Abstract: A method is provided for operating a first computer device, in which a source program code is generated which contains a functional model that is hierarchically composed of functions which are hierarchically composed of components, the visibility of the components within the functional model being determined by the hierarchy. Placeholders are used within the hierarchy for determined components and executable program code is generated, the placeholders being replaced by the determined components via a correspondingly executed mapping rule before executable program code is generated. This method allows the locality principle to be maintained, for example on experimental hardware.

Abstract: The present invention relates to compositions for oral administration. The invention preferably comprises at least one abuse-resistant drug delivery composition for delivering a drug having potential for dose dumping in alcohol, related methods of preparing these dosage forms, and methods of treating a patient in need thereof comprising administering the inventive compositions to the patient. Most preferably, the dosage form includes verapamil. These formulations have reduced potential for abuse. In another formulation, preferably the abuse relevant drug is an opioid and the non-abuse relevant drug is acetaminophen or ibuprofen. More preferably, the opioid is hydrocodone, and the non-abuse relevant analgesic is acetaminophen. In certain preferred embodiments, the dosage forms are characterized by resistance to solvent extraction; tampering, crushing or grinding.

Abstract: A method is provided for operating a first computer device, in which a source program code is generated which contains a functional model that is hierarchically composed of functions which are hierarchically composed of components, the visibility of the components within the functional model being determined by the hierarchy. Placeholders are used within the hierarchy for determined components and executable program code is generated, the placeholders being replaced by the determined components via a correspondingly executed mapping rule before executable program code is generated. This method allows the locality principle to be maintained, for example on experimental hardware.

Abstract: The present invention relates to compositions for oral administration. The invention preferably comprises at least one abuse-resistant drug delivery composition for delivering a drug having potential for dose dumping in alcohol, related methods of preparing these dosage forms, and methods of treating a patient in need thereof comprising administering the inventive compositions to the patient. Most preferably, the dosage form includes verapamil. These formulations have reduced potential for abuse. In another formulation, preferably the abuse relevant drug is an opioid and the non-abuse relevant drug is acetaminophen or ibuprofen. More preferably, the opioid is hydrocodone, and the non-abuse relevant analgesic is acetaminophen. In certain preferred embodiments, the dosage forms are characterized by resistance to solvent extraction; tampering, crushing or grinding.

Abstract: The present invention relates to compositions for oral administration. The invention preferably comprises at least one abuse-resistant drug delivery composition for delivering a drug having potential for dose dumping in alcohol, related methods of preparing these dosage forms, and methods of treating a patient in need thereof comprising administering the inventive compositions to the patient. Most preferably, the dosage form includes verapamil. These formulations have reduced potential for abuse. In another formulation, preferably the abuse relevant drug is an opioid and the non-abuse relevant drug is acetaminophen or ibuprofen. More preferably, the opioid is hydrocodone, and the non-abuse relevant analgesic is acetaminophen. In certain preferred embodiments, the dosage forms are characterized by resistance to solvent extraction; tampering, crushing or grinding.

Abstract: A method for activating functions of a certain application in which predefined functions are combined in a main function, possible linkages of these functions are established via variation points, executable program code is generated for all functions, and functions or their linkages are activated via programmable variation points. The method is particularly suitable for testing function variants in a motor vehicle.