Abstract: A feeder device for feeding powder, having a barrel feeding channel with a downstream end. The feeding channel including at least one conveying element for conveying the powder material to the downstream end. A rotatable exit element provided at the downstream end of the feeding channel. The rotatable exit element includes an annular portion defining exit openings defined by powder engaging edges. The rotatable exit element is positioned transversally outside the barrel in a proximity of the downstream end of the feeding channel. The feeding channel has a first, inner diameter and the rotatable exit element has a second, outer diameter, where the second, outer diameter is equal to or larger than the first inner diameter.

Abstract: A method for processing pharmaceutical powders, which comprises providing a feeder module including a plurality of feeder units each with a storage hopper, a weighing cell, a conveyer, and a discharge end, connecting the storage hopper to a refilling system with a refilling valve, connecting the refilling valve to a level or weight indicator disposed above the refilling valve, connecting the discharge end to a common receiving container, refilling the storage hopper with a powder intermittently 40 to 80 times per hour, storing data during refilling, transporting powder from the storage hopper with the respective conveyer, and discharging powder from each feeder unit into the common receiving container. During each refilling of the storage hopper, the refilling valve dispenses powder into the storage hopper and, during the step of transporting the powder from the storage hopper, the conveyer is operated according to the data collected during previous refills.

Abstract: A feeder device for feeding powder, having a barrel feeding channel with a downstream end. The feeding channel including at least one conveying element for conveying the powder material to the downstream end. A rotatable exit element provided at the downstream end of the feeding channel. The rotatable exit element includes an annular portion defining exit openings defined by powder engaging edges. The rotatable exit element is positioned transversally outside the barrel in a proximity of the downstream end of the feeding channel. The feeding channel has a first, inner diameter and the rotatable exit element has a second, outer diameter, where the second, outer diameter is equal to or larger than the first inner diameter.

Abstract: A method for processing pharmaceutical powders, which comprises providing a feeder module including a plurality of feeder units each with a storage hopper, a weighing cell, a conveyer, and a discharge end, connecting the storage hopper to a refilling system with a refilling valve, connecting the refilling valve to a level or weight indicator disposed above the refilling valve, connecting the discharge end to a common receiving container, refilling the storage hopper with a powder intermittently 40 to 80 times per hour, storing data during refilling, transporting powder from the storage hopper with the respective conveyer, and discharging powder from each feeder unit into the common receiving container. During each refilling of the storage hopper, the refilling valve dispenses powder into the storage hopper and, during the step of transporting the powder from the storage hopper, the conveyer is operated according to the data collected during previous refills.

Abstract: A method for processing pharmaceutical powders, which comprises providing a feeder module including a plurality of feeder units each with a storage hopper, a weighing cell, a conveyer, and a discharge end, connecting the storage hopper to a refilling system with a refilling valve, connecting the refilling valve to a level or weight indicator disposed above the refilling valve, connecting the discharge end to a common receiving container, refilling the storage hopper with a powder intermittently 40 to 80 times per hour, storing data during refilling, transporting powder from the storage hopper with the respective conveyer, and discharging powder from each feeder unit into the common receiving container. During each refilling of the storage hopper, the refilling valve dispenses powder into the storage hopper and, during the step of transporting the powder from the storage hopper, the conveyer is operated according to the data collected during previous refills.

Abstract: A method for processing pharmaceutical powders, which comprises providing a feeder module including a plurality of feeder units each with a storage hopper, a weighing cell, a conveyer, and a discharge end, connecting the storage hopper to a refilling system with a refilling valve, connecting the refilling valve to a level or weight indicator disposed above the refilling valve, connecting the discharge end to a common receiving container, refilling the storage hopper with a powder intermittently 40 to 80 times per hour, storing data during refilling, transporting powder from the storage hopper with the respective conveyer, and discharging powder from each feeder unit into the common receiving container. During each refilling of the storage hopper, the refilling valve dispenses powder into the storage hopper and, during the step of transporting the powder from the storage hopper, the conveyer is operated according to the data collected during previous refills.

Abstract: Method for transfer of containers, such as vials (101), between a freeze dryer (1) that is located at a first location and a separate transport vehicle (30) that is mobile with respect to the freeze dryer, wherein the freeze dryer (1) comprises a freeze dryer housing (2) with an access opening (11) towards an inner freeze drying chamber (10) inside the freeze dryer housing (2), multiple shelves (21-24) that are arranged spaced apart above each other inside the freeze dryer chamber (10) and each provided with a horizontally extending first flat supporting surface (25) for supporting the containers, wherein the mobile transport vehicle (30) comprises a mobile undercarriage (31) supporting a storage housing (33) with an access opening (40) towards an inner storage chamber (39), a carrier provided with a second flat supporting surface (58) for supporting the containers inside the storage housing (33), and a container shifter (60) for pushing out containers away from the second flat supporting surface (58) in a pu

Abstract: A feeder unit comprises a storage hopper, a weighing cell, a conveyer, and a discharge end. The storage hopper is to be connected to a refilling system and the discharge end to a receiving container. A working space is defined by the arithmetic product of the dead weight of the feeder unit and the refilling interval, such that the working space is below 0.2 kgh. Furthermore a method for discharging a constant mass flow of one or more powders into a receiving container is defined.

Abstract: Method for transfer of containers, such as vials (101), between a freeze dryer (1) that is located at a first location and a separate transport vehicle (30) that is mobile with respect to the freeze dryer, wherein the freeze dryer (1) comprises a freeze dryer housing (2) with an access opening (11) towards an inner freeze drying chamber (10) inside the freeze dryer housing (2), multiple shelves (21-24) that are arranged spaced apart above each other inside the freeze dryer chamber (10) and each provided with a horizontally extending first flat supporting surface (25) for supporting the containers, wherein the mobile transport vehicle (30) comprises a mobile undercarriage (31) supporting a storage housing (33) with an access opening (40) towards an inner storage chamber (39), a carrier provided with a second flat supporting surface (58) for supporting the containers inside the storage housing (33), and a container shifter (60) for pushing out containers away from the second flat supporting surface (58) in a pu

Abstract: A method of determining the mass of a moving sample is described, in which the sample is moved at a controlled velocity through a mass interrogation zone and a temperature interrogation zone, which may be upstream or downstream from the mass interrogation zone.