Patents by Inventor Alexander DePaoli

Alexander DePaoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of Myostatin Antagonists
    Publication number: 20140294866
    Abstract: The present invention provides methods for treating disorders arising from hypogonadism by administering myostatin antagonists to subjects suffering from such disorders.
    Type: Application
    Filed: June 19, 2014
    Publication date: October 2, 2014
    Inventors: Huiquan Han, Alexander DePaoli, John Zhao-Nian Lu, Jin Lin Wang
  • Uses of Myostatin Antagonists
    Publication number: 20110008375
    Abstract: The present invention provides methods for treating disorders arising from hypogonadism, rheumatoid cachexia, cachexia due to burns, cachexia due to administration of chemical agents, cachexia due to diabetes, diabetic nephropathy, Prader Willi syndrome, excessive TNF-?, and other muscle-related, metabolic and inflammatory disorders by administering myostatin antagonists to subjects suffering from such disorders.
    Type: Application
    Filed: September 27, 2010
    Publication date: January 13, 2011
    Inventors: HAN HQ, ALEXANDER DEPAOLI, JOHN ZHAO-NIAN LU, JIN LIN WANG
  • Uses of myostatin antagonists
    Publication number: 20070149458
    Abstract: The present invention provides methods for treating disorders arising from hypogonadism, rheumatoid cachexia, cachexia due to burns, cachexia due to administration of chemical agents, cachexia due to diabetes, diabetic nephropathy, Prader Willi syndrome, excessive TNF-?, and other muscle-related, metabolic and inflammatory disorders by administering myostatin antagonists to subjects suffering from such disorders.
    Type: Application
    Filed: December 6, 2006
    Publication date: June 28, 2007
    Applicant: Amgen Inc.
    Inventors: Hq Han, Alexander DePaoli, John Lu, Jin Wang
  • Use of leptin for treating human lipoatrophy and method of determining predisposition to said treatment
    Publication number: 20070099836
    Abstract: Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipoatrophy. Leptin is effective against conditions of lipoatrophy for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including subcutaneously and using gene therapy methods. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having a leptin level of approximately 4 ng/ml or less before treatment.
    Type: Application
    Filed: November 29, 2006
    Publication date: May 3, 2007
    Applicants: Amgen, Inc., The Govt. of the U.S.A. as represented by the Secretary, Dept. of Health & Human Services, Board of Regents, The University of Texas System
    Inventors: Alexander DePaoli, Simeon Taylor, Elif Oral, Abhimanyu Garg
  • Use of leptin for treating human lipoatrophy and method of determining predisposition to said treatment
    Publication number: 20050020496
    Abstract: Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipoatrophy. Leptin is effective against conditions of lipoatrophy for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including subcutaneously and using gene therapy methods. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having a leptin level of approximately 4 ng/ml or less before treatment.
    Type: Application
    Filed: July 18, 2003
    Publication date: January 27, 2005
    Inventors: Alexander DePaoli, Simeon Taylor, Elif Oral, Abhimanyu Garg