proved GelSEAL to effectively seal large lung leakages without additional sutures or staples, presenting improved performance as compared to fibrin and poly(ethylene glycol) glues. Furthermore, subcutaneous implantation in rats revealed high biocompatibility of GelSEAL as evidenced by low inflammatory host response.Type: ApplicationFiled: August 6, 2015Publication date: August 17, 2017Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.Inventors: Ali KHADEMHOSSEINI, Nasim ANNABI, Alexander ASSMANN