Abstract: This disclosure relates to a rapid molecular imaging strategy that utilizes Raman spectroscopy to interrogate the molecular expression of samples, for example, histology samples. This disclosure also relates to surface-enhanced Raman spectroscopy nanoparticles (SERS-NP) as contrast agents that exhibit unsurpassed multiplexing capabilities to offer exceptional specificity. This disclosure also relates to a SERS-NP comprising a Raman active metallic core, a Raman active layer, and a shell that may offer ultra-high diagnostic sensitivity (e.g., femtomolar level). This disclosure also relates to chemically modifying these new contrast agents to target a plurality of biomarkers within the sample. This disclosure also relates to rapid assessment of the molecular expression profile of the entire sample, for example, a whole tissue section, in a single image.

Abstract: Coated catalysts comprising a catalytically active multimetal oxide comprising molybdenum. The coated catalyst comprises a support body, a first layer and a second layer. The first layer comprises a molybdenum oxide or a precursor compound which forms molybdenum oxide. The second layer comprises a multimetal oxide comprising molybdenum and at least one further metal.

Abstract: The invention relates to a coated catalyst, which is obtainable from a catalyst precursor comprising (a) a support body, (b) a coating comprising (i) a catalytically active, multimetal oxide which comprises molybdenum and at least one further metal and is of the general formula (I) Mo12BiaCrbX1cFedX2eX3fOy??(I) where X1=Co and/or Ni, X2=Si and/or Al, X3=Li, Na, K, Cs and/or Rb, 0.2?a?1, 0?b?2, 2?c?10, 0.5?d?10, 0?e?10, 0?f?0.5 and y=a number which, with the prerequisite of charge neutrality, is determined by the valency and frequency of the elements in (I) other than oxygen, and (ii) at least one pore former.

Abstract: The invention relates to a coated catalyst comprising (a) a support body, (b) a first layer comprising a molybdenum oxide or a precursor compound which forms molybdenum oxide, (c) a second layer comprising a multimetal oxide comprising molybdenum and at least one further metal. The molybdenum oxide of the first layer is preferably MoO3. The multimetal oxide of the second layer is preferably a multimetal oxide of the general formula II Mo12BiaCrbX1cFedX2eX3fOy ??(II).