Abstract: An apparatus and a method for packaging substantially plate-shaped or cuboid-shaped products in the food industry in a packaging material film, the apparatus having feeding devices for feeding products to a packaging station; guiding devices for feeding a blank of the packaging material film to the packaging station, wherein the product is inserted into the blank such that the packaging material film substantially wraps around the product; discharge devices for discharging the product from the packaging station in a wrapped state; and holding devices being movably configured and arranged to move with the product through the packaging station.

Abstract: A filter device having a filter housing (1), in which a replaceable filter element (7) is accommodated and which has a cover part (2), wherein the element material (9) of the filter element (7) extends between two end caps (13, 14) of the latter, is characterized in that the filter housing (1), which is formed as an outlet pipe (3), extends between both end caps (13, 14) as well.

Abstract: A method and device for producing individual strip-shaped objects. The method and device supply substantially rectangular sheets from which strip-shaped objects are to be formed. In forming the individual strips, the method and device separate an individual strip from the sheet along a front most groove, which forms a predetermined spacing between the individual consecutive separated strips for a subsequent onward conveying of the formed strips. Next, the method and device detect an actual position of each individually separated strip during the separation of the strips from the sheet, and corrects the position of the individual separated strips if the detected actual position of the strip does not correspond to a position which matches the predetermined spacing between the individual consecutive strips.

Abstract: The invention relates to a method and device for producing individual strip-shaped objects (strip S), in particular objects that are suitable for consumption, in particular sticks of chewing gum, said method and device having the following method steps and features; supplying substantially rectangular sheets (P), trots which the strip-shaped objects (S) are to be formed, wherein the length of the shorter sides of the sheets (P) corresponds substantially to the length of a strip-shaped object (S) to be formed, and wherein several grooves (R) which extend parallel to one another are arranged at identical spacings in the sheets (P) substantially parallel to the shorter sides of the sheets (P), wherein the spacing between two adjacently arranged grooves (R) in each case corresponds substantially to the width of a strip (S) to be formed; and forming the individual strips (S) from the sheets (P) which are supplied individually consecutively in their longitudinal direction.

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

Abstract: The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof.

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

Abstract: Described are heterobicyclic compounds such as 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]thiopyran 3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid amides, or benzo[b]thiophene-3-carboxylic acid amides and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of various diseases such as infectious diseases, including mycobacteriainduced infections and opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as compositions containing at least one heterobicyclic compound and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the heterobicyclic compound are disclosed.

Abstract: The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof.